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5CEI
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BU of 5cei by Molmil
Crystal structure of CDK8:Cyclin C complex with compound 22
分子名称: 1,2-ETHANEDIOL, 4-(4-iodophenoxy)-N-methylthieno[2,3-c]pyridine-2-carboxamide, Cyclin-C, ...
著者Kiefer, J.R, Schneider, E.V, Maskos, K, Koehler, M.F.T.
登録日2015-07-06
公開日2016-02-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells.
Acs Med.Chem.Lett., 7, 2016
6GY9
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BU of 6gy9 by Molmil
Fucose-functionalized precision glycomacromolecules targeting human norovirus capsid protein
分子名称: 1,2-ETHANEDIOL, 2-(1H-1,2,3-triazol-1-yl)ethyl 6-deoxy-alpha-L-galactopyranoside, Capsid protein
著者Ruoff, K, Kilic, T, Hansman, G.S.
登録日2018-06-28
公開日2018-08-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Fucose-Functionalized Precision Glycomacromolecules Targeting Human Norovirus Capsid Protein.
Biomacromolecules, 19, 2018
6HQG
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BU of 6hqg by Molmil
Cytochrome P450-153 from Phenylobacterium zucineum
分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
著者Fiorentini, F, Mattevi, A.
登録日2018-09-25
公開日2018-12-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases.
Biochemistry, 57, 2018
6HQD
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BU of 6hqd by Molmil
Cytochrome P450-153 from Pseudomonas sp. 19-rlim
分子名称: Cytochrome P450, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Fiorentini, F, Mattevi, A.
登録日2018-09-24
公開日2018-12-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases.
Biochemistry, 57, 2018
6HQW
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BU of 6hqw by Molmil
Cytochrome P450-153 from Novosphingobium aromaticivorans
分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
著者Fiorentini, F, Mattevi, A.
登録日2018-09-25
公開日2018-12-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases.
Biochemistry, 57, 2018
4GMJ
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BU of 4gmj by Molmil
Structure of human NOT1 MIF4G domain co-crystallized with CAF1
分子名称: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 7, CHLORIDE ION, ...
著者Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
4GML
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BU of 4gml by Molmil
Crystal structure of human NOT1 MIF4G domain
分子名称: CCR4-NOT transcription complex subunit 1
著者Petit, P, Weichenrieder, O, Wohlbold, L, Izaurralde, E.
登録日2012-08-16
公開日2012-10-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res., 40, 2012
2LDY
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BU of 2ldy by Molmil
Solution structure of the RMM-CTD domains of human LINE-1 ORF1p
分子名称: ORF1 codes for a 40 kDa product
著者Coles, M, Truffault, V.
登録日2011-06-03
公開日2011-09-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Trimeric structure and flexibility of the L1ORF1 protein in human L1 retrotransposition.
Nat.Struct.Mol.Biol., 18, 2011
4OBQ
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BU of 4obq by Molmil
MAP4K4 in complex with inhibitor (compound 31), N-[3-(4-AMINOQUINAZOLIN-6-YL)-5-FLUOROPHENYL]-2-(PYRROLIDIN-1-YL)ACETAMIDE
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, Mitogen-activated protein kinase kinase kinase kinase 4, ...
著者Harris, S.F, Wu, P, Coons, M.
登録日2014-01-07
公開日2014-04-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Discovery of Selective 4-Amino-pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization.
J.Med.Chem., 57, 2014
4OBO
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BU of 4obo by Molmil
MAP4K4 in complex with inhibitor (compound 22), 6-(3-CHLOROPHENYL)QUINAZOLIN-4-AMINE
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(3-chlorophenyl)quinazolin-4-amine, Mitogen-activated protein kinase kinase kinase kinase 4, ...
著者Harris, S.F, Wu, P, Coons, M.
登録日2014-01-07
公開日2014-04-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of Selective 4-Amino-pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization.
J.Med.Chem., 57, 2014
4Q37
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BU of 4q37 by Molmil
Crystal structure of the hypothetical protein TM0182 Thermotoga maritima, N-terminal domain.
分子名称: PLATINUM (II) ION, Radical SAM protein
著者Hocker, B, Farias-Rico, J.A.
登録日2014-04-11
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Evolutionary relationship of two ancient protein superfolds.
Nat.Chem.Biol., 10, 2014
4OBP
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BU of 4obp by Molmil
MAP4K4 in complex with inhibitor (compound 29), 6-(2-FLUOROPYRIDIN-4-YL)PYRIDO[3,2-D]PYRIMIDIN-4-AMINE
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-fluoropyridin-4-yl)pyrido[3,2-d]pyrimidin-4-amine, MAGNESIUM ION, ...
著者Harris, S.F, Wu, P.
登録日2014-01-07
公開日2014-04-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Discovery of Selective 4-Amino-pyridopyrimidine Inhibitors of MAP4K4 Using Fragment-Based Lead Identification and Optimization.
