9E6T
 
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9C12
 | | Leukotriene C4-bound Multidrug Resistance-associated Protein 2 (MRP2) | | 分子名称: | (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-3-( 2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid, ATP-binding cassette sub-family C member 2, CHOLESTEROL, ... | | 著者 | Koide, E, Chen, J. | | 登録日 | 2024-05-28 | | 公開日 | 2024-12-18 | | 最終更新日 | 2025-02-12 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Structural basis for the transport and regulation mechanism of the multidrug resistance-associated protein 2.
Nat Commun, 16, 2025
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9D7I
 | | Cryo-EM structure of BG505 DS-SOSIP.664 with 2 CH103 KN Fabs bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH103 Fab light chain, ... | | 著者 | Parsons, R.J, Acharya, P. | | 登録日 | 2024-08-16 | | 公開日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Acquisition of quaternary trimer interaction as a key step in the lineage maturation of a broad and potent HIV-1 neutralizing antibody.
Structure, 2025
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9D7H
 | | Cryo-EM structure of BG505 DS-SOSIP.664 with 1 CH103 KN Fab bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH103 Fab light chain, ... | | 著者 | Parsons, R.J, Acharya, P. | | 登録日 | 2024-08-16 | | 公開日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | Acquisition of quaternary trimer interaction as a key step in the lineage maturation of a broad and potent HIV-1 neutralizing antibody.
Structure, 2025
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9D7G
 | | BG505 DS-SOSIP.664 apo structure from the CH103 KN cryo-EM dataset | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Surface protein gp120, ... | | 著者 | Parsons, R.J, Acharya, P. | | 登録日 | 2024-08-16 | | 公開日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Acquisition of quaternary trimer interaction as a key step in the lineage maturation of a broad and potent HIV-1 neutralizing antibody.
Structure, 2025
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9D7O
 | | Cryo-EM structure of BG505 DS-SOSIP.664 with 1 CH103 Fab bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH103 Fab heavy chain, ... | | 著者 | Parsons, R.J, Acharya, P. | | 登録日 | 2024-08-16 | | 公開日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (3.56 Å) | | 主引用文献 | Acquisition of quaternary trimer interaction as a key step in the lineage maturation of a broad and potent HIV-1 neutralizing antibody.
Structure, 2025
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9D7P
 | | Cryo-EM structure of BG505 DS-SOSIP.664 with 2 CH103 Fabs bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH103 Fab heavy chain, ... | | 著者 | Parsons, R.J, Acharya, P. | | 登録日 | 2024-08-16 | | 公開日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | Acquisition of quaternary trimer interaction as a key step in the lineage maturation of a broad and potent HIV-1 neutralizing antibody.
Structure, 2025
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9C6M
 | | Yasminevirus c12orf29, a 5' to 3' RNA ligase, K73M mutant | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, RNA ligase1 | | 著者 | Hu, Y, Lopez, V.A, Tagliabracci, V.S, Tomchick, D.R. | | 登録日 | 2024-06-07 | | 公開日 | 2024-10-02 | | 最終更新日 | 2025-03-05 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation.
Proc.Natl.Acad.Sci.USA, 121, 2024
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9C6L
 | | Yasminevirus c12orf29, a 5' to 3' RNA ligase | | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, RNA ligase1, ... | | 著者 | Hu, Y, Lopez, V.A, Tagliabracci, V.S, Tomchick, D.R. | | 登録日 | 2024-06-07 | | 公開日 | 2024-10-02 | | 最終更新日 | 2025-03-05 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Biochemical and structural insights into a 5' to 3' RNA ligase reveal a potential role in tRNA ligation.
Proc.Natl.Acad.Sci.USA, 121, 2024
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9F3Y
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9F3X
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9EUU
 | | Structure of recombinant alpha-synuclein fibrils 1B capable of seeding GCIs in vivo | | 分子名称: | Alpha-synuclein | | 著者 | Burger, D, Kashyrina, M, Lewis, A, De Nuccio, F, Mohammed, I, de La Seigliere, H, van den Heuvel, L, Feuillie, C, Verchere, J, Berbon, M, Arotcarena, M, Retailleau, A, Bezard, E, Laferriere, F, Loquet, A, Bousset, L, Baron, T, Lofrumento, D.D, De Giorgi, F, Stahlberg, H, Ichas, F. | | 登録日 | 2024-03-28 | | 公開日 | 2024-06-05 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (1.93 Å) | | 主引用文献 | 1.94 angstrom structure of synthetic alpha-synuclein fibrils seeding MSA neuropathology
Biorxiv, 2024
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9DIK
 | | Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM681 (N-cyclopropyl-1,4-dimethyl-5-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1H-pyrazole-3-carboxamide) | | 分子名称: | 6-[bis(oxidanyl)methyl]-5~{H}-pyrimidine-2,4-dione, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | | 著者 | Deng, X, Tomchick, D, Phillips, M. | | 登録日 | 2024-09-05 | | 公開日 | 2025-01-01 | | 最終更新日 | 2025-01-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-Based Discovery and Development of Highly Potent Dihydroorotate Dehydrogenase Inhibitors for Malaria Chemoprevention.
