2MS6
| Human Telomeric G-quadruplex DNA sequence (TTAGGGT)4 complexed with Flavonoid Quercetin | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, DNA_(5'-D(*TP*TP*AP*GP*GP*GP*T)-3') | 著者 | Kumar, A, Tawani, A. | 登録日 | 2014-07-24 | 公開日 | 2015-01-28 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Insight into the interaction of Flavonoids with Human Telomeric Sequence Sci Rep, 5, 2015
|
|
2MS5
| |
2NCQ
| |
2NCR
| |
2NYQ
| |
5XI1
| Structural Insight of Flavonoids binding to CAG repeat RNA that causes Huntington's Disease (HD) and Spinocerebellar Ataxia (SCAs) | 分子名称: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, RNA (5'-R(P*CP*CP*GP*CP*AP*GP*CP*GP*G)-3') | 著者 | Tawani, A, Mishra, S.K, Khan, E, Kumar, A. | 登録日 | 2017-04-25 | 公開日 | 2018-08-08 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Myricetin Reduces Toxic Level of CAG Repeats RNA in Huntington's Disease (HD) and Spino Cerebellar Ataxia (SCAs). ACS Chem. Biol., 13, 2018
|
|
4FNO
| Crystal structure of peptidyl t-RNA hydrolase from Pseudomonas aeruginosa at 2.2 Angstrom resolution | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Peptidyl-tRNA hydrolase | 著者 | Singh, A, Kumar, A, Arora, A, Singh, N, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2012-06-20 | 公開日 | 2012-07-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural and binding studies of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa provide a platform for the structure-based inhibitor design against peptidyl-tRNA hydrolase Biochem.J., 463, 2014
|
|
6KOY
| Crystal structure of two domain M1 Zinc metallopeptidase E323A mutant bound to L-tryptophan amino acid | 分子名称: | TRYPTOPHAN, ZINC ION, Zinc metalloprotease | 著者 | Agrawal, R, Kumar, A, Kumar, A, Makde, R.D. | 登録日 | 2019-08-13 | 公開日 | 2020-01-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural basis for the unusual substrate specificity of unique two-domain M1 metallopeptidase. Int.J.Biol.Macromol., 147, 2020
|
|
6EOJ
| PolyA polymerase module of the cleavage and polyadenylation factor (CPF) from Saccharomyces cerevisiae | 分子名称: | Polyadenylation factor subunit 2,Polyadenylation factor subunit 2, Protein CFT1, ZINC ION, ... | 著者 | Casanal, A, Kumar, A, Hill, C.H, Emsley, P, Passmore, L.A. | 登録日 | 2017-10-09 | 公開日 | 2017-11-15 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | 主引用文献 | Architecture of eukaryotic mRNA 3'-end processing machinery. Science, 358, 2017
|
|
8WT1
| Crystal structure of S9 carboxypeptidase from Geobacillus sterothermophilus | 分子名称: | ALANINE, CITRATE ANION, GLYCEROL, ... | 著者 | Chandravanshi, K, Kumar, A, Sen, C, Singh, R, Bhange, G.B, Makde, R.D. | 登録日 | 2023-10-17 | 公開日 | 2024-03-13 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure and solution scattering of Geobacillus stearothermophilus S9 peptidase reveal structural adaptations for carboxypeptidase activity. Febs Lett., 598, 2024
|
|
2G15
| Structural Characterization of autoinhibited c-Met kinase | 分子名称: | activated met oncogene | 著者 | Wang, W, Marimuthu, A, Tsai, J, Kumar, A, Krupka, H.I, Zhang, C, Powell, B, Suzuki, Y, Nguyen, H, Tabrizizad, M, Luu, C, West, B.L. | 登録日 | 2006-02-13 | 公開日 | 2006-03-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural characterization of autoinhibited c-Met kinase produced by coexpression in bacteria with phosphatase. Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
8ZN1
| Structure of erythrose-4-phosphate dehydrogenase from Acinetobacter baumannii at 3.00 A resolution | 分子名称: | Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION | 著者 | Viswanathan, V, Kumari, A, Singh, A, Kumar, A, Sharma, P, Chopra, S, Sharma, S, Raje, C.I, Singh, T.P. | 登録日 | 2024-05-25 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of erythrose-4-phosphate dehydrogenase from Acinetobacter baumannii at 3.00 A resolution To Be Published
|
|
8ZN4
| Crystal structure of Poly(ethylene glycol) stabilized erythrose-4-phosphate dehydrogenase from Acinetobacter baumannii at 2.30 A resolution | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, ... | 著者 | Viswanathan, V, Kumari, A, Singh, A, Kumar, A, Sharma, P, Chopra, S, Sharma, S, Raje, C.I, Singh, T.P. | 登録日 | 2024-05-25 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of Poly(ethylene glycol) stabilized erythrose-4-phosphate dehydrogenase from Acinetobacter baumannii at 2.30 A resolution To Be Published
|
|
6KRA
| |
8I7E
