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ENHANCED PROTEIN THERMOSTABILITY FROM DESIGNED MUTATIONS THAT INTERACT WITH ALPHA-HELIX DIPOLES
分子名称:	T4 LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1989-05-01
公開日	1990-01-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Enhanced protein thermostability from designed mutations that interact with alpha-helix dipoles. Nature, 336, 1988

1L29

REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY
分子名称:	T4 LYSOZYME
著者	Bell, J.A, Dao-Pin, S, Matthews, B.W.
登録日	1989-05-01
公開日	1990-01-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Replacements of Pro86 in phage T4 lysozyme extend an alpha-helix but do not alter protein stability. Science, 239, 1988

1L53

STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Structural and thermodynamic analysis of the packing of two alpha-helices in bacteriophage T4 lysozyme. J.Mol.Biol., 221, 1991

1L27

REPLACEMENTS OF PRO86 IN PHAGE T4 LYSOZYME EXTEND AN ALPHA-HELIX BUT DO NOT ALTER PROTEIN STABILITY
分子名称:	T4 LYSOZYME
著者	Bell, J.A, Dao-Pin, S, Matthews, B.W.
登録日	1989-05-01
公開日	1990-01-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Replacements of Pro86 in phage T4 lysozyme extend an alpha-helix but do not alter protein stability. Science, 239, 1988

1L39

CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis. Biochemistry, 30, 1991

1L66

TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Heinz, D, Matthews, B.W.
登録日	1991-09-23
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence. Proc.Natl.Acad.Sci.USA, 89, 1992

1L73

MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Zhang, X, Matthews, B.W.
登録日	1991-09-23
公開日	1991-10-15
最終更新日	2020-07-22
実験手法	X-RAY DIFFRACTION (2.05 Å)
主引用文献	Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992

1L42

CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability. J.Mol.Biol., 221, 1991

1L46

CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability. J.Mol.Biol., 221, 1991

1L65

TOLERANCE OF T4 LYSOZYME TO MULTIPLE XAA (RIGHT ARROW) ALA SUBSTITUTIONS: A POLYALANINE ALPHA-HELIX CONTAINING TEN CONSECUTIVE ALANINES
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Heinz, D, Matthews, B.W.
登録日	1991-09-23
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence. Proc.Natl.Acad.Sci.USA, 89, 1992

1L70

MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Zhang, X, Matthews, B.W.
登録日	1991-09-23
公開日	1991-10-15
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992

1L75

MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Zhang, X, Matthews, B.W.
登録日	1991-09-23
公開日	1991-10-15
最終更新日	2020-07-22
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992

1L72

MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Zhang, X, Matthews, B.W.
登録日	1991-09-23
公開日	1991-10-15
最終更新日	2017-11-29
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992

1THL

Thermolysin complexed with a novel glutaramide derivative, n-(1-(2(r,s)-carboxy-4-phenylbutyl) cyclopentylcarbonyl)-(s)-tryptophan
分子名称:	CALCIUM ION, N-({1-[(2S)-2-carboxy-4-phenylbutyl]cyclopentyl}carbonyl)-L-tryptophan, THERMOLYSIN, ...
著者	Holland, D.R, Matthews, B.W.
登録日	1993-11-17
公開日	1994-01-31
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Inhibition of Thermolysin and Neutral Endopeptidase 24.11 By a Novel Glutaramide Derivative; X-Ray Structure Determination of the Thermolysin-Inhibitor Complex Biochemistry, 33, 1994

1TAS

CRYSTALLINE MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE EXISTS IN ONLY TWO CONFORMATIONS
分子名称:	2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID, ASPARTATE AMINOTRANSFERASE
著者	Hohenester, E, Jansonius, J.N.
登録日	1993-10-04
公開日	1994-01-31
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Crystalline mitochondrial aspartate aminotransferase exists in only two conformations. J.Mol.Biol., 236, 1994

1G1V

T4 LYSOZYME MUTANT C54T/C97A/I58T
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Quillin, M.L, Matthews, B.W.
登録日	2000-10-13
公開日	2001-05-09
最終更新日	2023-08-09
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme. Protein Sci., 10, 2001

1G1W

T4 LYSOZYME MUTANT C54T/C97A/Q105M
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Quillin, M.L, Matthews, B.W.
登録日	2000-10-13
公開日	2001-05-09
最終更新日	2023-08-09
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme. Protein Sci., 10, 2001

1L15

CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
分子名称:	T4 LYSOZYME
著者	Dao-Pin, S, Alber, T, Matthews, B.W.
登録日	1988-02-05
公開日	1988-04-16
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme. Nature, 330, 1987

1L06

CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
分子名称:	T4 LYSOZYME
著者	Dao-Pin, S, Wilson, K, Alber, T, Matthews, B.W.
登録日	1988-02-05
公開日	1988-04-16
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme. Nature, 330, 1987

1L13

CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
分子名称:	T4 LYSOZYME
著者	Dao-Pin, S, Alber, T, Matthews, B.W.
登録日	1988-02-05
公開日	1988-04-16
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme. Nature, 330, 1987

1L02

CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
分子名称:	T4 LYSOZYME
著者	Dao-Pin, S, Alber, T, Matthews, B.W.
登録日	1988-02-05
公開日	1988-04-16
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme. Nature, 330, 1987

1L09

CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
分子名称:	T4 LYSOZYME
著者	Dao-Pin, S, Bell, J, Alber, T, Matthews, B.W.
登録日	1988-02-05
公開日	1988-04-16
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme. Nature, 330, 1987

1L03

CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, T4 LYSOZYME
著者	Dao-Pin, S, Wilson, K, Alber, T, Matthews, B.W.
登録日	1988-02-05
公開日	1988-04-16
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme. Nature, 330, 1987

1L12

CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
分子名称:	T4 LYSOZYME
著者	Dao-Pin, S, Alber, T, Matthews, B.W.
登録日	1988-02-05
公開日	1988-04-16
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme. Nature, 330, 1987

1L16

STRUCTURAL ANALYSIS OF THE TEMPERATURE-SENSITIVE MUTANT OF BACTERIOPHAGE T4 LYSOZYME, GLYCINE 156 (RIGHT ARROW) ASPARTIC ACID
分子名称:	T4 LYSOZYME
著者	Gray, T.M, Matthews, B.W.
登録日	1988-02-05
公開日	1988-04-16
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structural analysis of the temperature-sensitive mutant of bacteriophage T4 lysozyme, glycine 156----aspartic acid. J.Biol.Chem., 262, 1987

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