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2RVH
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BU of 2rvh by Molmil
NMR structure of eIF1
分子名称: Eukaryotic translation initiation factor eIF-1
著者Nagata, T, Obayashi, E, Asano, K.
登録日2015-10-16
公開日2016-10-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5
Cell Rep, 18, 2017
2OGH
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BU of 2ogh by Molmil
Solution structure of yeast eIF1
分子名称: Eukaryotic translation initiation factor eIF-1
著者Reibarkh, M, del Rio, F, Yamamoto, Y, Asano, K, Wagner, G.
登録日2007-01-05
公開日2007-11-20
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Eukaryotic Initiation Factor (eIF) 1 Carries Two Distinct eIF5-binding Faces Important for Multifactor Assembly and AUG Selection.
J.Biol.Chem., 283, 2008
8IFC
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BU of 8ifc by Molmil
Arbekacin-bound E.coli 70S ribosome in the PURE system
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T.
登録日2023-02-17
公開日2024-02-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside.
J.Biochem., 175, 2024
8IFE
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BU of 8ife by Molmil
Arbekacin-added human 80S ribosome
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T.
登録日2023-02-17
公開日2024-02-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside.
J.Biochem., 175, 2024
8IFD
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BU of 8ifd by Molmil
Dibekacin-added human 80S ribosome
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T.
登録日2023-02-17
公開日2024-02-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside.
J.Biochem., 175, 2024
8IFB
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BU of 8ifb by Molmil
Dibekacin-bound E.coli 70S ribosome in the PURE system
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T.
登録日2023-02-17
公開日2024-02-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.43 Å)
主引用文献Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside.
J.Biochem., 175, 2024
5YT0
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BU of 5yt0 by Molmil
Crystal structure of the complex of archaeal ribosomal stalk protein aP1 and archaeal translation initiation factor aIF5B
分子名称: Archaeal ribosomal stalk protein aP1, GUANOSINE-5'-DIPHOSPHATE, Probable translation initiation factor IF-2
著者Murakami, R, Singh, C.R, Morris, J, Tang, L, Harmon, I, Miyoshi, T, Ito, K, Asano, K, Uchiumi, T.
登録日2017-11-16
公開日2018-06-27
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献The Interaction between the Ribosomal Stalk Proteins and Translation Initiation Factor 5B Promotes Translation Initiation
Mol. Cell. Biol., 38, 2018
3WY8
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BU of 3wy8 by Molmil
Crystal Structure of Protease Anisep from Arthrobacter Nicotinovorans
分子名称: Serine protease
著者Sone, T, Haraguchi, Y, Kuwahara, A, Ose, T, Takano, M, Abe, A, Tanaka, M, Tanaka, I, Asano, K.
登録日2014-08-20
公開日2015-08-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural characterization reveals the keratinolytic activity of an arthrobacter nicotinovorans protease.
Protein Pept.Lett., 22, 2015
4PF3
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BU of 4pf3 by Molmil
Mineralocorticoid receptor ligand-binding domain with compuond 37a
分子名称: 1,2-ETHANEDIOL, 6-[1-(2,2-difluoro-3-hydroxypropyl)-5-(4-fluorophenyl)-3-methyl-1H-pyrazol-4-yl]-2H-1,4-benzoxazin-3(4H)-one, Mineralocorticoid receptor
著者Sogabe, S, Habuka, N.
登録日2014-04-28
公開日2014-11-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Discovery of 6-[5-(4-fluorophenyl)-3-methyl-pyrazol-4-yl]-benzoxazin-3-one derivatives as novel selective nonsteroidal mineralocorticoid receptor antagonists
Bioorg.Med.Chem., 22, 2014
5H7G
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BU of 5h7g by Molmil
Crystal structure of the BCL6 BTB domain in complex with F1324
分子名称: B-cell lymphoma 6 protein, F1324 peptide, SULFATE ION
著者Sogabe, S, Ida, K, Lane, W, Snell, G.
登録日2016-11-18
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship.
