1C2U
 
 | | SOLUTION STRUCTURE OF [ABU3,35]SHK12-28,17-32 | | 分子名称: | SYNTHETIC PEPTIDE ANALOGUE OF SHK TOXIN | | 著者 | Pennington, M.W, Lanigan, M.D, Kalman, K, Manhir, V.M, Rauer, H, McVaugh, C.T, Behm, D, Donaldson, D, Chandy, K.G, Kem, W.R, Norton, R.S. | | 登録日 | 1999-07-27 | | 公開日 | 1999-11-10 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Role of disulfide bonds in the structure and potassium channel blocking activity of ShK toxin.
Biochemistry, 38, 1999
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7LTZ
 | | Bruton's tyrosine kinase in complex with compound 51 | | 分子名称: | 1-~{tert}-butyl-~{N}-[(5~{R})-8-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-2-(oxetan-3-yl)-1,3,4,5-tetrahydro-2-benzazepin-5-yl]-1,2,3-triazole-4-carboxamide, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, ... | | 著者 | Metrick, C.M, Marcotte, D.J. | | 登録日 | 2021-02-20 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis.
J.Med.Chem., 65, 2022
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7LTY
 | | Bruton's tyrosine kinase in complex with compound 23 | | 分子名称: | DIMETHYL SULFOXIDE, Isoform BTK-C of Tyrosine-protein kinase BTK, ~{N}-[(5~{R})-2-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{H}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide | | 著者 | Metrick, C.M, Marcotte, D.J. | | 登録日 | 2021-02-20 | | 公開日 | 2022-01-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis.
J.Med.Chem., 65, 2022
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