J.Med.Chem., 68, 2025
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9DIZ
 | | Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM959 (6-cyclopropyl-2,4-dimethyl-3-((6-(trifluoromethyl)pyridin-3-yl)methyl)-2,6-dihydro-7H-pyrazolo[3,4-c]pyridin-7-one) | | 分子名称: | 6-[bis(oxidanyl)methyl]-5~{H}-pyrimidine-2,4-dione, 6-cyclopropyl-2,4-dimethyl-3-{[6-(trifluoromethyl)pyridin-3-yl]methyl}-2,6-dihydro-7H-pyrazolo[3,4-c]pyridin-7-one, Dihydroorotate dehydrogenase (quinone), ... | | 著者 | Deng, X, Tomchick, D, Phillips, M. | | 登録日 | 2024-09-06 | | 公開日 | 2025-01-01 | | 最終更新日 | 2025-01-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure-Based Discovery and Development of Highly Potent Dihydroorotate Dehydrogenase Inhibitors for Malaria Chemoprevention.
J.Med.Chem., 68, 2025
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9CA5
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9CA6
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9F18
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9EQF
 | | Crystal structure of the L-arginine hydroxylase VioC MeHis316, bound to Fe(II), L-arginine, and succinate | | 分子名称: | 1,2-ETHANEDIOL, ARGININE, Alpha-ketoglutarate-dependent L-arginine hydroxylase, ... | | 著者 | Hardy, F.J. | | 登録日 | 2024-03-21 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Probing Ferryl Reactivity in a Nonheme Iron Oxygenase Using an Expanded Genetic Code.
Acs Catalysis, 14, 2024
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9ETK
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9EVD
 | | In situ structure of the peripheral stalk of the mitochondrial ATPsynthase in whole Polytomella cells | | 分子名称: | ASA-10: Polytomella F-ATP synthase associated subunit 10, ASA-9: Polytomella F-ATP synthase associated subunit 9, ATP synthase associated protein ASA1, ... | | 著者 | Dietrich, L, Agip, A.N.A, Kuehlbrandt, W. | | 登録日 | 2024-03-29 | | 公開日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (5.6 Å) | | 主引用文献 | In situ structure and rotary states of mitochondrial ATP synthase in whole Polytomella cells.
Science, 385, 2024
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9F5U
 | | Crystal structure of Heme-Oxygenase from Corynebacterium diphtheriae complexed with Cobalt-porphyrine (HumO-Co(III)) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, CITRIC ACID, ... | | 著者 | Labidi, R.J, Faivre, B, Carpentier, P, Perard, J, Gotico, P, Li, Y, Atta, M, Fontecave, M. | | 登録日 | 2024-04-30 | | 公開日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Light-Activated Artificial CO 2 -Reductase: Structure and Activity.
J.Am.Chem.Soc., 2024
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9F66
 | | Crystal structure of Heme-Oxygenase from Corynebacterium diphtheriae complexed with Cobalt-porphyrine (HumO-Co(III)) flash-cooled under CO2 pressure | | 分子名称: | 1,2-ETHANEDIOL, CARBON DIOXIDE, CHLORIDE ION, ... | | 著者 | Labidi, R.J, Faivre, B, Carpentier, P, Perard, J, Gotico, P, Li, Y, Atta, M, Fontecave, M. | | 登録日 | 2024-04-30 | | 公開日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Light-Activated Artificial CO 2 -Reductase: Structure and Activity.
J.Am.Chem.Soc., 2024
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8RLY
 | | E. coli endonuclease IV complexed with sulfate, catalytic Fe2+ | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Endonuclease 4, ... | | 著者 | Saper, M.A, Paterson, N.G, Kirillov, S, Rouvinski, A. | | 登録日 | 2024-01-04 | | 公開日 | 2024-12-11 | | 最終更新日 | 2025-01-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Octahedral Iron in Catalytic Sites of Endonuclease IV from Staphylococcus aureus and Escherichia coli .
Biochemistry, 64, 2025
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8RNZ
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8RL2
 | | Human pre-60S - State 5 | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Thoms, M, Denk, T, Beckmann, R. | | 登録日 | 2024-01-02 | | 公開日 | 2025-01-15 | | 最終更新日 | 2025-04-30 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Highly conserved ribosome biogenesis pathways between human and yeast revealed by the MDN1-NLE1 interaction and NLE1 containing pre-60S subunits.
Nucleic Acids Res., 53, 2025
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