J.Med.Chem., 57, 2014
5J8T
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BU of 5j8t by Molmil
NMR structure of Excalibur domain of CbpL
分子名称: CALCIUM ION, Choline binding protein
著者Pantoja-Uceda, D, Trevino, M.A, Bruix, M.
登録日2016-04-08
公開日2017-05-10
最終更新日2019-10-23
実験手法SOLUTION NMR
主引用文献Molecular Choline-bindind Protein L Involved in Pneumococcal Adhesion and Virulence through Exposed Excalibur domanin
To Be Published
6GV8
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BU of 6gv8 by Molmil
Characterization of extracellular matrix binding protein- (Embp)-mediated Staphylococcus epidermidis adherence to fibronectin
分子名称: Hyperosmolarity resistance protein Emb
著者Buettner, H, Rohde, H, Perbandt, M.
登録日2018-06-20
公開日2019-07-03
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.394 Å)
主引用文献A Giant Extracellular Matrix Binding Protein of Staphylococcus epidermidis Binds Surface-Immobilized Fibronectin via a Novel Mechanism.
Mbio, 11, 2020
4CNL
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BU of 4cnl by Molmil
Crystal structure of the Choline-binding domain of CbpL from Streptococcus pneumoniae
分子名称: CHOLINE ION, GLYCEROL, PUTATIVE PNEUMOCOCCAL SURFACE PROTEIN, ...
著者Gutierrez-Fernandez, J, Bartual, S.G, Hermoso, J.A.
登録日2014-01-23
公開日2015-02-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Modular Architecture and Unique Teichoic Acid Recognition Features of Choline-Binding Protein L (Cbpl) Contributing to Pneumococcal Pathogenesis.
Sci.Rep., 6, 2016
6GV5
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BU of 6gv5 by Molmil
Characterization of extracellular matrix binding protein- (Embp)-mediated Staphylococcus epidermidis adherence to fibronectin
分子名称: Hyperosmolarity resistance protein Emb
著者Buettner, H, Rohde, H, Perbandt, M.
登録日2018-06-20
公開日2019-07-03
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献A Giant Extracellular Matrix Binding Protein of Staphylococcus epidermidis Binds Surface-Immobilized Fibronectin via a Novel Mechanism.
Mbio, 11, 2020
6YA3
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BU of 6ya3 by Molmil
Crystal structure of PnrA from S. pneumoniae in complex with guanosine
分子名称: GUANOSINE, Lipoprotein, NICKEL (II) ION
著者Batuecas, M.T, Hermoso, J.A.
登録日2020-03-11
公開日2021-02-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Crystal Structure and Pathophysiological Role of the Pneumococcal Nucleoside-binding Protein PnrA.
J.Mol.Biol., 433, 2021
6YA4
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BU of 6ya4 by Molmil
Crystal structure of PnrA from S. pneumoniae in complex with cytidine
分子名称: 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Batuecas, M.T, Hermoso, J.A.
登録日2020-03-11
公開日2021-02-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure and Pathophysiological Role of the Pneumococcal Nucleoside-binding Protein PnrA.
J.Mol.Biol., 433, 2021
6YAB
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BU of 6yab by Molmil
Crystal structure of PnrA from S. pneumoniae in complex with uridine
分子名称: ACETATE ION, CACODYLATE ION, Lipoprotein, ...
著者Batuecas, M.T, Hermoso, J.A.
登録日2020-03-12
公開日2021-02-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure and Pathophysiological Role of the Pneumococcal Nucleoside-binding Protein PnrA.
J.Mol.Biol., 433, 2021
6Y9U
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BU of 6y9u by Molmil
Crystal structure of PnrA from S. pneumoniae in complex with adenosine
分子名称: ACETATE ION, ADENOSINE, Lipoprotein, ...
著者Batuecas, M.T, Hermoso, J.A.
登録日2020-03-10
公開日2021-02-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure and Pathophysiological Role of the Pneumococcal Nucleoside-binding Protein PnrA.
J.Mol.Biol., 433, 2021
6YAG
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BU of 6yag by Molmil
Crystal structure of PnrA from S. pneumoniae in complex with thymidine
分子名称: ACETATE ION, Lipoprotein, NICKEL (II) ION, ...
著者Batuecas, M.T, Hermoso, J.A.
登録日2020-03-12
公開日2021-02-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal Structure and Pathophysiological Role of the Pneumococcal Nucleoside-binding Protein PnrA.
J.Mol.Biol., 433, 2021
4D0Y
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BU of 4d0y by Molmil
Crystal structure of DacB from Streptococcus pneumoniae D39
分子名称: DACB, PHOSPHATE ION, ZINC ION
著者Gutierrez-Fernandez, J, Hermoso, J.A.
登録日2014-04-30
公開日2014-08-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the Pneumococcal L,D-Carboxypeptidase Dacb and Pathophysiological Effects of Disabled Cell Wall Hydrolases Daca and Dacb.
Mol.Microbiol., 93, 2014

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