2C5D
 
 | | Structure of a minimal Gas6-Axl complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN 6 PRECURSOR, ... | | 著者 | Sasaki, T, Knyazev, P.G, Clout, N.J, Cheburkin, Y, Goehring, W, Ullrich, A, Timpl, R, Hohenester, E. | | 登録日 | 2005-10-26 | | 公開日 | 2005-12-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural Basis for Gas6-Axl Signalling.
Embo J., 25, 2006
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3ION
 | | PDK1 in complex with Compound 8h | | 分子名称: | 2-(5-{[(2S)-2-amino-3-phenylpropyl]oxy}pyridin-3-yl)-8,9-dimethoxybenzo[c][2,7]naphthyridin-4-amine, 3-phosphoinositide-dependent protein kinase 1, SULFATE ION | | 著者 | Olland, A.M. | | 登録日 | 2009-08-14 | | 公開日 | 2010-02-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-ylamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1).
Eur.J.Med.Chem., 45, 2010
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4DAY
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1Q53
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3U6J
 | | Crystal structure of the VEGFR2 kinase domain in complex with a pyrazolone inhibitor | | 分子名称: | N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide, Vascular endothelial growth factor receptor 2 | | 著者 | Whittington, D.A, Long, A, Rose, P, Gu, Y, Zhao, H. | | 登録日 | 2011-10-12 | | 公開日 | 2012-02-22 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structure-based design of novel class II c-Met inhibitors: 1. Identification of pyrazolone-based derivatives.
J.Med.Chem., 55, 2012
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7XK8
 | | Cryo-EM structure of the Neuromedin U receptor 2 (NMUR2) in complex with G Protein and its endogeneous Peptide-Agonist NMU25 | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Zhao, W, Wenru, Z, Mu, W, Minmin, L, Shutian, C, Tingting, T, Gisela, S, Holger, W, Albert, B, Cuiying, Y, Xiaojing, C, Han, S, Wu, B, Zhao, Q. | | 登録日 | 2022-04-19 | | 公開日 | 2023-02-22 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Ligand recognition and activation of neuromedin U receptor 2.
Nat Commun, 13, 2022
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1O0F
 | | RNASE A in complex with 3',5'-ADP | | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, Ribonuclease pancreatic | | 著者 | Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M. | | 登録日 | 2003-02-21 | | 公開日 | 2003-12-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors
PROTEIN SCI., 12, 2003
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1ARJ
 | | ARG-BOUND TAR RNA, NMR | | 分子名称: | ARGININE, TAR RNA | | 著者 | Aboul-Ela, F, Varani, G, Karn, J. | | 登録日 | 1995-08-30 | | 公開日 | 1996-11-08 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of the human immunodeficiency virus type-1 TAR RNA reveals principles of RNA recognition by Tat protein.
J.Mol.Biol., 253, 1995
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1O0M
 | | Ribonuclease A in complex with uridine-2'-phosphate | | 分子名称: | PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER, Ribonuclease pancreatic | | 著者 | Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M. | | 登録日 | 2003-02-24 | | 公開日 | 2003-12-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors
PROTEIN SCI., 12, 2003
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1O66
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1O60
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1O0N
 | | Ribonuclease A in complex with uridine-3'-phosphate | | 分子名称: | 3'-URIDINEMONOPHOSPHATE, Ribonuclease pancreatic | | 著者 | Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M. | | 登録日 | 2003-02-24 | | 公開日 | 2003-12-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors
PROTEIN SCI., 12, 2003
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1O65
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1X6M
 | | Crystal structure of the glutathione-dependent formaldehyde-activating enzyme (Gfa) | | 分子名称: | GLYCEROL, Glutathione-dependent formaldehyde-activating enzyme, SULFATE ION, ... | | 著者 | Neculai, A.M, Neculai, D, Vorholt, J.A, Becker, S. | | 登録日 | 2004-08-11 | | 公開日 | 2004-11-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A dynamic zinc redox switch
J.Biol.Chem., 280, 2005
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1O67
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1O61
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1O64
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1O62
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2W17
 | | CDK2 in complex with the imidazole pyrimidine amide, compound (S)-8b | | 分子名称: | ACETATE ION, CELL DIVISION PROTEIN KINASE 2, N-(4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-amine | | 著者 | Jones, C.D, Andrews, D.M, Barker, A.J, Blades, K, Daunt, P, East, S, Geh, C, Graham, M.A, Johnson, K.M, Loddick, S.A, McFarland, H.M, McGregor, A, Moss, L, Rudge, D.A, Simpson, P.B, Swain, M.L, Tam, K.Y, Tucker, J.A, Walker, M, Brassington, C, Haye, H, McCall, E. | | 登録日 | 2008-10-15 | | 公開日 | 2008-11-04 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The Discovery of Azd5597, a Potent Imidazole Pyrimidine Amide Cdk Inhibitor Suitable for Intravenous Dosing.
Bioorg.Med.Chem.Lett., 18, 2008
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2KUZ
 | | 2-Aminopurine incorporation perturbs the dynamics and structure of DNA | | 分子名称: | DNA (5'-D(*CP*GP*AP*CP*GP*TP*TP*TP*GP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*CP*AP*AP*AP*CP*GP*TP*CP*G)-3') | | 著者 | Dallmann, A, Dehmel, L, Peters, T, Muegge, C, Griesinger, C.P, Tuma, J, Ernsting, N.P. | | 登録日 | 2010-03-03 | | 公開日 | 2010-07-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | 2-aminopurine incorporation perturbs the dynamics and structure of DNA.
Angew.Chem.Int.Ed.Engl., 49, 2010
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1O6D
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1AQK
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1O69
 | | Crystal structure of a PLP-dependent enzyme | | 分子名称: | (2-AMINO-4-FORMYL-5-HYDROXY-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, BETA-MERCAPTOETHANOL, aminotransferase | | 著者 | Structural GenomiX | | 登録日 | 2003-10-23 | | 公開日 | 2003-11-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structural analysis of a set of proteins resulting from a bacterial genomics project
Proteins, 60, 2005
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3LSA
 | | Padron0.9-OFF (non-fluorescent state) | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ... | | 著者 | Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S. | | 登録日 | 2010-02-12 | | 公開日 | 2010-03-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron.
J.Biol.Chem., 285, 2010
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1O68
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