7FU7
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7FU8
| Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(2-chloro-5-pyridin-4-ylphenyl)methylamino]-5-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one | 分子名称: | (8S)-2-({[2-chloro-5-(pyridin-4-yl)phenyl]methyl}amino)-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION | 著者 | Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. | 登録日 | 2023-02-08 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.718 Å) | 主引用文献 | Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
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7FU9
| Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(2-chloro-5-pyridin-4-ylphenyl)methylamino]-5-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one | 分子名称: | (8S)-2-({[2-chloro-5-(pyridin-4-yl)phenyl]methyl}amino)-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION | 著者 | Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. | 登録日 | 2023-02-08 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.668 Å) | 主引用文献 | Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
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7FUA
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7FUB
| Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(2-chloro-4-methylphenyl)-3-(pyridin-4-ylmethyl)benzimidazole-4-carboxylic acid | 分子名称: | (5M)-5-(2-chloro-4-methylphenyl)-1-[(pyridin-4-yl)methyl]-1H-benzimidazole-7-carboxylic acid, ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ... | 著者 | Leibrock, L, Benz, J, Groebke-Zbinden, K, Galley, G, Rudolph, M.G. | 登録日 | 2023-02-08 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.981 Å) | 主引用文献 | Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
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7FUF
| Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-benzyl-2-[[2-chloro-5-(1-methylpyrazol-3-yl)phenyl]methylamino]-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one | 分子名称: | (8S)-5-benzyl-2-({[(5P)-2-chloro-5-(1-methyl-1H-pyrazol-3-yl)phenyl]methyl}amino)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION | 著者 | Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. | 登録日 | 2023-02-08 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.919 Å) | 主引用文献 | Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
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7FUG
| Crystal Structure of human cyclic GMP-AMP synthase in complex with 5-benzyl-2-[[2-chloro-5-(1-methylpyrazol-3-yl)phenyl]methylamino]-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one | 分子名称: | (8S)-5-benzyl-2-({[(5P)-2-chloro-5-(1-methyl-1H-pyrazol-3-yl)phenyl]methyl}amino)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION | 著者 | Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. | 登録日 | 2023-02-08 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.106 Å) | 主引用文献 | Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
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7FUH
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7FUI
| Crystal Structure of human cyclic GMP-AMP synthase in complex with (Z)-2-cyano-N-[4-(3-fluorophenyl)-5-methylsulfonylpyrimidin-2-yl]-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide | 分子名称: | (2Z)-2-cyano-N-[(4P)-4-(3-fluorophenyl)-5-(methanesulfonyl)pyrimidin-2-yl]-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide, ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, ... | 著者 | Leibrock, L, Benz, J, Groebke-Zbinden, K, Rudolph, M.G. | 登録日 | 2023-02-08 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
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7FUK
| Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(2-chloro-4-methylphenyl)-3-(2-phenylethyl)benzimidazole-4-carboxylic acid | 分子名称: | (5M)-5-(2-chloro-4-methylphenyl)-1-(2-phenylethyl)-1H-benzimidazole-7-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION | 著者 | Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. | 登録日 | 2023-02-08 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.606 Å) | 主引用文献 | Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
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7FUL
| Crystal Structure of human cyclic GMP-AMP synthase in complex with 6-(2-chloro-4-methylphenyl)-3-[3-(methanesulfonamido)propyl]benzimidazole-4-carboxylic acid | 分子名称: | (5M)-5-(2-chloro-4-methylphenyl)-1-{3-[(methanesulfonyl)amino]propyl}-1H-benzimidazole-7-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION | 著者 | Leibrock, L, Benz, J, Groebke-Zbinden, K, Galley, G, Rudolph, M.G. | 登録日 | 2023-02-08 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.296 Å) | 主引用文献 | Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
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7FUM
| Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(4-benzylpiperazin-1-yl)methyl]-6-(2-chloro-4-methylphenyl)-1H-benzimidazole-4-carboxylic acid | 分子名称: | (5M)-2-[(4-benzylpiperazin-1-yl)methyl]-5-(2-chloro-4-methylphenyl)-1H-benzimidazole-7-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION | 著者 | Leibrock, L, Benz, J, Groebke-Zbinden, K, Galley, G, Rudolph, M.G. | 登録日 | 2023-02-08 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
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7FUN
| Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(4-benzylpiperazin-1-yl)methyl]-6-(2-chloro-4-methylphenyl)-1H-benzimidazole-4-carboxylic acid | 分子名称: | (5M)-2-[(4-benzylpiperazin-1-yl)methyl]-5-(2-chloro-4-methylphenyl)-1H-benzimidazole-7-carboxylic acid, CHLORIDE ION, Cyclic GMP-AMP synthase, ... | 著者 | Leibrock, L, Benz, J, Groebke-Zbinden, K, Galley, G, Rudolph, M.G. | 登録日 | 2023-02-08 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
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2C83
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2C84
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