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7RA8
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BU of 7ra8 by Molmil
SARS-CoV-2 S glycoprotein in complex with S2X259 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain Fab S2X259 Fab variable domain, ...
著者Veesler, D, Tortorici, M.A, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-06-30
公開日2021-08-04
最終更新日2021-09-15
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Broad sarbecovirus neutralization by a human monoclonal antibody.
Nature, 597, 2021
7RAL
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BU of 7ral by Molmil
SARS-CoV-2 S bound to S2X259 Fab (local refinement of the RBD/S2X259 variable domains)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2X259 Fab heavy chain, S2X259 Fab light chain, ...
著者Veesler, D, Tortorici, M.A, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-07-01
公開日2021-08-04
最終更新日2021-09-15
実験手法ELECTRON MICROSCOPY
主引用文献Broad sarbecovirus neutralization by a human monoclonal antibody.
Nature, 597, 2021
7RNJ
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BU of 7rnj by Molmil
S2P6 Fab fragment bound to the SARS-CoV/SARS-CoV-2 spike stem helix peptide
分子名称: Monoclonal antibody S2P6 Fab heavy chain, Monoclonal antibody S2P6 Fab light chain, SULFATE ION, ...
著者Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M, Sauer, M.M, Veesler, D.
登録日2021-07-29
公開日2021-08-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Broad betacoronavirus neutralization by a stem helix-specific human antibody.
Science, 373, 2021
5Y9L
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BU of 5y9l by Molmil
Human kallikrein 7 in complex with 1,3,6-trisubstituted 1,4-diazepane-7-one
分子名称: 3-[2-[(3Z,6R)-6-[(5-chloranyl-2-methoxy-phenyl)methyl]-3-(dimethylhydrazinylidene)-7-oxidanylidene-1,4-diazepan-1-yl]ethanoylamino]benzoic acid, CHLORIDE ION, Kallikrein-7
著者Sugawara, H.
登録日2017-08-25
公開日2017-11-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Discovery and structure-activity relationship study of 1,3,6-trisubstituted 1,4-diazepane-7-ones as novel human kallikrein 7 inhibitors
Bioorg. Med. Chem. Lett., 27, 2017
5YJK
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BU of 5yjk by Molmil
Human kallikrein 7 in complex with 1,4-diazepane-7-one 1-acetamide derivative
分子名称: (R)-2-(6-(5-chloro-2-methoxybenzyl)-3-(2,2-dimethylhydrazono)-7-oxo-1,4-diazepan-1-yl)-N-(3-(methylsulfonyl)phenyl)acetamide, CHLORIDE ION, Kallikrein-7
著者Sugawara, H.
登録日2017-10-11
公開日2017-12-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery and structure-activity relationship study of 1,3,6-trisubstituted 1,4-diazepane-7-ones as novel human kallikrein 7 inhibitors
Bioorg. Med. Chem. Lett., 27, 2017
2CZU
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BU of 2czu by Molmil
lipocalin-type prostaglandin D synthase
分子名称: Prostaglandin-H2 D-isomerase
著者Kumasaka, T, Irikura, D, Ago, H, Aritake, K, Yamamoto, M, Inoue, T, Miyano, M, Urade, Y, Hayaishi, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-17
公開日2006-10-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase.
J.Biol.Chem., 284, 2009
2CZT
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BU of 2czt by Molmil
lipocalin-type prostaglandin D synthase
分子名称: Prostaglandin-H2 D-isomerase
著者Kumasaka, T, Irikura, D, Ago, H, Aritake, K, Yamamoto, M, Inoue, T, Miyano, M, Urade, Y, Hayaishi, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-07-17
公開日2006-10-03
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of the catalytic mechanism operating in open-closed conformers of lipocalin type prostaglandin D synthase.
J.Biol.Chem., 284, 2009
5YSD
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BU of 5ysd by Molmil
Crystal structure of beta-1,2-glucooligosaccharide binding protein in complex with sophorotriose
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Lin1841 protein, MAGNESIUM ION, ...
著者Abe, K, Nakajima, M, Taguchi, H, Arakawa, T, Fushinobu, S.
登録日2017-11-14
公開日2018-05-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and thermodynamic insights into beta-1,2-glucooligosaccharide capture by a solute-binding protein inListeria innocua.
