7QAN
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![BU of 7qan by Molmil](/molmil-images/mine/7qan) | Cytochrome P450 Enzyme AbyV | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, Cytochrome P450, ... | 著者 | Parnell, A.E, Back, C.R, Race, P.R. | 登録日 | 2021-11-17 | 公開日 | 2022-11-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis. Angew.Chem.Int.Ed.Engl., 62, 2023
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2KGD
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![BU of 2kgd by Molmil](/molmil-images/mine/2kgd) | NMR Solution Structures of 3-oxo-butyl-ACP, an intermediate mimic from the actinorhodin polyketide synthase in Streptomyces coelicolor | 分子名称: | Actinorhodin polyketide synthase acyl carrier protein, N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-{2-[(3-oxobutyl)sulfanyl]ethyl}-beta-alaninamide | 著者 | Crump, M.P, Evans, S.E, Williams, C. | 登録日 | 2009-03-08 | 公開日 | 2009-04-14 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). J.Mol.Biol., 389, 2009
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2KGC
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![BU of 2kgc by Molmil](/molmil-images/mine/2kgc) | |
2KG9
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![BU of 2kg9 by Molmil](/molmil-images/mine/2kg9) | NMR Solution Structures of butyryl-ACP (a non-polar, non pathway intermediate) from the actinorhodin polyketide synthase in Streptomyces coelicolor | 分子名称: | Actinorhodin polyketide synthase acyl carrier protein, THIOBUTYRIC ACID S-{2-[3-(2-HYDROXY-3,3-DIMETHYL-4-PHOSPHONOOXY-BUTYRYLAMINO)-PROPIONYLAMINO]-ETHYL} ESTER | 著者 | Crump, M.P, Evans, S.E, Williams, C. | 登録日 | 2009-03-07 | 公開日 | 2009-04-14 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). J.Mol.Biol., 389, 2009
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2KGE
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![BU of 2kge by Molmil](/molmil-images/mine/2kge) | NMR Solution Structures of 3,5-dioxohexyl ACP (a triketide mimic) from the actinorhodin polyketide synthase in Streptomyces coelicolor | 分子名称: | Actinorhodin polyketide synthase acyl carrier protein, N-{2-[(3,5-dioxohexyl)sulfanyl]ethyl}-N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide | 著者 | Crump, M.P, Evans, S.E, Williams, C. | 登録日 | 2009-03-08 | 公開日 | 2009-04-14 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). J.Mol.Biol., 389, 2009
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2KG8
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![BU of 2kg8 by Molmil](/molmil-images/mine/2kg8) | NMR Solution Structures of malonyl ACP from the actinorhodin polyketide synthase in Streptomyces coelicolor | 分子名称: | 3-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-3-oxopropanoic acid, Actinorhodin polyketide synthase acyl carrier protein | 著者 | Crump, M.P, Evans, S.E, Williams, C, Eliza, P. | 登録日 | 2009-03-06 | 公開日 | 2009-04-14 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). J.Mol.Biol., 389, 2009
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2KGA
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2L22
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![BU of 2l22 by Molmil](/molmil-images/mine/2l22) | |
4YWF
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![BU of 4ywf by Molmil](/molmil-images/mine/4ywf) | AbyA5 | 分子名称: | AbyA5 | 著者 | Byrne, M.J, Race, P.R. | 登録日 | 2015-03-20 | 公開日 | 2016-06-29 | 最終更新日 | 2019-06-19 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | An Esterase-like Lyase Catalyzes Acetate Elimination in Spirotetronate/Spirotetramate Biosynthesis. Angew.Chem.Int.Ed.Engl., 58, 2019
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2KOO
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![BU of 2koo by Molmil](/molmil-images/mine/2koo) | |
2KOP
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2KG6
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![BU of 2kg6 by Molmil](/molmil-images/mine/2kg6) | Solution Structure of the acetyl Actinorhodin Acyl Carrier Protein from Streptomyces coelicolor | 分子名称: | Actinorhodin polyketide synthase acyl carrier protein, THIOACETIC ACID S-{2-[3-(2-HYDROXY-3,3-DIMETHYL-4-PHOSPHONOOXY-BUTYRYLAMINO)-PROPIONYLAMINO]-ETHYL} ESTER | 著者 | Crump, M.P, Evans, S.E, Eliza, P, Christopher, W. | 登録日 | 2009-03-06 | 公開日 | 2009-04-14 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Probing the Interactions of Early Polyketide Intermediates with the Actinorhodin ACP from S. coelicolor A3(2). J.Mol.Biol., 389, 2009
