7OWC
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7XRQ
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7UVJ
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![BU of 7uvj by Molmil](/molmil-images/mine/7uvj) | Rationally Designed ED1 Epitope-Scaffold Immunogen for SARS-CoV-2 | 分子名称: | ACETATE ION, Apolipoprotein E, DI(HYDROXYETHYL)ETHER, ... | 著者 | Yennawar, N.H, Vishweshwaraiah, Y.L, Dokholyan, N.V. | 登録日 | 2022-05-02 | 公開日 | 2022-10-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Adaptation-proof SARS-CoV-2 vaccine design. Adv Funct Mater, 32, 2022
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6AIM
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![BU of 6aim by Molmil](/molmil-images/mine/6aim) | Cab2 mutant H337A complex with phosphopantothenate-cysteine | 分子名称: | N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl-L-cysteine, Phosphopantothenate--cysteine ligase CAB2 | 著者 | Zheng, P, Zhu, Z. | 登録日 | 2018-08-24 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae. J. Mol. Biol., 431, 2019
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6AI9
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![BU of 6ai9 by Molmil](/molmil-images/mine/6ai9) | Cab2 mutant-H337A complex with phosphopantothenate | 分子名称: | N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanine, Phosphopantothenate--cysteine ligase CAB2 | 著者 | Zheng, P, Zhu, Z. | 登録日 | 2018-08-22 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae. J. Mol. Biol., 431, 2019
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6H5O
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6AI8
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![BU of 6ai8 by Molmil](/molmil-images/mine/6ai8) | Cab2 mutant-H337A | 分子名称: | GLYCEROL, Phosphopantothenate--cysteine ligase CAB2, SULFATE ION | 著者 | Zheng, P, Zhu, Z. | 登録日 | 2018-08-22 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae. J. Mol. Biol., 431, 2019
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5ELQ
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5EM9
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6AIP
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![BU of 6aip by Molmil](/molmil-images/mine/6aip) | Cab2 mutant-H337A complex with phosphopantothenoylcystine | 分子名称: | (5R,12R,17R)-17-amino-12-carboxy-1,1,5-trihydroxy-4,4-dimethyl-6,10-dioxo-2-oxa-14,15-dithia-7,11-diaza-1-phosphaoctadecan-18-oic acid 1-oxide (non-preferred name), Phosphopantothenate--cysteine ligase CAB2 | 著者 | Zheng, P, Zhu, Z. | 登録日 | 2018-08-24 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae. J. Mol. Biol., 431, 2019
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6AIK
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![BU of 6aik by Molmil](/molmil-images/mine/6aik) | Cab2 mutant H337A complex with phosphopantothenoyl-CMP | 分子名称: | PHOSPHORIC ACID MONO-[3-(3-{[5-(4-AMINO-2-OXO-2H-PYRIMIDIN-1-YL)-3,4- DIHYDROXY-TETRAHYDRO-FURAN-2- YLMETHOXY]-HYDROXY-PHOSPHORYLOXY}-3-OXO-PROPYLCARBAMOYL)-3-HYDROXY-2,2- DIMETHYL-PROPYL] ESTER, Phosphopantothenate--cysteine ligase CAB2 | 著者 | Zheng, P, Zhu, Z. | 登録日 | 2018-08-24 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae. J. Mol. Biol., 431, 2019
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3RO2
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![BU of 3ro2 by Molmil](/molmil-images/mine/3ro2) | Structures of the LGN/NuMA complex | 分子名称: | G-protein-signaling modulator 2, GLYCEROL, peptide of Nuclear mitotic apparatus protein 1 | 著者 | Shang, Y, Wei, Z. | 登録日 | 2011-04-25 | 公開日 | 2012-03-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and G[alpha]i/LGN/NuMA pathways Mol.Cell, 43, 2011
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6S1F
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![BU of 6s1f by Molmil](/molmil-images/mine/6s1f) | Structure of the kinase domain of human RIPK2 in complex with the inhibitor CSLP3 | 分子名称: | Receptor-interacting serine/threonine-protein kinase 2, ~{N}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamide | 著者 | Pinkas, D.M, Bufton, J.C, Kupinska, K, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. | 登録日 | 2019-06-18 | 公開日 | 2019-10-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Design of 3,5-diaryl-2-aminopyridines as receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors To be published
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5UE8
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8SUX
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7BNR
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7BNK
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8EE4
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![BU of 8ee4 by Molmil](/molmil-images/mine/8ee4) | Structure of PtuA | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, PtuA | 著者 | Shen, Z.F, Fu, T.M. | 登録日 | 2022-09-06 | 公開日 | 2024-01-03 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | PtuA and PtuB assemble into an inflammasome-like oligomer for anti-phage defense. Nat.Struct.Mol.Biol., 31, 2024
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7QT2
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![BU of 7qt2 by Molmil](/molmil-images/mine/7qt2) | Antibody FenAb208 - fentanyl complex | 分子名称: | Antibody heavy chain, Antibody light chain, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide | 著者 | Zeelen, J.P, Straaten van, M, Stebbins, C.E. | 登録日 | 2022-01-14 | 公開日 | 2023-05-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl. Cell Rep, 42, 2023
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7QT0
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![BU of 7qt0 by Molmil](/molmil-images/mine/7qt0) | Antibody FenAb136 - fentanyl complex | 分子名称: | 2-[2-[2-[2-[[5-oxidanylidene-5-[2-[4-[phenyl(propanoyl)amino]piperidin-1-yl]ethylamino]pentanoyl]amino]ethanoylamino]ethanoylamino]ethanoylamino]ethanoic acid, Antibody heavy chain, Antibody light chain | 著者 | Zeelen, J.P, Straaten van, M, Stebbins, C.E. | 登録日 | 2022-01-14 | 公開日 | 2023-05-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl. Cell Rep, 42, 2023
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7QT4
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![BU of 7qt4 by Molmil](/molmil-images/mine/7qt4) | Antibody FenAb709 - fentanyl complex | 分子名称: | 2-[2-[2-[2-[[5-oxidanylidene-5-[2-[4-[phenyl(propanoyl)amino]piperidin-1-yl]ethylamino]pentanoyl]amino]ethanoylamino]ethanoylamino]ethanoylamino]ethanoic acid, Antibody heavy chain, Antibody light chain | 著者 | Zeelen, J.P, Straaten van, M, Stebbins, C.E. | 登録日 | 2022-01-14 | 公開日 | 2023-05-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl. Cell Rep, 42, 2023
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7QT3
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![BU of 7qt3 by Molmil](/molmil-images/mine/7qt3) | Antibody FenAb609 - fentanyl complex | 分子名称: | Antibody heavy chain, Antibody light chain, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide | 著者 | Zeelen, J.P, Straaten van, M, Stebbins, C.E. | 登録日 | 2022-01-14 | 公開日 | 2023-05-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl. Cell Rep, 42, 2023
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5E1E
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4YGX
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8GYD
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![BU of 8gyd by Molmil](/molmil-images/mine/8gyd) | Structure of Schistosoma japonicum Glutathione S-transferase bound with the ligand complex of 16 | 分子名称: | (2R)-2-[[2-(5-chloranylthiophen-2-yl)-4-oxidanylidene-6-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]quinazolin-3-yl]methyl]-3-(4-chlorophenyl)propanoic acid, ETHANOL, Glutathione S-transferase class-mu 26 kDa isozyme | 著者 | Wen, X, Jin, R, Hu, H, Zhu, J, Song, W, Lu, X. | 登録日 | 2022-09-22 | 公開日 | 2023-08-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1 H )-one Focused DNA-Encoded Library. J.Med.Chem., 66, 2023
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