7EQK
 
 | | Structural and mechanistic studies of a novel non-heme iron epimerase/lyase and its utilization in chemoselective synthesis. | | 分子名称: | (E)-3-(1H-indol-3-yl)-2-oxidanyl-but-2-enoic acid, 1-(1~{H}-indol-3-yl)ethanone, Cupin domain-containing protein, ... | | 著者 | Li, T.L, Li, Y.S, Chen, M.H. | | 登録日 | 2021-05-03 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.04001021 Å) | | 主引用文献 | Structural and Mechanistic Bases for StnK3 and Its Mutant-Mediated Lewis-Acid-Dependent Epimerization and Retro-Aldol Reactions.
Acs Catalysis, 12, 2022
|
|
7EU6
 | |
7V4M
 | |
7V4O
 | | Unique non-heme hydroxylase in biosynthesis of nucleoside antibiotic pathway uncover mechanism of reaction | | 分子名称: | 3,6,9,12,15-PENTAOXAHEPTADECANE, Beta-hydroxylase | | 著者 | Li, T.L, Saeid, M.Z. | | 登録日 | 2021-08-13 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | beta-Hydroxylation of alpha-amino-beta-hydroxylbutanoyl-glycyluridine catalyzed by a nonheme hydroxylase ensures the maturation of caprazamycin
Commun Chem, 5, 2022
|
|
7V4N
 | |
7V4P
 | |
7V4F
 | |
7VYY
 | |
7VZA
 | |
7VZ6
 | |
7XQA
 | | Orf1-glycine complex | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCINE, N-formimidoyl fortimicin A synthase | | 著者 | Wang, Y.L, Li, T.L. | | 登録日 | 2022-05-07 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry.
Nat Commun, 14, 2023
|
|
5ZZS
 | | The crystal structure of Mandelate oxidase with benzoic acid | | 分子名称: | 4-hydroxymandelate oxidase, BENZOIC ACID, FLAVIN MONONUCLEOTIDE | | 著者 | Li, T.L, Lin, K.H. | | 登録日 | 2018-06-04 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.398 Å) | | 主引用文献 | Biochemical and structural explorations of alpha-hydroxyacid oxidases reveal a four-electron oxidative decarboxylation reaction.
Acta Crystallogr D Struct Biol, 75, 2019
|
|
5ZZY
 | |
6A01
 | | The crystal structure of Mandelate oxidase Y128F with 3,3-difluoro-2,2-dihydroxy-3-phenylpropionic acid | | 分子名称: | 3,3-difluoro-2,2-dihydroxy-3-phenylpropanoic acid, 4-hydroxymandelate oxidase, FLAVIN MONONUCLEOTIDE | | 著者 | Li, T.L, Lin, K.H. | | 登録日 | 2018-06-05 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.868 Å) | | 主引用文献 | Structural and chemical trapping of flavin-oxide intermediates reveals substrate-directed reaction multiplicity.
Protein Sci., 29, 2020
|
|
6A0G
 | |
6A23
 | | Mandelate oxidase mutant-Y128F with the N5-benzyl-FMN adduct | | 分子名称: | 1-[5-(benzenecarbonyl)-7,8-dimethyl-2,4-dioxo-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-1-deoxy-5-O-phosphono-D-ribitol, 4-hydroxymandelate oxidase, BENZOYL-FORMIC ACID, ... | | 著者 | Li, T.L, Lin, K.H. | | 登録日 | 2018-06-08 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The flavin mononucleotide cofactor in alpha-hydroxyacid oxidases exerts its electrophilic/nucleophilic duality in control of the substrate-oxidation level.
Acta Crystallogr D Struct Biol, 75, 2019
|
|
6A1A
 | | Mandelate oxidase mutant-Y128F with 4-hydroxymandelic acid | | 分子名称: | (2S)-hydroxy(4-hydroxyphenyl)ethanoic acid, 4-hydroxymandelate oxidase, FLAVIN MONONUCLEOTIDE | | 著者 | Li, T.L, Lin, K.H. | | 登録日 | 2018-06-07 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Biochemical and structural explorations of alpha-hydroxyacid oxidases reveal a four-electron oxidative decarboxylation reaction.
Acta Crystallogr D Struct Biol, 75, 2019
|
|
6A1N
 | | Mandelate oxidase mutant-Y128F with (2R,3S)-3-fluoro-2-hydroxy-3-phenylpropanoic acid | | 分子名称: | (2R,3S)-3-fluoro-2-hydroxy-3-phenylpropanoic acid, 4-hydroxymandelate oxidase, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Li, T.L, Lin, K.H. | | 登録日 | 2018-06-07 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.421 Å) | | 主引用文献 | Structural and chemical trapping of flavin-oxide intermediates reveals substrate-directed reaction multiplicity.
Protein Sci., 29, 2020
|
|
6A1W
 | | Mandelate oxidase with the enoyl FMN epoxide adduct | | 分子名称: | 1-[(1aR,11R)-11-acetyl-8,9-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]oxazireno[3,2-e]pteridin-11-ium-6(2H)-yl]-1-deoxy-5-O-phosphono-D-ribitol, 4-hydroxymandelate oxidase, MAGNESIUM ION | | 著者 | Li, T.L, Lin, K.H. | | 登録日 | 2018-06-08 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and chemical trapping of flavin-oxide intermediates reveals substrate-directed reaction multiplicity.
Protein Sci., 29, 2020
|
|
5ZZT
 | |
5ZZZ
 | |
6A21
 | | Mandelate oxidase mutant-Y128F with the N5-malonyl-FMN adduct | | 分子名称: | 3-[7,8-dimethyl-2,4-bis(oxidanylidene)-10-[(2S,3S,4R)-2,3,4-tris(oxidanyl)-5-phosphonooxy-pentyl]-1H-benzo[g]pteridin-5-yl]-3-oxidanylidene-propanoic acid, 4-hydroxymandelate oxidase | | 著者 | Li, T.L, Lin, K.H. | | 登録日 | 2018-06-08 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | | 主引用文献 | The flavin mononucleotide cofactor in alpha-hydroxyacid oxidases exerts its electrophilic/nucleophilic duality in control of the substrate-oxidation level.
Acta Crystallogr D Struct Biol, 75, 2019
|
|
6A4H
 | | Mandelate oxidase mutant-Y128F with the peroxide FMN adduct | | 分子名称: | 4-hydroxymandelate oxidase, [(2~{R},3~{S},4~{S})-5-[(4~{a}~{S})-4~{a}-(dioxidanyl)-7,8-dimethyl-2,4-bis(oxidanylidene)-5~{H}-benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentyl] dihydrogen phosphate | | 著者 | Li, T.L, Lin, K.H. | | 登録日 | 2018-06-19 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural and chemical trapping of flavin-oxide intermediates reveals substrate-directed reaction multiplicity.
Protein Sci., 29, 2020
|
|
5ZZQ
 | |
6A11
 | | Mandelate oxidase mutant-Y128F with phenylpyruvic acid | | 分子名称: | 3-PHENYLPYRUVIC ACID, 4-hydroxymandelate oxidase, FLAVIN MONONUCLEOTIDE | | 著者 | Li, T.L, Lin, K.H. | | 登録日 | 2018-06-06 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Biochemical and structural explorations of alpha-hydroxyacid oxidases reveal a four-electron oxidative decarboxylation reaction.
Acta Crystallogr D Struct Biol, 75, 2019
|
|
