7DYS
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7VMU
| Crystal Structure of SARS-CoV Spike Receptor-Binding Domain Complexed with Neutralizing Antibody | 分子名称: | Spike protein S1, scFv E4 | 著者 | Guo, Y, Wang, W, Jiao, P, Yang, H, Rao, Z, Cheng, G. | 登録日 | 2021-10-09 | 公開日 | 2021-11-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Antibody engineering improves neutralization activity against K417 spike mutant SARS-CoV-2 variants. Cell Biosci, 12, 2022
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7XKS
| Crystal structure of an alkaline pectate lyase from Bacillus clausii | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Pectate lyase | 著者 | Zhou, C, Zheng, Y.Y, Liu, W.D, Ma, Y. | 登録日 | 2022-04-20 | 公開日 | 2023-03-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structure of an Alkaline Pectate Lyase and Rational Engineering with Improved Thermo-Alkaline Stability for Efficient Ramie Degumming. Int J Mol Sci, 24, 2022
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7Y43
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7V63
| Structure of dimeric uPAR at low pH | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor | 著者 | Yuan, C, Huang, M. | 登録日 | 2021-08-19 | 公開日 | 2021-12-22 | 最終更新日 | 2022-04-06 | 実験手法 | X-RAY DIFFRACTION (2.906 Å) | 主引用文献 | Crystal structure and cellular functions of uPAR dimer Nat Commun, 13, 2022
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7D3M
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7D3K
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7D3R
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7D3L
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7Y9N
| an engineered 5-helix bundle derived from SARS-CoV-2 S2 in complex with HR2P | 分子名称: | SARS-coV-2 S2 subunit, Spike protein S2',5HB-H2 | 著者 | Lu, G.W, Lin, X, Guo, L.Y, Lin, S. | 登録日 | 2022-06-25 | 公開日 | 2022-08-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.885 Å) | 主引用文献 | An engineered 5-helix bundle derived from SARS-CoV-2 S2 pre-binds sarbecoviral spike at both serological- and endosomal-pH to inhibit virus entry. Emerg Microbes Infect, 11, 2022
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7FEI
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7FEJ
| Complex of FMDV A/AF/72 and bovine neutralizing scFv antibody R55 | 分子名称: | A/AF/72 VP1, A/AF/72 VP2, A/AF/72 VP3, ... | 著者 | He, Y, Li, K, Lou, Z. | 登録日 | 2021-07-20 | 公開日 | 2021-09-29 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | 主引用文献 | Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization. J.Virol., 95, 2021
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7YG3
| Crystal structure of HLA-B*13:01 | 分子名称: | ARG-GLN-ASP-ILE-LEU-ASP-LEU-TRP-ILE, Beta-2-microglobulin, MHC class I antigen | 著者 | Wang, H.S, Ouyang, S.Y. | 登録日 | 2022-07-11 | 公開日 | 2023-07-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Functional and structural characteristics of HLA-B*13:01-mediated specific T cells reaction in dapsone-induced drug hypersensitivity. J.Biomed.Sci., 29, 2022
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7EFR
| Structure of SARS-CoV-2 spike receptor-binding domain in complex with high affinity ACE2 mutant (T27W,N330Y) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Lu, G.W, Ye, F, Lin, X. | 登録日 | 2021-03-23 | 公開日 | 2021-11-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.494 Å) | 主引用文献 | S19W, T27W, and N330Y mutations in ACE2 enhance SARS-CoV-2 S-RBD binding toward both wild-type and antibody-resistant viruses and its molecular basis. Signal Transduct Target Ther, 6, 2021
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7EFP
| Structure of SARS-CoV-2 spike receptor-binding domain in complex with high affinity ACE2 mutant (S19W,N330Y) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Lu, G.W, Ye, F, Lin, X. | 登録日 | 2021-03-22 | 公開日 | 2021-11-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | 主引用文献 | S19W, T27W, and N330Y mutations in ACE2 enhance SARS-CoV-2 S-RBD binding toward both wild-type and antibody-resistant viruses and its molecular basis. Signal Transduct Target Ther, 6, 2021
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7DTD
| Voltage-gated sodium channel Nav1.1 and beta4 | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium channel protein type 1 subunit alpha, ... | 著者 | Yan, N, Pan, X, Li, Z, Huang, G. | 登録日 | 2021-01-04 | 公開日 | 2021-04-07 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Comparative structural analysis of human Na v 1.1 and Na v 1.5 reveals mutational hotspots for sodium channelopathies. Proc.Natl.Acad.Sci.USA, 118, 2021
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7EYA
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7EY0
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7EY5
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7EY4
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7EZV
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7XJF
| Crystal structure of 6MW3211 Fab in complex with CD47 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Wang, J, Wang, R, Jiao, S, Wang, S, Zhang, J, Zhang, M, Wang, M. | 登録日 | 2022-04-16 | 公開日 | 2023-05-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Blockade of dual immune checkpoint inhibitory signals with a CD47/PD-L1 bispecific antibody for cancer treatment. Theranostics, 13, 2023
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7W1S
| Crystal structure of SARS-CoV-2 spike receptor-binding domain in complex with neutralizing nanobody Nb-007 | 分子名称: | Nanobody Nb-007, Spike protein S1 | 著者 | Yang, J, Lin, S, Sun, H.L, Lu, G.W. | 登録日 | 2021-11-20 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | A Potent Neutralizing Nanobody Targeting the Spike Receptor-Binding Domain of SARS-CoV-2 and the Structural Basis of Its Intimate Binding. Front Immunol, 13, 2022
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7X5C
| Solution structure of Tetrahymena p75OB1-p50PBM | 分子名称: | Telomerase associated protein p50PBM, Telomerase-associated protein p75OB1 | 著者 | Wu, B, Tang, T, Xue, H.J, Wu, J, Lei, M. | 登録日 | 2022-03-04 | 公開日 | 2022-10-19 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Association of the CST complex and p50 in Tetrahymena is crucial for telomere maintenance Structure, 2022
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7VU8
| L7-Tir domain with bound ligand | 分子名称: | 2',3'- cyclic AMP, Flax rust resistance protein | 著者 | Tan, Y, Xu, C, Yu, D, Song, W, Wu, B, Schulze-Lefert, P, Chai, J. | 登録日 | 2021-11-01 | 公開日 | 2022-06-01 | 最終更新日 | 2022-07-06 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | TIR domains of plant immune receptors are 2',3'-cAMP/cGMP synthetases mediating cell death. Cell, 185, 2022
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