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Crystal Structure of the A2A-StaR2-bRIL562 in complex with AZD4635 at 2.0A resolution
分子名称:	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 6-(2-chloranyl-6-methyl-pyridin-4-yl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine, Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, ...
著者	Borodovsky, A, Wang, Y, Deng, N, Ye, M, Stephen, T.L, Goodwin, K, Goodwin, R, Strittmatter, N, Shaw, J, Sachsenmeier, K, Clarke, J.D, Hay, C, Reimer, C, Andrews, S.P, Brown, G.A, Congreve, M, Cheng, R.K.Y, Dore, A.S, Mason, J.S, Marshall, F.H, Weir, M.P, Lyne, P, Woessner, R.
登録日	2018-06-15
公開日	2019-06-26
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Small molecule AZD4635 inhibitor of A2AR signaling rescues immune cell function including CD103+ dendritic cells enhancing anti-tumor immunity J Immunother Cancer, 2020

Human JAK1 kinase in complex with compound 30 at 2.30 Angstroms resolution
分子名称:	6-chloro-2-(2-fluoro-4,5-dimethoxyphenyl)-N-(piperidin-4-ylmethyl)-3H-imidazo[4,5-b]pyridin-7-amine, DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase JAK1
著者	Ferguson, A.D.
登録日	2015-09-29
公開日	2015-11-25
最終更新日	2015-12-30
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Identification of azabenzimidazoles as potent JAK1 selective inhibitors. Bioorg.Med.Chem.Lett., 26, 2016