4JRV
| Crystal structure of EGFR kinase domain in complex with compound 4c | 分子名称: | 4-(dimethylamino)-N-[3-(4-{[(1S)-2-hydroxy-1-phenylethyl]amino}-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl]butanamide, Epidermal growth factor receptor | 著者 | Peng, Y.H, Wu, J.S. | 登録日 | 2013-03-22 | 公開日 | 2013-06-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Protein Kinase Inhibitor Design by Targeting the Asp-Phe-Gly (DFG) Motif: The Role of the DFG Motif in the Design of Epidermal Growth Factor Receptor Inhibitors J.Med.Chem., 56, 2013
|
|
6DEJ
| |
3H59
| Hepatitis C virus polymerase NS5B with thiazine inhibitor 2 | 分子名称: | N-{3-[(5S)-5-(1,1-dimethylpropyl)-1-(4-fluoro-3-methylbenzyl)-4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]-1,1-dioxido-4H-1,4-benzothiazin-7-yl}methanesulfonamide, RNA-directed RNA polymerase | 著者 | Harris, S.F, Ghate, M. | 登録日 | 2009-04-21 | 公開日 | 2009-09-08 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Non-nucleoside inhibitors of HCV polymerase NS5B. Part 3: synthesis and optimization studies of benzothiazine-substituted tetramic acids Bioorg.Med.Chem.Lett., 19, 2009
|
|
4HYS
| |
4HYU
| |
2D2R
| Crystal structure of Helicobacter pylori Undecaprenyl Pyrophosphate Synthase | 分子名称: | Undecaprenyl Pyrophosphate Synthase | 著者 | Kuo, C.J, Guo, R.T, Chen, C.L, Ko, T.P, Cheng, Y.S, Cheng, Y.L, Liang, P.H, Wang, A.H.-J. | 登録日 | 2005-09-16 | 公開日 | 2006-09-26 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases. J.Biomed.Biotechnol., 2008, 2008
|
|
2DTN
| Crystal structure of Helicobacter pylori undecaprenyl pyrophosphate synthase complexed with pyrophosphate | 分子名称: | DIPHOSPHATE, undecaprenyl pyrophosphate synthase | 著者 | Guo, R.T, Kuo, C.J, Chen, C.L, Ko, T.P, Liang, P.H, Wang, A.H.-J. | 登録日 | 2006-07-13 | 公開日 | 2007-06-26 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Biochemical characterization, crystal structure, and inhibitors of Helicobacter pylori undecaprenyl pyrophosphate synthase To be Published
|
|