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Triazolopyridine compounds as selective JAK1 inhibitors: from hit identification to GLPG0634
分子名称:	N-(5-{4-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide, Tyrosine-protein kinase JAK2
著者	Menet, C.C.J, Fletcher, S, Van Lommen, G, Geney, R, Blanc, J, Smits, K, Jouannigot, N, van der Aar, E.M, Clement-Lacroix, P, Lepescheux, L, Galien, R, Vayssiere, B, Nelles, L, Christophe, T, Brys, R, Uhring, M, Ciesielski, F, Van Rompaey, L.
登録日	2014-03-27
公開日	2014-11-19
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Triazolopyridines as Selective JAK1 Inhibitors: From Hit Identification to GLPG0634. J.Med.Chem., 57, 2014

Structure of ar lbd with activator peptide and sarm inhibitor 1
分子名称:	4-[(4R)-4-(4-hydroxyphenyl)-3,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile, Androgen receptor, activator peptide, ...
著者	Nique, F, Hebbe, S, Peixoto, C, Annoot, D, Lefrancois, J.-M, Duval, E, Michoux, L, Triballeau, N, Lemoullec, J.-M, Mollat, P, Thauvin, M, Prange, T, Minet, D, Clement-Lacroix, P, Robin-Jagerschmidt, C, Fleury, D, Guedin, D, Deprez, P.
登録日	2011-12-14
公開日	2012-09-05
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Discovery of diarylhydantoins as new selective androgen receptor modulators. J.Med.Chem., 55, 2012

Structure of ar lbd with activator peptide and sarm inhibitor 2
分子名称:	(5R)-3-(3,4-dichlorophenyl)-5-(4-hydroxyphenyl)-1,5-dimethyl-2-thioxoimidazolidin-4-one, Androgen receptor, SULFATE ION
著者	Nique, F, Hebbe, S, Peixoto, C, Annoot, D, Lefrancois, J.-M, Duval, E, Michoux, L, Triballeau, N, Lemoullec, J.M, Mollat, P, Thauvin, M, Prange, T, Minet, D, Clement-Lacroix, P, Robin-Jagerschmidt, C, Fleury, D, Guedin, D, Deprez, P.
登録日	2011-12-14
公開日	2012-09-05
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	Discovery of diarylhydantoins as new selective androgen receptor modulators. J.Med.Chem., 55, 2012