4QED
| ElxO Y152F with NADPH Bound | 分子名称: | ElxO, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION | 著者 | Garg, N, Nair, S.K. | 登録日 | 2014-05-15 | 公開日 | 2014-07-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Substrate Specificity of the Lanthipeptide Peptidase ElxP and the Oxidoreductase ElxO. Acs Chem.Biol., 9, 2014
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4RNM
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6M03
| The crystal structure of COVID-19 main protease in apo form | 分子名称: | 3C-like proteinase | 著者 | Zhang, B, Zhao, Y, Jin, Z, Liu, X, Yang, H, Rao, Z. | 登録日 | 2020-02-19 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 119, 2022
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8UVK
| CosR DNA bound form II | 分子名称: | DI(HYDROXYETHYL)ETHER, DNA (5'-D(*AP*AP*TP*TP*AP*AP*GP*AP*TP*AP*TP*TP*AP*TP*TP*AP*AP*CP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*GP*TP*TP*AP*AP*TP*AP*AP*TP*AP*TP*CP*TP*TP*AP*AP*TP*T)-3'), ... | 著者 | Zhang, Z. | 登録日 | 2023-11-03 | 公開日 | 2024-01-31 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structural basis of DNA recognition of the Campylobacter jejuni CosR regulator. Mbio, 15, 2024
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8UUZ
| Campylobacter jejuni CosR apo form | 分子名称: | DNA-binding response regulator | 著者 | Zhang, Z. | 登録日 | 2023-11-02 | 公開日 | 2024-01-31 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | 主引用文献 | Structural basis of DNA recognition of the Campylobacter jejuni CosR regulator. Mbio, 15, 2024
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8UVX
| CosR DNA bound form I | 分子名称: | DNA (5'-D(*AP*TP*AP*TP*CP*TP*TP*AP*AP*TP*TP*TP*TP*GP*GP*TP*TP*AP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*TP*AP*AP*CP*CP*AP*AP*AP*AP*TP*TP*AP*AP*GP*AP*TP*AP*T)-3'), DNA-binding response regulator | 著者 | Zhang, Z. | 登録日 | 2023-11-05 | 公開日 | 2024-01-31 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis of DNA recognition of the Campylobacter jejuni CosR regulator. Mbio, 15, 2024
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5HDX
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5HE4
| BACE-1 in complex with (4aR,7aS)-7a-(2,6-difluorophenyl)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-3-methyl-4-oxooctahydro-2H-pyrrolo[3,4-d]pyrimidin-2-iminium | 分子名称: | (2E,4aR,7aS)-7a-(2,6-difluorophenyl)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-2-imino-3-methyloctahydro-4H-pyrrolo[3,4-d]pyrimidin-4-one, Beta-secretase 1, L(+)-TARTARIC ACID | 著者 | Orth, P. | 登録日 | 2016-01-05 | 公開日 | 2016-03-16 | 最終更新日 | 2016-04-27 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Structure-Based Design of an Iminoheterocyclic beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central A beta in Nonhuman Primates. J.Med.Chem., 59, 2016
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5HDZ
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5HE7
| BACE-1 in complex with (4aR,7aS)-7a-(2,4-difluorophenyl)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-2-imino-3-methyloctahydro-4H-pyrrolo[3,4-d]pyrimidin-4-one | 分子名称: | (2E,4aR,7aS)-7a-(2,4-difluorophenyl)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-2-imino-3-methyloctahydro-4H-pyrrolo[3,4-d]pyrimidin-4-one, Beta-secretase 1 | 著者 | Orth, P. | 登録日 | 2016-01-05 | 公開日 | 2016-03-16 | 最終更新日 | 2016-04-27 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Structure-Based Design of an Iminoheterocyclic beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central A beta in Nonhuman Primates. J.Med.Chem., 59, 2016
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5HD0
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5HDU
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5HDV
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7Y4H
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2MJV
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8DL9
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8DLB
| Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound Z2799209083 | 分子名称: | 1-[(5S)-5-(3,4-dimethoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one, 3C-like proteinase | 著者 | Kovalevsky, A.Y, Coates, L, Kneller, D.W. | 登録日 | 2022-07-07 | 公開日 | 2023-05-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2. J.Chem.Inf.Model., 63, 2023
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4DUR
| The X-ray Crystal Structure of Full-Length type II Human Plasminogen | 分子名称: | ACETATE ION, BICARBONATE ION, CHLORIDE ION, ... | 著者 | Law, R.H.P, Caradoc-Davies, T, Whisstock, J.C. | 登録日 | 2012-02-22 | 公開日 | 2012-03-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | The X-ray crystal structure of full-length human plasminogen Cell Rep, 1, 2012
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4DUU
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4CGR
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5ER7
| Connexin-26 Bound to Calcium | 分子名称: | CALCIUM ION, Gap junction beta-2 protein | 著者 | Purdy, M.D, Bennett, B.C, Baker, K.A, Yeager, M.J. | 登録日 | 2015-11-13 | 公開日 | 2016-01-27 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (3.286 Å) | 主引用文献 | An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels. Nat Commun, 7, 2016
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8JSC
| Structure of the FSP1 protein from Human | 分子名称: | 6-HYDROXY-FLAVIN-ADENINE DINUCLEOTIDE, Ferroptosis suppressor protein 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Zhang, S.T, Jia, D. | 登録日 | 2023-06-19 | 公開日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | FSP1 oxidizes NADPH to suppress ferroptosis. Cell Res., 33, 2023
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5ERA
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7BYF
| The crystal structure of mouse ORF10-Rae1-Nup98 complex | 分子名称: | 10 protein, MERCURY (II) ION, Peptidase S59 domain-containing protein, ... | 著者 | Gao, P, Feng, H. | 登録日 | 2020-04-22 | 公開日 | 2021-03-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10. Proc.Natl.Acad.Sci.USA, 117, 2020
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8K31
| The complex of WRKY33 C terminal DBD and SIB1 | 分子名称: | Probable WRKY transcription factor 33, Sigma factor binding protein 1, chloroplastic, ... | 著者 | Dong, X, Gong, Z, Hu, Y.F. | 登録日 | 2023-07-14 | 公開日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for the regulation of plant transcription factor WRKY33 by the VQ protein SIB1. Commun Biol, 7, 2024
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