7EGL
 
 | | Bicarbonate transporter complex SbtA-SbtB bound to HCO3- | | 分子名称: | BICARBONATE ION, Membrane-associated protein SbtB, SODIUM ION, ... | | 著者 | Fang, S, Huang, X, Zhang, X, Zhang, P. | | 登録日 | 2021-03-24 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Molecular mechanism underlying transport and allosteric inhibition of bicarbonate transporter SbtA.
Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
6KZ8
 | | Crystal structure of plant Phospholipase D alpha complex with phosphatidic acid | | 分子名称: | 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, CALCIUM ION, Phospholipase D alpha 1 | | 著者 | Li, J.X, Yu, F, Zhang, P. | | 登録日 | 2019-09-23 | | 公開日 | 2019-11-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.291 Å) | | 主引用文献 | Crystal structure of plant PLD alpha 1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D.
Cell Res., 30, 2020
|
|
7Z61
 | | Crystal structure of PI3Kgamma with a dihydropurinone inhibitor (compound 18) | | 分子名称: | 9-[(3~{R},4~{R})-4-fluoranylpyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | | 著者 | Goldberg, F.W, Ting, A.K.T, Schimpl, M. | | 登録日 | 2022-03-10 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.738 Å) | | 主引用文献 | Optimization of hERG and Pharmacokinetic Properties for Basic Dihydro-8 H -purin-8-one Inhibitors of DNA-PK.
Acs Med.Chem.Lett., 13, 2022
|
|
6KZ9
 | |
6L1G
 | |
7D0E
 | | Crystal structure of FIP200 Claw/p-CCPG1 FIR2 | | 分子名称: | 3-(2-hydroxyethyloxy)-2-[2-(2-hydroxyethyloxy)ethoxymethyl]-2-(2-hydroxyethyloxymethyl)propan-1-ol, Cell cycle progression protein 1 FIR2, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Zhou, Z.X, Pan, L.F. | | 登録日 | 2020-09-09 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation.
Nat Commun, 12, 2021
|
|
7CZG
 | | Crystal structure of FIP200 Claw domain apo form | | 分子名称: | DI(HYDROXYETHYL)ETHER, RB1-inducible coiled-coil protein 1 | | 著者 | Zhou, Z.X, Pan, L.F. | | 登録日 | 2020-09-08 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation.
Nat Commun, 12, 2021
|
|
7CZM
 | |
7XRW
 | | Solution structure of T. brucei RAP1 | | 分子名称: | Repressor activator protein 1 | | 著者 | Yang, X, Pan, X.H, Ji, Z.Y, Wong, K.B, Zhang, M.J, Zhao, Y.X. | | 登録日 | 2022-05-12 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The RRM-mediated RNA binding activity in T. brucei RAP1 is essential for VSG monoallelic expression.
Nat Commun, 14, 2023
|
|
7EA7
 | | crystal structure of NAP1 LIR in complex with GABARAP | | 分子名称: | Gamma-aminobutyric acid receptor-associated protein, NAP1_LIR motif | | 著者 | Fu, T, Pan, L. | | 登録日 | 2021-03-06 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
|
|
7EA2
 | | crystal structure of NAP1 FIR in complex with RB1CC1 Claw domain | | 分子名称: | 5-azacytidine-induced protein 2,RB1-inducible coiled-coil protein 1, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Fu, T, Pan, L. | | 登録日 | 2021-03-06 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52.
Sci Adv, 7, 2021
|
|
7EAA
 | |
4JF4
 | | OXA-23 meropenem complex | | 分子名称: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase | | 著者 | Smith, C.A, Vakulenko, S.B, Toth, M. | | 登録日 | 2013-02-27 | | 公開日 | 2013-09-25 | | 最終更新日 | 2013-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Structural Basis for Carbapenemase Activity of the OXA-23 beta-Lactamase from Acinetobacter baumannii.
Chem.Biol., 20, 2013
|
|
8Q0E
 | |
7YUJ
 | | Crystal structure of HOIL-1L(365-510) | | 分子名称: | DI(HYDROXYETHYL)ETHER, RanBP-type and C3HC4-type zinc finger-containing protein 1, ZINC ION | | 著者 | Xiao, L, Pan, L. | | 登録日 | 2022-08-17 | | 公開日 | 2023-08-30 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.865 Å) | | 主引用文献 | Mechanistic insights into the enzymatic activity of E3 ligase HOIL-1L and its regulation by the linear ubiquitin chain binding.
Sci Adv, 9, 2023
|
|
7YUI
 | |
5YDG
 | | Crystal structure of the Arabidopsis thaliana chloroplast RNA editing factors 2(MORF2) | | 分子名称: | Multiple organellar RNA editing factor 2, chloroplastic | | 著者 | Wang, X, Yang, J.Y, Wang, Y.L, Gao, Y.S. | | 登録日 | 2017-09-13 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | | 主引用文献 | Crystal structure of the chloroplast RNA editing factor MORF2
Biochem. Biophys. Res. Commun., 495, 2018
|
|
4OQR
 | | Structure of a CYP105AS1 mutant in complex with compactin | | 分子名称: | CYP105AS1, Mevastatin, Compactin, ... | | 著者 | Leys, D. | | 登録日 | 2014-02-10 | | 公開日 | 2015-02-18 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum.
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
6KI1
 | |
6KI2
 | |
6AHE
 | | Crystal structure of enoyl-ACP reductase from Acinetobacter baumannii in complex with NAD and AFN-1252 | | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADH], N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)propanamide, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Rani, S.T, Nataraj, V, Laxminarasimhan, A, Thomas, A, Krishnamurthy, N. | | 登録日 | 2018-08-17 | | 公開日 | 2019-08-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Ternary complex formation of AFN-1252 with Acinetobacter baumannii FabI and NADH: Crystallographic and biochemical studies.
Chem.Biol.Drug Des., 96, 2020
|
|
2ZND
 | | Crystal structure of Ca2+-free form of des3-20ALG-2 | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, PHOSPHATE ION, Programmed cell death protein 6, ... | | 著者 | Suzuki, H, Kawasaki, M, Inuzuka, T, Kakiuchi, T, Shibata, H, Wakatsuki, S, Maki, M. | | 登録日 | 2008-04-22 | | 公開日 | 2008-09-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism
Structure, 16, 2008
|
|
4OQS
 | | Crystal structure of CYP105AS1 | | 分子名称: | CYP105AS1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Leys, D. | | 登録日 | 2014-02-10 | | 公開日 | 2015-02-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum.
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
3SAS
 | | MUTM Slanted complex 4 with R112A mutation | | 分子名称: | 5'-D(*A*GP*GP*TP*AP*GP*AP*CP*TP*CP*GP*GP*AP*CP*GP*C)-3', 5'-D(*T*GP*CP*GP*TP*CP*CP*GP*AP*GP*(TX2) P*CP*TP*AP*CP*C)-3', DNA GLYCOSYLASE, ... | | 著者 | Qi, Y, Verdine, G.L. | | 登録日 | 2011-06-03 | | 公開日 | 2012-01-11 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Strandwise translocation of a DNA glycosylase on undamaged DNA.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
6CVW
 | |
