6OF0
| Structural basis for multidrug recognition and antimicrobial resistance by MTRR, an efflux pump regulator from Neisseria Gonorrhoeae | 分子名称: | HTH-type transcriptional regulator MtrR, PHOSPHATE ION | 著者 | Beggs, G.A, Kumaraswami, M, Shafer, W, Brennan, R.G. | 登録日 | 2019-03-28 | 公開日 | 2019-07-31 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural, Biochemical, and In Vivo Characterization of MtrR-Mediated Resistance to Innate Antimicrobials by the Human Pathogen Neisseria gonorrhoeae . J.Bacteriol., 201, 2019
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7JU3
| MtrR bound to the mtrCDE operator from Neisseria gonorrhoeae | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*CP*AP*TP*AP*CP*AP*CP*GP*AP*TP*TP*GP*CP*AP*CP*GP*GP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*CP*CP*GP*TP*GP*CP*AP*AP*TP*CP*GP*TP*GP*TP*AP*TP*GP*T)-3'), ... | 著者 | Beggs, G.A, Shafer, W.M, Brennan, R.G. | 登録日 | 2020-08-19 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations. Nucleic Acids Res., 49, 2021
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7JNP
| MtrR bound to the rpoH operator from Neisseria gonorrhoeae | 分子名称: | CALCIUM ION, DNA (5'-D(*TP*AP*CP*AP*TP*AP*CP*GP*TP*GP*GP*TP*TP*GP*TP*AP*TP*GP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*AP*CP*AP*TP*AP*CP*AP*AP*CP*CP*AP*CP*GP*TP*AP*TP*GP*TP*A)-3'), ... | 著者 | Beggs, G.A, Shafer, W.M, Brennan, R.G. | 登録日 | 2020-08-05 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations. Nucleic Acids Res., 49, 2021
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8SSH
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8FW0
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8FW3
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8FW8
| MtrR from Neisseria gonorrhoeae bound to Progesterone | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, HTH-type transcriptional regulator MtrR, PHOSPHATE ION, ... | 著者 | Hooks, G.H, Brennan, R.G. | 登録日 | 2023-01-20 | 公開日 | 2024-01-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Hormonal steroids induce multidrug resistance and stress response genes in Neisseria gonorrhoeae by binding to MtrR. Nat Commun, 15, 2024
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