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CRYSTAL STRUCTURE OF CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH A COVALENT PEPTIDOMIMETIC INHIBITOR
分子名称:	1-[2-(3-BIPHENYL)-4-METHYLVALERYL)]AMINO-3-(2-PYRIDYLSULFONYL)AMINO-2-PROPANONE, CATHEPSIN K
著者	Desjarlais, R.L, Yamashita, D.S, Oh, H.-J, Bondinell, W.E, Uzinskas, I.N, Erhard, K.F, Allen, A.C, Haltiwanger, R.C, Zhao, B, Smith, W.W, Abdel-Meguid, S.S, D'Alessio, K, Janson, C.A, Mcqueney, M.S, Tomaszek, T.A, Levy, M.A, Veber, D.F.
登録日	1998-05-29
公開日	1999-06-08
最終更新日	2023-08-02
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Use of X-Ray Co-Crystal Structures and Molecular Modeling to Design Potent and Selective Non-Peptide Inhibitors of Cathepsin K J.Am.Chem.Soc., 120, 1998

CRYSTAL STRUCTURE OF THE CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH A COVALENT AZEPANONE INHIBITOR
分子名称:	BENZOFURAN-2-CARBOXYLIC ACID {(S)-3-METHYL-1-[3-OXO-1-(PYRIDIN-2-YLSULFONYL)AZEPAN-4-YLCARBAMOYL]BUTYL}AMIDE, CATHEPSIN K
著者	Smith, W.W, Janson, C.A, Zhao, B.
登録日	2003-01-07
公開日	2003-01-14
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Azepanone-Based Inhibitors of Human and Rat Cathepsin K J.Med.Chem., 44, 2001

Crystal Structure Of The Cysteine Protease Human Cathepsin K In Complex With A Covalent Azepanone Inhibitor
分子名称:	5-(2-MORPHOLIN-4-YLETHOXY)BENZOFURAN-2-CARBOXYLIC ACID ((S)-3-METHYL-1-{(S)-3-OXO-1-[2-(3-PYRIDIN-2-YLPHENYL)ACETYL]AZEPAN-4-YLCARBAMOYL}BUTYL)AMIDE, Cathepsin K
著者	Smith, W.W, Janson, C.A, Zhao, B.
登録日	2003-01-06
公開日	2003-01-14
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Azepanone-based inhibitors of human and rat cathepsin K J.Med.Chem., 44, 2001

CRYSTAL STRUCTURE OF THE CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH THE COVALENT INHIBITOR E-64
分子名称:	CATHEPSIN K, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE
著者	Zhao, B, Smith, W.W, Janson, C.A, Abdel-Meguid, S.S.
登録日	1996-12-19
公開日	1998-02-04
最終更新日	2023-08-02
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Crystal structure of human osteoclast cathepsin K complex with E-64. Nat.Struct.Biol., 4, 1997