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A45G p-hydroxybenzoate hydroxylase with p-hydroxybenzoate bound
分子名称:	FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID, P-hydroxybenzoate hydroxylase, ...
著者	Cole, L.J, Gatti, D.L, Entsch, B, Ballou, D.P.
登録日	2005-01-18
公開日	2005-07-26
最終更新日	2023-08-23
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Removal of a methyl group causes global changes in p-hydroxybenzoate hydroxylase. Biochemistry, 44, 2005

Hepatitis C Protease NS3-4A serine protease with Ketoamide Inhibitor SCH225724 Bound
分子名称:	({1-[1-CARBAMOYL-PHENYL-METHYL)-CARBAMOYL]-METHYL}-AMINOOXALYL)-BUTYLCARBAMOYL)-3-METHYL-BUTYLCARBAMOYL)-CYCLOHEXYL-METHYL)-CARBAMIC ACID ISOBUTYL ESTER, NS3 protease/helicase, NS4a peptide, ...
著者	Arasappan, A, Njoroge, F.G, Chan, T.Y, Bennett, F, Bogen, S.L, Chen, K, Gu, H, Hong, L, Jao, E, Liu, Y.T, Lovey, R.G, Parekh, T, Pike, R.E, Pinto, P, Santhanam, B, Venkatraman, S, Vaccaro, H, Wang, H, Yang, X, Zhu, Z, Mckittrick, B, Saksena, A.K, Girijavallabhan, V, Pichardo, J, Butkiewicz, N, Ingram, R, Malcolm, B, Prongay, A.J, Yao, N, Marten, B, Madison, V, Kemp, S, Levy, O, Lim-Wilby, M, Tamura, S, Ganguly, A.K.
登録日	2005-06-28
公開日	2006-07-04
最終更新日	2024-10-09
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Hepatitis C virus NS3-4a serine protease inhibitors. SAR of P2' moiety with improved potency. Bioorg.Med.Chem.Lett., 15, 2005

HCV NS3 protease with NS4a peptide and a covalently bound macrocyclic ketoamide compound.
分子名称:	(2R)-({N-[(3S)-3-({[(3S,6S)-6-CYCLOHEXYL-5,8-DIOXO-4,7-DIAZABICYCLO[14.3.1]ICOSA-1(20),16,18-TRIEN-3-YL]CARBONYL}AMINO)-2-OXOHEXANOYL]GLYCYL}AMINO)(PHENYL)ACETIC ACID, BETA-MERCAPTOETHANOL, NS3 protease/helicase', ...
著者	Chen, K.X, Njoroge, F.G, Prongay, A, Pichardo, J, Madison, V, Girijavallabhan, V.
登録日	2005-06-29
公開日	2006-07-04
最終更新日	2021-10-20
実験手法	X-RAY DIFFRACTION (2.45 Å)
主引用文献	Synthesis and Biological Activity of Macrocyclic Inhibitors of Hepatitis C Virus (HCV) NS3 Protease Bioorg.Med.Chem.Lett., 15, 2005