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1S5V
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Crystal Structure Analysis of a mutant of DIHYDRODIPICOLINATE SYNTHASE--residue Tyr107 to Phe107
分子名称: Dihydrodipicolinate synthase
著者Dobson, R.C.J, Valegard, K, Gerrard, J.A.
登録日2004-01-21
公開日2004-04-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The Crystal Structure of Three Site-directed Mutants of Escherichia coli Dihydrodipicolinate Synthase: Further Evidence for a Catalytic Triad
J.MOL.BIOL., 338, 2004
1S5W
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BU of 1s5w by Molmil
Crystal Structure Analysis of a mutant of DIHYDRODIPICOLINATE SYNTHASE--residue Tyr133 to Phe133
分子名称: Dihydrodipicolinate synthase
著者Dobson, R.C.J, Valegard, K, Gerrard, J.A.
登録日2004-01-21
公開日2004-04-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献The Crystal Structure of Three Site-directed Mutants of Escherichia coli Dihydrodipicolinate Synthase: Further Evidence for a Catalytic Triad
J.MOL.BIOL., 338, 2004
1S5T
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BU of 1s5t by Molmil
Crystal Structure Analysis of a mutant of DIHYDRODIPICOLINATE SYNTHASE--residue thr44 to val44
分子名称: Dihydrodipicolinate synthase
著者Dobson, R.C.J, Valegard, K, Gerrard, J.A.
登録日2004-01-21
公開日2004-04-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of Three Site-directed Mutants of Escherichia coli Dihydrodipicolinate Synthase: Further Evidence for a Catalytic Triad
J.MOL.BIOL., 338, 2004
3C0J
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BU of 3c0j by Molmil
Structure of E. coli dihydrodipicolinate synthase complexed with hydroxypyruvate
分子名称: Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ...
著者Dobson, R.C.J.
登録日2008-01-21
公開日2008-09-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conserved main-chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase
Protein Sci., 17, 2008
3QGU
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L,L-Diaminopimelate aminotransferase from Chlamydomonas reinhardtii
分子名称: AZIDE ION, GLYCEROL, LL-diaminopimelate aminotransferase, ...
著者Dobson, R.C.J, Giron, I, Hudson, A.O.
登録日2011-01-25
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献L,L-Diaminopimelate Aminotransferase from Chlamydomonas reinhardtii: A Target for Algaecide Development
Plos One, 6, 2011
3A5F
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High-resolution structure of DHDPS from Clostridium botulinum in complex with pyruvate
分子名称: Dihydrodipicolinate synthase, GLYCEROL
著者Atkinson, S.C, Dobson, R.C.J, Perugini, M.A.
登録日2009-08-06
公開日2010-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献The high resolution structure of DHDPS from Clostridium botulinum
To be Published
3DAQ
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BU of 3daq by Molmil
Crystal structure of dihydrodipicolinate synthase from methicillin-resistant Staphylococcus aureus
分子名称: CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL
著者Dobson, R.C.J, Burgess, B.R, Jameson, G.B, Gerrard, J.A, Parker, M.W, Perugini, M.A.
登録日2008-05-29
公開日2008-08-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure and evolution of a novel dimeric enzyme from a clinically-important bacterial pathogen.
J.Biol.Chem., 2008
3IRD
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BU of 3ird by Molmil
Structure of dihydrodipicolinate synthase from Clostridium botulinum
分子名称: CHLORIDE ION, D-MALATE, Dihydrodipicolinate synthase, ...
著者Dobson, R.C.J, Atkinson, S, Perugini, M.A.
登録日2009-08-22
公開日2009-09-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structure of Cbot-DHDPS
To be Published
8THJ
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Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (antiparallel dimer)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ...
著者Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A.
登録日2023-07-16
公開日2023-11-22
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
Elife, 12, 2024
8THI
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Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (parallel dimer)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, SODIUM ION, Sialic acid TRAP transporter permease protein SiaT
著者Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A.
登録日2023-07-16
公開日2023-11-22
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
Elife, 12, 2024
7QHA
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Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Photobacterium profundum in amphipol
分子名称: Megabody c7HopQ, Putative TRAP-type C4-dicarboxylate transport system, large permease component, ...
著者North, R.A, Davies, J.S, Morado, D, Dobson, R.C.J.
登録日2021-12-11
公開日2022-12-21
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 14, 2023
8B01
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Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Photobacterium profundum in a nanodisc
分子名称: DECANE, DOCOSANE, HEXANE, ...
著者Davies, J.S, North, R.A, Dobson, R.C.J.
登録日2022-09-06
公開日2023-03-15
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 14, 2023
8GEK
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Dihydrodipicolinate synthase with pyruvate from Candidatus Liberibacter solanacearum
分子名称: 4-hydroxy-tetrahydrodipicolinate synthase
著者Gilkes, J.M, Frampton, R.A, Board, A, Sheen, C.R, Smith, G.R, Dobson, R.C.J.
登録日2023-03-06
公開日2024-03-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Dihydrodipicolinate synthase with pyruvate from the plant pathogen, Candidatus Liberibacter solanacearum
To Be Published
6H4E
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BU of 6h4e by Molmil
Proteus mirabilis N-acetylneuraminate lyase
分子名称: Putative N-acetylneuraminate lyase, SULFATE ION
著者North, R.A, Garcia-Bonete, M.J, Goyal, P, Katona, G, Dobson, R.C.J, Friemann, R.
