2WNP
| M-ficolin mutant Y271F | 分子名称: | CALCIUM ION, FICOLIN-1, ISOPROPYL ALCOHOL | 著者 | Gout, E, Garlatti, V, Smith, D.F, Lacroix, M, Dumestre-Perard, C, Lunardi, T, Arlaud, G.J, Gaboriaud, C, Thielens, N.M. | 登録日 | 2009-07-16 | 公開日 | 2009-12-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Carbohydrate Recognition Properties of Human Ficolins: Glycan Array Screening Reveals the Sialic Acid Binding Specificity of M-Ficolin. J.Biol.Chem., 285, 2010
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1E0D
| UDP-N-Acetylmuramoyl-L-Alanine:D-Glutamate Ligase | 分子名称: | SULFATE ION, UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE | 著者 | Fanchon, E, Bertrand, J, Chantalat, L, Dideberg, O. | 登録日 | 2000-03-24 | 公開日 | 2000-06-09 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | "Open" Structures of Murd: Domain Movements and Structural Similarities with Folylpolyglutamate Synthetase. J.Mol.Biol., 301, 2000
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5W4L
| Crystal structure of the non-neutralizing and ADCC-potent C11-like antibody N12-i3 in complex with HIV-1 clade A/E gp120, the CD4 mimetic M48U1, and the antibody N5-i5. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody N12-i3 Fab heavy chain, Antibody N12-i3 light chain, ... | 著者 | Tolbert, W.D, Gohain, N, Pazgier, M. | 登録日 | 2017-06-12 | 公開日 | 2017-11-15 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Targeting the Late Stage of HIV-1 Entry for Antibody-Dependent Cellular Cytotoxicity: Structural Basis for Env Epitopes in the C11 Region. Structure, 25, 2017
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4R4B
| Crystal structure of the anti-hiv-1 antibody 2.2c | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB 2.2C HEAVY CHAIN, FAB 2.2C LIGHT CHAIN, ... | 著者 | McLellan, J.S, Acharya, P, Huang, C.-C, Robinson, J, Kwong, P.D. | 登録日 | 2014-08-19 | 公開日 | 2014-09-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
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4R4H
| Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 Env gp120 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c, Heavy chain, ... | 著者 | Mclellan, J, Acharya, P, Huang, C.-C, Kwong, P.D. | 登録日 | 2014-08-19 | 公開日 | 2014-09-17 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (4.28 Å) | 主引用文献 | Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
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4RFE
| Crystal structure of ADCC-potent ANTI-HIV-1 Rhesus macaque antibody JR4 Fab | 分子名称: | CHLORIDE ION, Fab heavy chain of ADCC-potent anti-HIV-1 antibody JR4, Fab light chain of ADCC-potent anti-HIV-1 antibody JR4, ... | 著者 | Wu, X, Gohain, N, Tolbert, W.D, Pazgier, M. | 登録日 | 2014-09-25 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1. J.Virol., 89, 2015
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4R4N
| Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, Antibody 2.2c heavy CHAIN, ... | 著者 | Acharya, P, Louder, R, Kwong, P.D. | 登録日 | 2014-08-19 | 公開日 | 2014-11-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.56 Å) | 主引用文献 | Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
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4RFO
| Crystal structure of the ADCC-Potent Antibody N60-I3 Fab in complex with HIV-1 Clade A/E gp120 and M48u1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 clade A/E gp120, N60-i3 Fab heavy chain, ... | 著者 | Tolbert, W.D, Gohain, N, Pazgier, M. | 登録日 | 2014-09-26 | 公開日 | 2015-07-15 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1. J.Virol., 89, 2015
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4R4F
| Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 YU2 gp120 | 分子名称: | (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, ... | 著者 | Acharya, P, Kwong, P.D. | 登録日 | 2014-08-19 | 公開日 | 2014-09-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.514 Å) | 主引用文献 | Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
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4RFN
