6LHL
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![BU of 6lhl by Molmil](/molmil-images/mine/6lhl) | The cryo-EM structure of coxsackievirus A16 A-particle in complex with Fab 18A7 | 分子名称: | VP1 protein, VP2 protein, VP3 protein | 著者 | He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W. | 登録日 | 2019-12-09 | 公開日 | 2020-02-05 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. Cell Host Microbe, 27, 2020
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6LHB
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![BU of 6lhb by Molmil](/molmil-images/mine/6lhb) | The cryo-EM structure of coxsackievirus A16 A-particle | 分子名称: | VP1, VP2, VP3 | 著者 | He, M.Z, Xu, L.F, Zheng, Q.B, Zhu, R, Yin, Z.C, Cheng, T, Li, S.W. | 登録日 | 2019-12-07 | 公開日 | 2020-02-05 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Identification of Antibodies with Non-overlapping Neutralization Sites that Target Coxsackievirus A16. Cell Host Microbe, 27, 2020
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5NUH
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![BU of 5nuh by Molmil](/molmil-images/mine/5nuh) | |
5NUI
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![BU of 5nui by Molmil](/molmil-images/mine/5nui) | Crystal structure of SIVmac239 Nef in an ExxxLM endocytic sorting motif bound state | 分子名称: | Protein Nef, SER-GLN-ILE-LYS-ARG-LEU-LEU-SER | 著者 | Manrique, S, Horenkamp, F.A, Anand, K, Geyer, M. | 登録日 | 2017-04-30 | 公開日 | 2017-08-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Endocytic sorting motif interactions involved in Nef-mediated downmodulation of CD4 and CD3. Nat Commun, 8, 2017
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6WML
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![BU of 6wml by Molmil](/molmil-images/mine/6wml) | Human TLR8 bound to the potent agonist, GS-9688 (Selgantolimod) | 分子名称: | (2R)-2-[(2-amino-7-fluoropyrido[3,2-d]pyrimidin-4-yl)amino]-2-methylhexan-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 8, ... | 著者 | Appleby, T.C, Perry, J.K, Mish, M, Villasenor, A.G, Mackman, R.L. | 登録日 | 2020-04-21 | 公開日 | 2021-02-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of GS-9688 (Selgantolimod) as a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B. J.Med.Chem., 63, 2020
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6XUN
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![BU of 6xun by Molmil](/molmil-images/mine/6xun) | Ab 5b1 bound to CA19-9 | 分子名称: | GLYCEROL, Heavy chain, Light chain, ... | 著者 | Diskin, R, Borenstein-Katz, A. | 登録日 | 2020-01-20 | 公開日 | 2021-02-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies. J.Mol.Biol., 433, 2021
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6XTG
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![BU of 6xtg by Molmil](/molmil-images/mine/6xtg) | Ab 1116NS19.9 bound to CA19-9 | 分子名称: | Heavy chain, Light chain, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Diskin, R, Borenstein-Katz, A. | 登録日 | 2020-01-16 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies. J.Mol.Biol., 433, 2021
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6XUK
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6XUD
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![BU of 6xud by Molmil](/molmil-images/mine/6xud) | Apo Ab 1116NS19.9 | 分子名称: | Heavy chain, Light chain | 著者 | Diskin, R, Borenstein-Katz, A. | 登録日 | 2020-01-19 | 公開日 | 2021-01-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies. J.Mol.Biol., 433, 2021
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6XUL
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![BU of 6xul by Molmil](/molmil-images/mine/6xul) | Apo Ab 5b1 | 分子名称: | Heavy chain, Light chain | 著者 | Diskin, R, Borenstein-Katz, A. | 登録日 | 2020-01-20 | 公開日 | 2021-02-03 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Biomolecular Recognition of the Glycan Neoantigen CA19-9 by Distinct Antibodies. J.Mol.Biol., 433, 2021
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1QWF
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![BU of 1qwf by Molmil](/molmil-images/mine/1qwf) | C-SRC SH3 DOMAIN COMPLEXED WITH LIGAND VSL12 | 分子名称: | TYROSINE-PROTEIN KINASE TRANSFORMING PROTEIN SRC, VAL-SER-LEU-ALA-ARG-ARG-PRO-LEU-PRO-PRO-LEU-PRO | 著者 | Feng, S, Chiyoshi, K, Rickles, R.J, Schreiber, S.L. | 登録日 | 1995-11-09 | 公開日 | 1996-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands. Proc.Natl.Acad.Sci.USA, 92, 1995
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1QWE
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![BU of 1qwe by Molmil](/molmil-images/mine/1qwe) | C-SRC SH3 DOMAIN COMPLEXED WITH LIGAND APP12 | 分子名称: | ALA-PRO-PRO-LEU-PRO-PRO-ARG-ASN-ARG-PRO-ARG-LEU, TYROSINE-PROTEIN KINASE TRANSFORMING PROTEIN SRC | 著者 | Feng, S, Chiyoshi, K, Rickles, R.J, Schreiber, S.L. | 登録日 | 1995-11-09 | 公開日 | 1996-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Specific interactions outside the proline-rich core of two classes of Src homology 3 ligands. Proc.Natl.Acad.Sci.USA, 92, 1995
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6P6G
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![BU of 6p6g by Molmil](/molmil-images/mine/6p6g) | Co-crystal Structure of human SMYD3 with Isoxazole Amides Inhibitors | 分子名称: | 5-cyclopropyl-N-{1-[({trans-4-[(4,4,4-trifluorobutyl)amino]cyclohexyl}methyl)sulfonyl]piperidin-4-yl}-1,2-oxazole-3-carboxamide, GLYCEROL, Histone-lysine N-methyltransferase SMYD3, ... | 著者 | Elkins, P.A, Wang, L. | 登録日 | 2019-06-03 | 公開日 | 2020-01-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Discovery of Isoxazole Amides as Potent and Selective SMYD3 Inhibitors. Acs Med.Chem.Lett., 11, 2020
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6P6K
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6P7Z
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![BU of 6p7z by Molmil](/molmil-images/mine/6p7z) | |
6PAF
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6PXV
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![BU of 6pxv by Molmil](/molmil-images/mine/6pxv) | Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the extracellular region. | 分子名称: | Insulin, Insulin receptor | 著者 | Uchikawa, E, Choi, E, Shang, G.J, Yu, H.T, Bai, X.C. | 登録日 | 2019-07-27 | 公開日 | 2019-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex. Elife, 8, 2019
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6PYH
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![BU of 6pyh by Molmil](/molmil-images/mine/6pyh) | Cryo-EM structure of full-length IGF1R-IGF1 complex. Only the extracellular region of the complex is resolved. | 分子名称: | Insulin-like growth factor 1 receptor, Insulin-like growth factor I | 著者 | Li, J, Choi, E, Yu, H.T, Bai, X.C. | 登録日 | 2019-07-29 | 公開日 | 2019-10-23 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural basis of the activation of type 1 insulin-like growth factor receptor. Nat Commun, 10, 2019
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6PXW
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![BU of 6pxw by Molmil](/molmil-images/mine/6pxw) | Cryo-EM structure of full-length insulin receptor bound to 4 insulin. 3D refinement was focused on the top part of the receptor complex. | 分子名称: | Insulin, Insulin receptor | 著者 | Uchikawa, E, Choi, E, Shang, G.J, Yu, H.T, Bai, X.C. | 登録日 | 2019-07-28 | 公開日 | 2019-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex. Elife, 8, 2019
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6W6G
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6W6E
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6W6H
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6W6J
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6W6I
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8K6C
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![BU of 8k6c by Molmil](/molmil-images/mine/8k6c) | |