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6AOY
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BU of 6aoy by Molmil
F9 pilus adhesin FmlH lectin domain from E. coli UTI89 co-crystallized with o-nitrophenyl beta-galactoside (ONPG)
分子名称: 2-nitrophenyl beta-D-galactopyranoside, Fml fimbrial adhesin FmlD, SULFATE ION
著者Kalas, V, Hultgren, S.J.
登録日2017-08-16
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Proc.Natl.Acad.Sci.USA, 115, 2018
1J8R
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BU of 1j8r by Molmil
BINARY COMPLEX OF THE PAPG RECEPTOR-BINDING DOMAIN BOUND TO GBO4 RECEPTOR
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, PYELONEPHRITIC ADHESIN
著者Dodson, K.W, Pinkner, J.S, Rose, T, Magnusson, G, Hultgren, S.J, Waksman, G, Midwest Center for Structural Genomics (MCSG)
登録日2001-05-22
公開日2001-06-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of the interaction of the pyelonephritic E. coli adhesin to its human kidney receptor.
Cell(Cambridge,Mass.), 105, 2001
6CD2
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BU of 6cd2 by Molmil
Crystal structure of the PapC usher bound to the chaperone-adhesin PapD-PapG
分子名称: Chaperone protein PapD, Outer membrane usher protein PapC, PapGII adhesin protein
著者Omattage, N.S, Deng, Z, Yuan, P, Hultgren, S.J.
登録日2018-02-07
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in Escherichia coli.
Nat Microbiol, 3, 2018
3L48
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BU of 3l48 by Molmil
Crystal structure of the C-terminal domain of the PapC usher
分子名称: COBALT (II) ION, Outer membrane usher protein PapC
著者Ford, B.A, Hultgren, S.J.
登録日2009-12-18
公開日2010-03-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Homology between the C-Terminal Domain of the PapC Usher and Its Plug.
J.Bacteriol., 192, 2010
1UWF
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BU of 1uwf by Molmil
1.7 A resolution structure of the receptor binding domain of the FimH adhesin from uropathogenic E. coli
分子名称: FIMH PROTEIN, GLYCEROL, butyl alpha-D-mannopyranoside
著者Bouckaert, J, Berglund, J, Genst, E.D, Cools, L, Hung, C.-S, Wuhrer, M, Zavialov, A, Langermann, S, Hultgren, S, Wyns, L, Oscarson, S, Knight, S.D, De Greve, H.
登録日2004-02-05
公開日2005-02-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Receptor Binding Studies Disclose a Novel Class of High-Affinity Inhibitors of the Escherichia Coli Fimh Adhesin.
Mol.Microbiol., 55, 2005
5NWP
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BU of 5nwp by Molmil
Crystal Structure of the Lectin Domain From the F17-like Adhesin, UclD
分子名称: Adhesin, SULFATE ION
著者Ruer, S, Remaut, H.
登録日2017-05-08
公開日2017-06-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.
Nature, 546, 2017
4J3O
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BU of 4j3o by Molmil
Crystal structure of the FimD usher traversed by the pilus tip complex assembly composed of FimC:FimF:FimG:FimH
分子名称: Chaperone protein FimC, Outer membrane usher protein FimD, Protein FimF, ...
著者Geibel, S, Waksman, G.
登録日2013-02-06
公開日2013-04-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural and energetic basis of folded-protein transport by the FimD usher.
Nature, 496, 2013
2NA4
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BU of 2na4 by Molmil
Curli secretion specificity factor CsgE W48A/F79A mutant
分子名称: Curli production assembly/transport component CsgE
著者Shu, Q, Krezel, A.M, Frieden, C.
登録日2015-12-21
公開日2016-06-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution NMR structure of CsgE: Structural insights into a chaperone and regulator protein important for functional amyloid formation.
Proc.Natl.Acad.Sci.USA, 113, 2016
3OHN
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BU of 3ohn by Molmil
Crystal structure of the FimD translocation domain
分子名称: Outer membrane usher protein FimD
著者Wang, T, Li, H.
登録日2010-08-17
公開日2011-06-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.011 Å)
主引用文献Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate.
Nature, 474, 2011
3RFZ
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BU of 3rfz by Molmil
Crystal structure of the FimD usher bound to its cognate FimC:FimH substrate
分子名称: Chaperone protein fimC, Outer membrane usher protein, type 1 fimbrial synthesis, ...
著者Phan, G, Remaut, H, Lebedev, A, Geibel, S, Waksman, G.
登録日2011-04-07
公開日2011-06-01
最終更新日2012-03-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate.
Nature, 474, 2011
3QB2
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BU of 3qb2 by Molmil
The Crystal Structure of Immunity Factor for SPN (IFS)
分子名称: Immunity factor for SPN, SULFATE ION
著者Smith, C.L, Ellenberger, T.
登録日2011-01-12
公開日2011-03-16
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis of Streptococcus pyogenes Immunity to Its NAD(+) Glycohydrolase Toxin.
Structure, 19, 2011
6C53
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BU of 6c53 by Molmil
Cryo-EM structure of the Type 1 pilus rod
分子名称: Type-1 fimbrial protein, A chain
著者Zheng, W, Wang, F, Luna-Rico, A, Francetic, O, Hultgren, S.J, Egelman, E.H.
登録日2018-01-13
公開日2018-01-31
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions.
Elife, 7, 2018
7Q3N
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BU of 7q3n by Molmil
Cryo-EM of the complex between human uromodulin (UMOD)/Tamm-Horsfall protein (THP) and the FimH lectin domain from uropathogenic E. coli
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Type 1 fimbiral adhesin FimH, ...
著者Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B.
登録日2021-10-28
公開日2022-03-16
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
1KLF
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BU of 1klf by Molmil
FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE
分子名称: CHAPERONE PROTEIN FIMC, FIMH PROTEIN, alpha-D-mannopyranose
著者Hung, C.S, Bouckaert, J.
登録日2001-12-11
公開日2002-06-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection.
Mol.Microbiol., 44, 2002
1KIU
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BU of 1kiu by Molmil
FimH adhesin Q133N mutant-FimC chaperone complex with methyl-alpha-D-mannose
分子名称: CHAPERONE PROTEIN FimC, FimH PROTEIN, methyl alpha-D-mannopyranoside
著者Hung, C.S, Bouckaert, J.
登録日2001-12-03
公開日2002-06-05
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection.
Mol.Microbiol., 44, 2002
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