| Crystal structure of Glyceraldehyde 3-phosphate dehydrogenase from Salmonella typhi at 2.05A | 分子名称: | Glyceraldehyde-3-phosphate dehydrogenase | 著者 | Kumar, N, Dilawari, R, Chaubey, G.K, Modanwal, R, Talukdar, S, Dhiman, A, Chaudhary, S, Patidar, A, Kumar, A, Raje, C.I, Raje, M, Kumaran, S. | 登録日 | 2023-01-31 | 公開日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of Glyceraldehyde 3-phosphate dehydrogenase from Salmonella typhi at 2.05A To Be Published
|
|
5Z47
| Crystal structure of pyrrolidone carboxylate peptidase I with disordered loop A from Deinococcus radiodurans R1 | 分子名称: | DIMETHYL SULFOXIDE, Pyrrolidone-carboxylate peptidase | 著者 | Agrawal, R, Kumar, A, Kumar, A, Makde, R.D. | 登録日 | 2018-01-10 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structures of pyrrolidone-carboxylate peptidase I from Deinococcus radiodurans reveal the mechanism of L-pyroglutamate recognition. Acta Crystallogr D Struct Biol, 75, 2019
|
|
5Z48
| Crystal structure of pyrrolidone carboxylate peptidase I from Deinococcus radiodurans R1 bound to pyroglutamate | 分子名称: | DIMETHYL SULFOXIDE, PYROGLUTAMIC ACID, Pyrrolidone-carboxylate peptidase, ... | 著者 | Agrawal, R, Kumar, A, Kumar, A, Makde, R.D. | 登録日 | 2018-01-10 | 公開日 | 2019-01-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.551 Å) | 主引用文献 | Crystal structures of pyrrolidone-carboxylate peptidase I from Deinococcus radiodurans reveal the mechanism of L-pyroglutamate recognition. Acta Crystallogr D Struct Biol, 75, 2019
|
|
7F8S
| Pennisetum glaucum (Pearl millet) dehydroascorbate reductase (DHAR) with catalytic cysteine (Cy20) in sulphenic and sulfinic acid forms. | 分子名称: | Dehydroascorbate reductase, SULFATE ION | 著者 | Das, B.K, Kumar, A, Sreeshma, N.S, Arockiasamy, A. | 登録日 | 2021-07-02 | 公開日 | 2022-01-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Comparative kinetic analysis of ascorbate (Vitamin-C) recycling dehydroascorbate reductases from plants and humans. Biochem.Biophys.Res.Commun., 591, 2021
|
|
7XQ6
| The complex structure of mutant Mpro with inhibitor | 分子名称: | 3C-like proteinase nsp5, CHLORIDE ION | 著者 | Sahoo, P, Lenka, D.R, Kumar, A. | 登録日 | 2022-05-06 | 公開日 | 2023-03-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Detailed Insights into the Inhibitory Mechanism of New Ebselen Derivatives against Main Protease (M pro ) of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Acs Pharmacol Transl Sci, 6, 2023
|
|
7XQ7
| The complex structure of WT-Mpro | 分子名称: | 3C-like proteinase nsp5, SODIUM ION | 著者 | Sahoo, P, Lenka, D.R, Kumar, A. | 登録日 | 2022-05-06 | 公開日 | 2023-03-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Detailed Insights into the Inhibitory Mechanism of New Ebselen Derivatives against Main Protease (M pro ) of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Acs Pharmacol Transl Sci, 6, 2023
|
|
7W9G
| Complex structure of Mpro with ebselen-derivative inhibitor | 分子名称: | 3C-like proteinase nsp5, SELENIUM ATOM | 著者 | Sahoo, P, Kumar, A. | 登録日 | 2021-12-09 | 公開日 | 2022-12-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Detailed Insights into the Inhibitory Mechanism of New Ebselen Derivatives against Main Protease (M pro ) of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Acs Pharmacol Transl Sci, 6, 2023
|
|
7W9A
| |
6JBP
| Structure of MP-4 from Mucuna pruriens at 2.22 Angstroms | 分子名称: | Kunitz-type trypsin inhibitor-like 2 protein | 著者 | Jain, A, Shikhi, M, Kumar, A, Kumar, A, Nair, D.T, Salunke, D.M. | 登録日 | 2019-01-26 | 公開日 | 2020-01-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.217 Å) | 主引用文献 | The structure of MP-4 from Mucuna pruriens at 2.22 angstrom resolution. Acta Crystallogr.,Sect.F, 76, 2020
|
|
7XBJ
| Txp40, an insecticidal toxin protein from Xenorhabdus nematophila | 分子名称: | 40kDa insecticidal toxin | 著者 | Kinkar, O, Kumar, A, Prashar, A, Hire, R.S, Makde, R.D. | 登録日 | 2022-03-21 | 公開日 | 2023-03-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | The crystal structure of insecticidal protein Txp40 from Xenorhabdus nematophila reveals a two-domain unique binary toxin with homology to the toxin-antitoxin (TA) system. Insect Biochem.Mol.Biol., 164, 2023
|
|
7DF6
| Mouse Galectin-3 CRD in complex with novel tetrahydropyran-based thiodisaccharide mimic inhibitor | 分子名称: | (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-5-methoxy-6-[(3R,4R,5S)-4-oxidanyl-5-(4-pyrimidin-5-yl-1,2,3-triazol-1-yl)oxan-3-yl]sulfanyl-4-[4-[3,4,5-tris(fluoranyl)phenyl]-1,2,3-triazol-1-yl]oxan-3-ol, Galectin-3 | 著者 | Ghosh, K, Kumar, A. | 登録日 | 2020-11-06 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Synthesis, Structure-Activity Relationships, and In Vivo Evaluation of Novel Tetrahydropyran-Based Thiodisaccharide Mimics as Galectin-3 Inhibitors. J.Med.Chem., 64, 2021
|
|