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2KOS
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2KOR
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2KOQ
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![BU of 2koq by Molmil](/molmil-images/mine/2koq) | NMR solution structures of 3-hydroxyoctanoyl-ACP from Streptomyces coelicolor Fatty Acid Synthase | 分子名称: | Acyl carrier protein, S-[2-[3-[[(2S)-2-hydroxy-3,3-dimethyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3R)-3-hydroxyoctanethioate | 著者 | Ploskon, E, Arthur, C.J, Kanari, A.J, Crump, M.P. | 登録日 | 2009-09-29 | 公開日 | 2010-08-18 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Recognition of intermediate functionality by acyl carrier protein over a complete cycle of fatty acid biosynthesis Chem.Biol., 17, 2010
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5DYQ
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![BU of 5dyq by Molmil](/molmil-images/mine/5dyq) | AbyU L73M L139M | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, YD repeat-containing protein | 著者 | Byrne, M.J, Race, P.R. | 登録日 | 2015-09-25 | 公開日 | 2016-06-08 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | The Catalytic Mechanism of a Natural Diels-Alderase Revealed in Molecular Detail. J.Am.Chem.Soc., 138, 2016
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5DYV
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![BU of 5dyv by Molmil](/molmil-images/mine/5dyv) | AbyU - wildtype | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, YD repeat-containing protein | 著者 | Race, P.R, Byrne, M.J. | 登録日 | 2015-09-25 | 公開日 | 2016-06-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Catalytic Mechanism of a Natural Diels-Alderase Revealed in Molecular Detail. J.Am.Chem.Soc., 138, 2016
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6TBB
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6TBC
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![BU of 6tbc by Molmil](/molmil-images/mine/6tbc) | Crystal structure of S. aureus FabI in complex with NADPH and kalimantacin B | 分子名称: | (2~{E},5~{R},10~{E},12~{E},15~{S},19~{R})-20-[[(2~{R},3~{R})-3-aminocarbonyloxy-2-methyl-butanoyl]amino]-3,5,15-trimethyl-7-methylidene-19-oxidanyl-17-oxidanylidene-icosa-2,10,12-trienoic acid, Enoyl-[acyl-carrier-protein] reductase [NADPH], NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Fage, C.D, Masschelein, J. | 登録日 | 2019-11-01 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl-Acyl Carrier Protein Binding Site of FabI. Angew.Chem.Int.Ed.Engl., 59, 2020
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4Q1H
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![BU of 4q1h by Molmil](/molmil-images/mine/4q1h) | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-branching | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Polyketide biosynthesis enoyl-CoA isomerase PksI, ... | 著者 | Nair, A.V, Race, P.R, Till, M. | 登録日 | 2014-04-03 | 公開日 | 2015-05-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-methyl branch incorporation. Sci Rep, 10, 2020
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4Q1K
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4Q1J
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![BU of 4q1j by Molmil](/molmil-images/mine/4q1j) | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-branching | 分子名称: | 1,2-ETHANEDIOL, Polyketide biosynthesis enoyl-CoA isomerase PksI, SODIUM ION | 著者 | Nair, A.V, Race, P.R, Till, M. | 登録日 | 2014-04-03 | 公開日 | 2015-05-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-methyl branch incorporation. Sci Rep, 10, 2020
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4Q1I
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4Q1G
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![BU of 4q1g by Molmil](/molmil-images/mine/4q1g) | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-branching | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Polyketide biosynthesis enoyl-CoA isomerase PksI | 著者 | Nair, A.V, Race, P.R, Till, M. | 登録日 | 2014-04-03 | 公開日 | 2015-05-06 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and mechanism of a dehydratase/decarboxylase enzyme couple involved in polyketide beta-methyl branch incorporation. Sci Rep, 10, 2020
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