Biochem. Biophys. Res. Commun., 482, 2017
5H7H
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BU of 5h7h by Molmil
Crystal structure of the BCL6 BTB domain in complex with F1324(10-13)
分子名称: 1,2-ETHANEDIOL, B-cell lymphoma 6 protein, F1324 peptide residues 10-13
著者Sogabe, S, Ida, K, Lane, W, Snell, G.
登録日2016-11-18
公開日2016-12-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship.
Biochem. Biophys. Res. Commun., 482, 2017
1EHL
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BU of 1ehl by Molmil
64M-2 ANTIBODY FAB COMPLEXED WITH D(5HT)(6-4)T
分子名称: 5'-(D(5HT)P*(6-4)T)-3', ANTI-(6-4) PHOTOPRODUCT ANTIBODY 64M-2 FAB (HEAVY CHAIN), ANTI-(6-4) PHOTOPRODUCT ANTIBODY 64M-2 FAB (LIGHT CHAIN)
著者Yokoyama, H, Mizutani, R, Satow, Y, Komatsu, Y, Ohtsuka, E, Nikaido, O.
登録日2000-02-21
公開日2001-02-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the 64M-2 antibody Fab fragment in complex with a DNA dT(6-4)T photoproduct formed by ultraviolet radiation.
J.Mol.Biol., 299, 2000
5H7U
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BU of 5h7u by Molmil
NMR structure of eIF3 36-163
分子名称: Eukaryotic translation initiation factor 3 subunit C
著者Nagata, T, Obayashi, E.
登録日2016-11-21
公開日2017-05-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.
Cell Rep, 18, 2017
5X9O
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BU of 5x9o by Molmil
Crystal structure of the BCL6 BTB domain in complex with Compound 1a
分子名称: 1,2-ETHANEDIOL, 5-[(2-chloranyl-4-nitro-phenyl)amino]-1,3-dihydrobenzimidazol-2-one, B-cell lymphoma 6 protein, ...
著者Sogabe, S, Ida, K, Lane, W, Snell, G.
登録日2017-03-08
公開日2017-08-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Discovery of a novel B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor by utilizing structure-based drug design
Bioorg. Med. Chem., 25, 2017
5X9P
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BU of 5x9p by Molmil
Crystal structure of the BCL6 BTB domain in complex with Compound 5
分子名称: 3-[[4-chloranyl-2-nitro-5-[(2-oxidanylidene-1,3-dihydrobenzimidazol-5-yl)amino]phenyl]amino]propanoic acid, B-cell lymphoma 6 protein
著者Sogabe, S, Ida, K, Lane, W, Snell, G.
登録日2017-03-08
公開日2017-08-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Discovery of a novel B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor by utilizing structure-based drug design
Bioorg. Med. Chem., 25, 2017
3WFF
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BU of 3wff by Molmil
Mineralocorticoid receptor ligand-binding domain with compound 2b
分子名称: 6-[4-(2,4-difluorophenyl)-5-oxo-2,5-dihydrofuran-3-yl]-2H-1,4-benzoxazin-3(4H)-one, Mineralocorticoid receptor, PHOSPHATE ION
著者Sogabe, S, Habuka, N.
登録日2013-07-19
公開日2013-08-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Design, synthesis, and structure-activity relationships of dihydrofuran-2-one and dihydropyrrol-2-one derivatives as novel benzoxazin-3-one-based mineralocorticoid receptor antagonists.
Bioorg.Med.Chem., 21, 2013
3WFG
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BU of 3wfg by Molmil
Mineralocorticoid receptor ligand-binding domain with compuond 2e
分子名称: 1,2-ETHANEDIOL, 6-[(2S)-4-(4-fluorophenyl)-2-methyl-5-oxo-2,5-dihydrofuran-3-yl]-2H-1,4-benzoxazin-3(4H)-one, Mineralocorticoid receptor
著者Sogabe, S, Habuka, N.
登録日2013-07-19
公開日2013-08-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Design, synthesis, and structure-activity relationships of dihydrofuran-2-one and dihydropyrrol-2-one derivatives as novel benzoxazin-3-one-based mineralocorticoid receptor antagonists.
Bioorg.Med.Chem., 21, 2013

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