| Crystal structure of ADCC-potent Rhesus macaque ANTIBODY JR4 in complex with HIV-1 CLADE A/E GP120 and M48 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB HEAVY CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4, FAB LIGHT CHAIN OF ADCC ANTI-HIV-1 ANTIBODY JR4, ... | 著者 | Gohain, N, Tolbert, W.D, Pazgier, M. | 登録日 | 2014-09-26 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Cocrystal Structures of Antibody N60-i3 and Antibody JR4 in Complex with gp120 Define More Cluster A Epitopes Involved in Effective Antibody-Dependent Effector Function against HIV-1. J.Virol., 89, 2015
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3DEM
| CUB1-EGF-CUB2 domain of HUMAN MASP-1/3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement factor MASP-3 | 著者 | Gaboriaud, C. | 登録日 | 2008-06-10 | 公開日 | 2008-07-01 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins J.Biol.Chem., 283, 2008
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1UAG
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4K2Y
| Crystal Structure of Human Chymase in Complex with Fragment Inhibitor 6-chloro-1,3-dihydro-2H-indol-2-one | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-chloro-1,3-dihydro-2H-indol-2-one, Chymase, ... | 著者 | Collins, B.K, Padyana, A.K. | 登録日 | 2013-04-09 | 公開日 | 2013-05-29 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery of Potent, Selective Chymase Inhibitors via Fragment Linking Strategies. J.Med.Chem., 56, 2013
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4JZZ
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4JZW
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4K0A
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8B0Q
| Deinococcus radiodurans UvrC C-terminal half | 分子名称: | UvrABC system protein C | 著者 | Timmins, J, Stelter, M. | 登録日 | 2022-09-08 | 公開日 | 2023-02-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and functional insights into the activation of the dual incision activity of UvrC, a key player in bacterial NER. Nucleic Acids Res., 51, 2023
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2J64
| H-ficolin | 分子名称: | CALCIUM ION, FICOLIN-3 | 著者 | Garlatti, V, Gaboriaud, C. | 登録日 | 2006-09-25 | 公開日 | 2007-01-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins. Embo J., 26, 2007
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2J3U
| L-ficolin complexed to galactose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Garlatti, V, Gaboriaud, C. | 登録日 | 2006-08-23 | 公開日 | 2007-01-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins. Embo J., 26, 2007
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2J0G
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2J3F
| L-ficolin complexed to N-acetyl-D-galactosamine | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Garlatti, V, Gaboriaud, C. | 登録日 | 2006-08-21 | 公開日 | 2007-01-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins. Embo J., 26, 2007
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2J60
| H-ficolin complexed to D-fucose | 分子名称: | ACETATE ION, CALCIUM ION, FICOLIN-3, ... | 著者 | Garlatti, V, Gaboriaud, C. | 登録日 | 2006-09-21 | 公開日 | 2007-01-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins. Embo J., 26, 2007
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2J1G
| L-ficolin complexed to N-acetyl-cystein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | 著者 | Garlatti, V, Gaboriaud, C. | 登録日 | 2006-08-11 | 公開日 | 2007-01-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins. Embo J., 26, 2007
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2J2P
| L-ficolin complexed to N-acetyl-cystein (150mM) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FICOLIN-2, ... | 著者 | Garlatti, V, Gaboriaud, C. | 登録日 | 2006-08-17 | 公開日 | 2007-01-23 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins. Embo J., 26, 2007
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3S0N
| Crystal Structure of Human Chymase with Benzimidazolone Inhibitor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-{3-[(4-methyl-1-benzothiophen-3-yl)methyl]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}butanoic acid, Chymase, ... | 著者 | Qian, K.C, Farrow, N.A, Padyana, A.K. | 登録日 | 2011-05-13 | 公開日 | 2011-07-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Benzimidazolone as potent chymase inhibitor: Modulation of reactive metabolite formation in the hydrophobic (P(1)) region. Bioorg.Med.Chem.Lett., 21, 2011
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