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8FRF
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BU of 8frf by Molmil
Homodimeric designed loop protein RBL7_C2_3
分子名称: MALONATE ION, RBL7_C2_3
著者Jude, K.M, Jiang, H, Baker, D, Garcia, K.C.
登録日2023-01-06
公開日2024-04-17
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献De novo design of buttressed loops for sculpting protein functions.
Nat.Chem.Biol., 20, 2024
8FRE
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BU of 8fre by Molmil
Designed loop protein RBL4
分子名称: 1,2-ETHANEDIOL, RBL4
著者Jude, K.M, Jiang, H, Baker, D, Garcia, K.C.
登録日2023-01-06
公開日2024-04-17
最終更新日2024-08-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献De novo design of buttressed loops for sculpting protein functions.
Nat.Chem.Biol., 20, 2024
1NUH
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BU of 1nuh by Molmil
The crystal structure of human phosphoglucose isomerase complexed with 5-phosphoarabinonate
分子名称: 5-PHOSPHOARABINONIC ACID, SULFATE ION, glucose phosphate isomerase
著者Davies, C.
登録日2003-01-31
公開日2003-02-11
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献The structure of human phosphoglucose isomerase complexed with a transition-state analogue.
Acta Crystallogr.,Sect.D, 59, 2003
8HW4
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BU of 8hw4 by Molmil
Cryo-EM structure of dehydroepiandrosterone sulfate-bound human ABC transporter ABCC3 in nanodiscs
分子名称: 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, ATP-binding cassette sub-family C member 3
著者Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z.
登録日2022-12-28
公開日2023-06-07
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
8HVH
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BU of 8hvh by Molmil
Cryo-EM structure of ABC transporter ABCC3
分子名称: ATP-binding cassette sub-family C member 3
著者Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z.
登録日2022-12-26
公開日2023-06-07
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
8HW2
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BU of 8hw2 by Molmil
Cryo-EM structure of beta-estradiol 17-(beta-D-glucuronide)-bound human ABC transporter ABCC3 in nanodiscs
分子名称: ATP-binding cassette sub-family C member 3, Estradiol-17beta-glucuronide
著者Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z.
登録日2022-12-28
公開日2023-06-07
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket.
Embo J., 42, 2023
5YPS
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BU of 5yps by Molmil
The structural basis of histone chaperoneVps75
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Chen, Y, Zhang, Y, Dou, Y, Wang, M, Xu, S, Jiang, H, Limper, A, Su, D.
登録日2017-11-03
公開日2018-11-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.097 Å)
主引用文献Structural basis for the acetylation of histone H3K9 and H3K27 mediated by the histone chaperone Vps75 inPneumocystis carinii.
Signal Transduct Target Ther, 4, 2019
6JDS
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BU of 6jds by Molmil
Crystal structure of truncated PRRSV nsp10 (helicase)
分子名称: PP1b, ZINC ION
著者Tang, C, Chen, Z.
登録日2019-02-02
公開日2020-02-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Helicase of Type 2 Porcine Reproductive and Respiratory Syndrome Virus Strain HV Reveals a Unique Structure.
Viruses, 12, 2020
6IXH
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BU of 6ixh by Molmil
Type VI secretion system membrane core complex
分子名称: Type VI Secretion System TssJ, Type VI Secretion System TssM
著者Yin, M, Yan, Z.
登録日2018-12-10
公開日2019-01-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Architecture of type VI secretion system membrane core complex.
Cell Res., 29, 2019
6JDU
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BU of 6jdu by Molmil
Crystal structure of PRRSV nsp10 (helicase)
分子名称: CALCIUM ION, PP1b, ZINC ION
著者Tang, C, Chen, Z.
登録日2019-02-02
公開日2020-02-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Helicase of Type 2 Porcine Reproductive and Respiratory Syndrome Virus Strain HV Reveals a Unique Structure.
Viruses, 12, 2020
5YU9
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BU of 5yu9 by Molmil
Crystal structure of EGFR 696-1022 T790M in complex with Ibrutinib
分子名称: 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one, CHLORIDE ION, Epidermal growth factor receptor
著者Yan, X.E, Yun, C.H.
登録日2017-11-21
公開日2017-12-27
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation.
Oncotarget, 7, 2016
6JCF
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BU of 6jcf by Molmil
Cryogenic structure of HIV-1 Integrase catalytic core domain by synchrotron
分子名称: CACODYLATE ION, Integrase
著者Park, J.H, Han, J, Kim, T.H, Yun, J.H, Lee, W.
登録日2019-01-28
公開日2019-07-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.153 Å)
主引用文献Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers.
Int J Mol Sci, 20, 2019
5Z3R
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BU of 5z3r by Molmil
Crystal Structure of Delta 5-3-Ketosteroid Isomerase from Mycobacterium sp.
分子名称: Steroid delta-isomerase
著者Cheng, X.Y, Peng, F, Yang, F, Huang, Y.Q, Su, Z.D.
登録日2018-01-08
公開日2018-01-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structure-based reconstruction of a Mycobacterium hypothetical protein into an active Delta5-3-ketosteroid isomerase.
Biochim Biophys Acta Proteins Proteom, 1867, 2019
6JDR
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BU of 6jdr by Molmil
Crystal structure of methylated PRRSV nsp10 (helicase)
分子名称: PP1b, SULFATE ION, ZINC ION
著者Deng, Z, Tang, C, Chen, Z.
