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Crystal Structure of Werner helicase fragment 517-945 in complex with ADP
分子名称:	1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, ...
著者	Classen, M, Benz, J, Brugger, D, Rudolph, M.G.
登録日	2023-10-19
公開日	2024-05-01
最終更新日	2024-05-29
実験手法	X-RAY DIFFRACTION (1.57 Å)
主引用文献	Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase. Nature, 629, 2024

Crystal Structure of Werner helicase fragment 517-945 in covalent complex with N-[(E,1S)-1-cyclopropyl-3-methylsulfonylprop-2-enyl]-2-(1,1-difluoroethyl)-4-phenoxypyrimidine-5-carboxamide
分子名称:	ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, GLYCEROL, ...
著者	Classen, M, Benz, J, Brugger, D, Tagliente, O, Rudolph, M.G.
登録日	2023-10-19
公開日	2024-05-01
最終更新日	2024-05-29
実験手法	X-RAY DIFFRACTION (1.54 Å)
主引用文献	Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase. Nature, 629, 2024

Crystal Structure of Werner helicase fragment 517-945 in complex with ATP
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, MAGNESIUM ION, ...
著者	Classen, M, Benz, J, Brugger, D, Rudolph, M.G.
登録日	2023-10-19
公開日	2024-05-01
最終更新日	2024-05-29
実験手法	X-RAY DIFFRACTION (2.21 Å)
主引用文献	Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase. Nature, 629, 2024

Structure of the streptomyces subtilisin and TAMP inhibitor (SSTI)
分子名称:	Transglutaminase-activating metalloprotease inhibitor
著者	Schmelz, S, Juettner, N.E, Fuchsbauer, H.L, Scrima, A.
登録日	2018-10-26
公開日	2019-09-04
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (1.448 Å)
主引用文献	The N-terminal peptide of the transglutaminase-activating metalloprotease inhibitor from Streptomyces mobaraensis accommodates both inhibition and glutamine cross-linking sites. Febs J., 287, 2020