J. Biol. Chem., 293, 2018
5YSF
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BU of 5ysf by Molmil
Crystal structure of beta-1,2-glucooligosaccharide binding protein in complex with sophoropentaose
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Lin1841 protein, MAGNESIUM ION, ...
著者Abe, K, Nakajima, M, Taguchi, H, Arakawa, T, Fushinobu, S.
登録日2017-11-14
公開日2018-05-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and thermodynamic insights into beta-1,2-glucooligosaccharide capture by a solute-binding protein inListeria innocua.
J. Biol. Chem., 293, 2018
5YSE
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BU of 5yse by Molmil
Crystal structure of beta-1,2-glucooligosaccharide binding protein in complex with sophorotetraose
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Lin1841 protein, MAGNESIUM ION, ...
著者Abe, K, Nakajima, M, Taguchi, H, Arakawa, T, Fushinobu, S.
登録日2017-11-14
公開日2018-05-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and thermodynamic insights into beta-1,2-glucooligosaccharide capture by a solute-binding protein inListeria innocua.
J. Biol. Chem., 293, 2018
5YSB
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BU of 5ysb by Molmil
Crystal structure of beta-1,2-glucooligosaccharide binding protein in ligand-free form
分子名称: DI(HYDROXYETHYL)ETHER, Lin1841 protein, ZINC ION
著者Abe, K, Nakajima, M, Taguchi, H, Arakawa, T, Fushinobu, S.
登録日2017-11-13
公開日2018-05-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and thermodynamic insights into beta-1,2-glucooligosaccharide capture by a solute-binding protein inListeria innocua.
J. Biol. Chem., 293, 2018
4AIE
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BU of 4aie by Molmil
Structure of glucan-1,6-alpha-glucosidase from Lactobacillus acidophilus NCFM
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLUCAN 1,6-ALPHA-GLUCOSIDASE, ...
著者Fredslund, F, Navarro Poulsen, J.C, Lo Leggio, L.
登録日2012-02-09
公開日2012-08-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Enzymology and Structure of the Gh13_31 Glucan 1,6-Alpha-Glucosidase that Confers Isomaltooligosaccharide Utilization in the Probiotic Lactobacillus Acidophilus Ncfm.
J.Bacteriol., 194, 2012
5B0Q
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BU of 5b0q by Molmil
beta-1,2-Mannobiose phosphorylase from Listeria innocua - mannose complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Lin0857 protein, SULFATE ION, ...
著者Tsuda, T, Arakawa, T, Fushinobu, S.
登録日2015-11-02
公開日2015-12-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Characterization and crystal structure determination of beta-1,2-mannobiose phosphorylase from Listeria innocua
Febs Lett., 589, 2015
5B0R
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BU of 5b0r by Molmil
Beta-1,2-Mannobiose phosphorylase from Listeria innocua - beta-1,2-mannobiose complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Lin0857 protein, ...
著者Tsuda, T, Arakawa, T, Fushinobu, S.
登録日2015-11-02
公開日2015-12-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Characterization and crystal structure determination of beta-1,2-mannobiose phosphorylase from Listeria innocua
Febs Lett., 589, 2015
5B0P
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BU of 5b0p by Molmil
Beta-1,2-Mannobiose phosphorylase from Listeria innocua - glycerol complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Lin0857 protein, ...
著者Tsuda, T, Arakawa, T, Fushinobu, S.
登録日2015-11-02
公開日2015-12-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Characterization and crystal structure determination of beta-1,2-mannobiose phosphorylase from Listeria innocua
Febs Lett., 589, 2015
5B0S
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BU of 5b0s by Molmil
Beta-1,2-Mannobiose phosphorylase from Listeria innocua - beta-1,2-mannotriose complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Lin0857 protein, ...
著者Tsuda, T, Arakawa, T, Fushinobu, S.
登録日2015-11-02
公開日2015-12-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Characterization and crystal structure determination of beta-1,2-mannobiose phosphorylase from Listeria innocua
Febs Lett., 589, 2015
8IP2
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BU of 8ip2 by Molmil
Escherichia coli OpgG mutant-D361N with beta-1,2-glucan
分子名称: Glucans biosynthesis protein G, beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose-(1-2)-beta-D-glucopyranose
著者Motouchi, S, Nakajima, M.
登録日2023-03-13
公開日2024-03-13
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Identification of enzymatic functions of osmo-regulated periplasmic glucan biosynthesis proteins from Escherichia coli reveals a novel glycoside hydrolase family.