登録日2018-07-21
公開日2019-06-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.561 Å)
主引用文献The structure of Proteus mirabilis N-acetylneuraminate lyase reveals an intermolecular disulphide bond
To Be Published
7T3E
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BU of 7t3e by Molmil
Structure of the sialic acid bound Tripartite ATP-independent Periplasmic (TRAP) periplasmic component SiaP from Photobacterium profundum
分子名称: N-acetyl-beta-neuraminic acid, SULFATE ION, TRAP-type C4-dicarboxylate transport system, ...
著者Davies, J.S, Currie, M.J, North, R.A, Dobson, R.C.J.
登録日2021-12-07
公開日2022-12-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter.
Nat Commun, 14, 2023
4OY5
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0.89 Angstrom resolution crystal structure of (Gly-Pro-Hyp)10
分子名称: Collagen
著者Suzuki, H, Mahapatra, D, Steel, P.J, Dyer, J, Dobson, R.C.J, Gerrard, J.A, Valery, C.
登録日2014-02-10
公開日2015-03-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (0.89 Å)
主引用文献Sub-angstrom structure of the collagen model peptide (GPO)10 shows a hydrated triple helix with pitch variation and two proline ring conformations
To Be Published
2ATS
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BU of 2ats by Molmil
Dihydrodipicolinate synthase co-crystallised with (S)-lysine
分子名称: CHLORIDE ION, D-LYSINE, POTASSIUM ION, ...
著者Devenish, S.R.A, Dobson, R.C.J, Jameson, G.B, Gerrard, J.A.
登録日2005-08-26
公開日2006-09-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The co-crystallisation of (S)-lysine-bound dihydrodipicolinate synthase from E. coli indicates that domain movements are not responsible for (S)-lysine inhibition
To be published
7MJF
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BU of 7mjf by Molmil
Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
分子名称: (4R)-4-oxidanyl-2-oxidanylidene-heptanedioic acid, (4S)-4-hydroxy-2-oxoheptanedioic acid, 4-hydroxy-tetrahydrodipicolinate synthase
著者Gilkes, J, Frampton, R.A, Board, A.J, Sheen, C.R, Smith, G.R, Dobson, R.C.J.
登録日2021-04-20
公開日2021-07-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Candidatus Liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
To Be Published
7RUM
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BU of 7rum by Molmil
Endolysin from Escherichia coli O157:H7 phage FTEbC1, LysT84
分子名称: Endolysin, GLYCEROL
著者Love, M.J, Billington, C, Dobson, R.C.J.
登録日2021-08-17
公開日2022-02-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献The structure and function of modular Escherichia coli O157:H7 bacteriophage FTBEc1 endolysin, LysT84: defining a new endolysin catalytic subfamily.
Biochem.J., 479, 2022
4C1K
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Crystal structure of pyrococcus furiosus 3-deoxy-D-arabino- heptulosonate 7-phosphate synthase
分子名称: 2-DEHYDRO-3-DEOXYPHOSPHOHEPTONATE ALDOLASE, CADMIUM ION, CARBONATE ION, ...
著者Nazmi, A.R, Schofield, L.R, Dobson, R.C.J, Jameson, G.B, Parker, E.J.
登録日2013-08-13
公開日2013-11-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Destabilization of the Homotetrameric Assembly of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase from the Hyperthermophile Pyrococcus Furiosus Enhances Enzymatic Activity
J.Mol.Biol., 426, 2014
4IJZ
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Crystal structure of diaminopimelate epimerase from Escherichia coli
分子名称: Diaminopimelate epimerase, NITRATE ION
著者Hor, L, Dobson, R.C.J, Hutton, C.A, Perugini, M.A.
登録日2012-12-24
公開日2013-02-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dimerization of bacterial diaminopimelate epimerase is essential for catalysis
J.Biol.Chem., 288, 2013
4I7U
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Dihydrodipicolinate Synthase of Agrobacterium tumefaciens
分子名称: Dihydrodipicolinate synthase, GLYCEROL
著者Atkinson, S.C, Dogovski, C, Dobson, R.C.J, Perugini, M.A.
登録日2012-11-30
公開日2013-12-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure, function and allostery of the bona fide DHDPS from the plant pathogen Agrobacterium tumefaciens
To be Published
4IK0
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Crystal structure of diaminopimelate epimerase Y268A mutant from Escherichia coli
分子名称: Diaminopimelate epimerase, IODIDE ION
著者Hor, L, Dobson, R.C.J, Hutton, C.A, Perugini, M.A.
登録日2012-12-24
公開日2013-02-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Dimerization of bacterial diaminopimelate epimerase is essential for catalysis
J.Biol.Chem., 288, 2013
7M5I
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Endolysin from Escherichia coli O157:H7 phage FAHEc1
分子名称: Endolysin, PHOSPHATE ION
著者Love, M.J, Coombes, D, Billington, C, Dobson, R.C.J.
登録日2021-03-24
公開日2021-08-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献The Molecular Basis for Escherichia coli O157:H7 Phage FAHEc1 Endolysin Function and Protein Engineering to Increase Thermal Stability.
Viruses, 13, 2021
7MFS
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N-Acetylmannosamine-6-phosphate 2-epimerase from Staphylococcus aureus (strain MRSA USA300) with substrate and product bound
分子名称: CHLORIDE ION, N-acetyl-D-glucosamine-6-phosphate, N-acetylmannosamine-6-phosphate, ...
著者Currie, M.J, Dobson, R.C.J.
登録日2021-04-11
公開日2022-04-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization.
J.Biol.Chem., 297, 2021

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