登録日2019-02-02
公開日2020-02-05
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Helicase of Type 2 Porcine Reproductive and Respiratory Syndrome Virus Strain HV Reveals a Unique Structure.
Viruses, 12, 2020
1Q1M
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BU of 1q1m by Molmil
A Highly Efficient Approach to a Selective and Cell Active PTP1B inhibitors
分子名称: 5-{2-FLUORO-5-[3-(3-HYDROXY-2-METHOXYCARBONYL-PHENOXY)-PROPENYL]-PHENYL}-ISOXAZOLE-3-CARBOXYLIC ACID, Protein-tyrosine phosphatase, non-receptor type 1
著者Liu, G, Xin, Z, Pei, Z, Hajduk, P.J, Abad-Zapatero, C, Hutchins, C.W, Zhao, H, Lubben, T.H, Ballaron, S.J, Haasch, D.L, Kaszubska, W, Rondinone, C.M, Trevillyan, J.M, Jirousek, M.R.
登録日2003-07-22
公開日2003-09-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Fragment screening and assembly: a highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor.
J.Med.Chem., 46, 2003
6KII
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BU of 6kii by Molmil
photolyase from Arthrospira platensis
分子名称: 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, Deoxyribopyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Yan, H, Zhu, K.
登録日2019-07-18
公開日2020-07-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A newly identified photolyase from Arthrospira platensis possesses a unique methenyltetrahydrofolate chromophore-binding pattern.
Febs Lett., 594, 2020
5ZY5
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BU of 5zy5 by Molmil
spCOMT apo structure
分子名称: Probable catechol O-methyltransferase 1
著者Wang, Q, Xu, L.
登録日2018-05-22
公開日2019-05-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.295 Å)
主引用文献structural and functional investigations of spCOMT
To Be Published
5ZB5
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BU of 5zb5 by Molmil
The structural basis of histone chaperoneVps75
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, NAP family histone chaperone vps75
著者Chen, Y, Zhang, Y, Dou, Y, Wang, M, Xu, S, Jiang, H, Limper, A, Su, D.
登録日2018-02-09
公開日2019-02-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.299 Å)
主引用文献Structural basis for the acetylation of histone H3K9 and H3K27 mediated by the histone chaperone Vps75 inPneumocystis carinii.
Signal Transduct Target Ther, 4, 2019
6KY2
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BU of 6ky2 by Molmil
Crystal Structure of Arginine Kinase wild type from Daphnia magna
分子名称: Arginine kinase, PHOSPHATE ION
著者Park, J.H, Rao, Z, Kim, S.Y, Kim, D.S.
登録日2019-09-16
公開日2020-09-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Insight into Structural Aspects of Histidine 284 of Daphnia magna Arginine Kinase.
Mol.Cells, 43, 2020
6KVM
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BU of 6kvm by Molmil
Crystal structure of Chicken MHC Class II for 1.9 angstrom
分子名称: GLYCEROL, MHC class II alpha chain, MHC class II beta chain 2, ...
著者Zhang, L, Xia, C.
登録日2019-09-04
公開日2019-12-25
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.897 Å)
主引用文献A Newly Recognized Pairing Mechanism of the alpha- and beta-Chains of the Chicken Peptide-MHC Class II Complex.
J Immunol., 204, 2020
6KY3
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BU of 6ky3 by Molmil
Structure of arginine kinase H284A mutant
分子名称: ARGININE, Arginine kinase, PHOSPHATE ION, ...
著者Rao, Z, Park, J.H, Kim, S.Y, Kim, D.S.
登録日2019-09-16
公開日2020-09-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Insight into Structural Aspects of Histidine 284 of Daphnia magna Arginine Kinase.
Mol.Cells, 43, 2020
8JB4
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BU of 8jb4 by Molmil
lipopolysaccharide-binding domain-LBDB
分子名称: Antilipopolysaccharide factor D
著者Huang, J, Qin, Z.
登録日2023-05-08
公開日2024-03-13
最終更新日2025-03-19
実験手法SOLUTION NMR
主引用文献Machine learning and genetic algorithm-guided directed evolution for the development of antimicrobial peptides.
J Adv Res, 68, 2025
8K36
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BU of 8k36 by Molmil
Structure of the bacteriophage lambda tail tube
分子名称: Tail tube protein
著者Xiao, H, Tan, L, Cheng, L.P, Liu, H.R.
登録日2023-07-14
公開日2023-11-15
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly.
Plos Biol., 21, 2023
8K35
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Structure of the bacteriophage lambda tail tip complex
分子名称: IRON/SULFUR CLUSTER, Tail tip assembly protein I, Tail tip protein L, ...
著者Xiao, H, Tan, L, Cheng, L.P, Liu, H.R.
登録日2023-07-14
公開日2023-11-15
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly.
Plos Biol., 21, 2023
8K37
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Structure of the bacteriophage lambda neck
分子名称: Head-tail connector protein FII, Tail tube protein, Tail tube terminator protein
著者Xiao, H, Tan, L, Cheng, L.P, Liu, H.R.
登録日2023-07-14
公開日2023-11-15
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly.
Plos Biol., 21, 2023

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