Commun Biol, 6, 2023
8IOX
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BU of 8iox by Molmil
Escherichia coli OpgD mutant-D388N
分子名称: Glucans biosynthesis protein D, alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose
著者Motouchi, S, Nakajima, M.
登録日2023-03-13
公開日2024-03-13
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Identification of enzymatic functions of osmo-regulated periplasmic glucan biosynthesis proteins from Escherichia coli reveals a novel glycoside hydrolase family.
Commun Biol, 6, 2023
8IP1
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BU of 8ip1 by Molmil
Escherichia coli OpgD mutant-D388N with beta-1,2-glucan
分子名称: DI(HYDROXYETHYL)ETHER, Glucans biosynthesis protein D, TRIETHYLENE GLYCOL, ...
著者Motouchi, S, Nakajima, M.
登録日2023-03-13
公開日2024-03-13
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Identification of enzymatic functions of osmo-regulated periplasmic glucan biosynthesis proteins from Escherichia coli reveals a novel glycoside hydrolase family.
Commun Biol, 6, 2023
5X6S
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BU of 5x6s by Molmil
Acetyl xylan esterase from Aspergillus awamori
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylxylan esterase A, ...
著者Komiya, D, Koseki, T, Fushinobu, S.
登録日2017-02-23
公開日2017-08-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure and Substrate Specificity Modification of Acetyl Xylan Esterase from Aspergillus luchuensis
Appl. Environ. Microbiol., 83, 2017
2BC1
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BU of 2bc1 by Molmil
Structural Analysis of Streptococcus pyogenes NADH oxidase: C44S Nox
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADH Oxidase
著者Boles, W.H, Mallett, T.C.
登録日2005-10-18
公開日2006-10-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural Analysis of Streptococcus pyogenes NADH Oxidase: Conformational Dynamics Involved in Formation of the C(4a)-Peroxyflavin Intermediate.
Biochemistry, 54, 2015
2BC0
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BU of 2bc0 by Molmil
Structural Analysis of Streptococcus pyogenes NADH oxidase: Wild-type Nox
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, NADH Oxidase
著者Boles, W.H, Mallett, T.C.
登録日2005-10-18
公開日2006-10-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of Streptococcus pyogenes NADH Oxidase: Conformational Dynamics Involved in Formation of the C(4a)-Peroxyflavin Intermediate.
Biochemistry, 54, 2015
2BCP
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BU of 2bcp by Molmil
Structural Analysis of Streptococcus pyogenes NADH oxidase: C44S Nox with Azide
分子名称: AZIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, NADH Oxidase
著者Boles, W.H, Mallett, T.C.
登録日2005-10-19
公開日2006-10-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Analysis of Streptococcus pyogenes NADH Oxidase: Conformational Dynamics Involved in Formation of the C(4a)-Peroxyflavin Intermediate.
Biochemistry, 54, 2015
2ZYB
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BU of 2zyb by Molmil
Crystal structure of phenylimidazo pyrazin 2 bound to the kinase domain of human LCK, (auto-phosphorylated on TYR394)
分子名称: N-(2,6-dimethylphenyl)-5-phenylimidazo[1,5-a]pyrazin-8-amine, Proto-oncogene tyrosine-protein kinase LCK, SULFATE ION
著者Tsuji, E.
登録日2009-01-19
公開日2009-02-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The importance of CH/pi hydrogen bonds in rational drug design: An ab initio fragment molecular orbital study to leukocyte-specific protein tyrosine (LCK) kinase
Bioorg.Med.Chem., 16, 2008
2ZM4
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BU of 2zm4 by Molmil
Crystal structure of imidazo quinoxaline 1 bound to the kinase domain of human LCK, activated form (auto-phosphorylated on TYR394)
分子名称: DIMETHYL SULFOXIDE, N-(2-chloro-6-methylphenyl)-8-[(3S)-3-methylpiperazin-1-yl]imidazo[1,5-a]quinoxalin-4-amine, Proto-oncogene tyrosine-protein kinase LCK, ...
著者Tsuji, E.
登録日2008-04-11
公開日2008-10-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The importance of CH/pi hydrogen bonds in rational drug design: An ab initio fragment molecular orbital study to leukocyte-specific protein tyrosine (LCK) kinase
Bioorg.Med.Chem., 16, 2008

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