6M7Z
 
 | | A divergent kinase lacking the glycine-rich loop regulates membrane ultrastructure of the Toxoplasma parasitophorous vacuole | | 分子名称: | 1,2-ETHANEDIOL, Bradyzoite pseudokinase 1, CHLORIDE ION | | 著者 | Beraki, T, Borek, D.M, Reese, M.L. | | 登録日 | 2018-08-21 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Divergent kinase regulates membrane ultrastructure of theToxoplasmaparasitophorous vacuole.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6VOS
 | | Crystal structure of macaque anti-HIV-1 antibody RM20J | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, HEXAETHYLENE GLYCOL, NONAETHYLENE GLYCOL, ... | | 著者 | Yuan, M, Wilson, I.A. | | 登録日 | 2020-01-31 | | 公開日 | 2020-09-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | | 主引用文献 | Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
Plos Pathog., 16, 2020
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6VSR
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6VOR
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7PYK
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in more-swiveled conformation) | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | | 登録日 | 2021-10-10 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7Q0J
 | | RNA polymerase elongation complex in more-swiveled conformation | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | | 登録日 | 2021-10-15 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7PY7
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG elongation complex in more-swiveled conformation) | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | | 登録日 | 2021-10-09 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7PY0
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (NusG-EC in more-swiveled conformation) | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | | 登録日 | 2021-10-08 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7PY8
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (NusG-EC in less-swiveled conformation) | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | | 登録日 | 2021-10-09 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7PY5
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (the consensus NusA-NusG-EC) | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | | 登録日 | 2021-10-09 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7PY3
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (the consensus NusA-EC) | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | | 登録日 | 2021-10-08 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7PY6
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA and NusG (NusA and NusG elongation complex in less-swiveled conformation) | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | | 登録日 | 2021-10-09 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7Q0K
 | | RNA polymerase elongation complex in less-swiveled conformation | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | | 登録日 | 2021-10-15 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7PY1
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (the consensus NusG-EC) | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | | 登録日 | 2021-10-08 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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7PYJ
 | | CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (NusA elongation complex in less-swiveled conformation) | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhu, C, Guo, X, Weixlbaumer, A. | | 登録日 | 2021-10-10 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
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6CAH
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6CCD
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4XLL
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6ZTN
 | | E. coli 70S-RNAP expressome complex in NusG-coupled state (42 nt intervening mRNA) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Webster, M.W, Takacs, M, Weixlbaumer, A. | | 登録日 | 2020-07-20 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
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6ZTM
 | | E. coli 70S-RNAP expressome complex in collided state without NusG | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Webster, M.W, Takacs, M, Weixlbaumer, A. | | 登録日 | 2020-07-20 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
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6Y5M
 | | Crystal structure of mouse Autotaxin in complex with compound 1a | | 分子名称: | (~{E})-3-[4-chloranyl-2-[(5-methyl-1,2,3,4-tetrazol-2-yl)methyl]phenyl]-1-[(2~{R})-4-[(4-fluorophenyl)methyl]-2-methyl-piperazin-1-yl]prop-2-en-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Faller, M, Zink, F. | | 登録日 | 2020-02-25 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.011 Å) | | 主引用文献 | Development of autotaxin inhibitors: A series of tetrazole cinnamides.
Bioorg.Med.Chem.Lett., 31, 2021
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7OEX
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2WYQ
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7LX2
 | | Cryo-EM structure of ConSOSL.UFO.664 (ConS) in complex with bNAb PGT122 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Env glycoprotein gp160, ... | | 著者 | Martin, G.M, Ward, A.B, Sattentau, Q.J. | | 登録日 | 2021-03-03 | | 公開日 | 2022-03-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens.
Npj Vaccines, 8, 2023
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7LX3
 | | Cryo-EM structure of EDC-crosslinked ConSOSL.UFO.664 (ConS-EDC) in complex with bNAb PGT122 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Env glycoprotein gp160, ... | | 著者 | Martin, G.M, Ward, A.B, Sattentau, Q.J. | | 登録日 | 2021-03-03 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens.
Npj Vaccines, 8, 2023
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