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3ZV0
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BU of 3zv0 by Molmil
Structure of the SHQ1P-CBF5P complex
分子名称: GLYCEROL, H/ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 4, PROTEIN SHQ1
著者Walbott, H, Machado-Pinilla, R, Liger, D, Blaud, M, Rety, S, Grozdanov, P.N, Godin, K, vanTilbeurgh, H, Varani, G, Meier, U.T, Leulliot, N.
登録日2011-07-22
公開日2011-11-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The H/Aca Rnp Assembly Factor Shq1 Functions as an RNA Mimic.
Genes Dev., 25, 2011
2AQC
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BU of 2aqc by Molmil
NMR Structural analysis of archaeal Nop10
分子名称: Ribosome biogenesis protein Nop10, ZINC ION
著者Hamma, T, Reichow, S.L, Varani, G, Ferre-D'Amare, A.R.
登録日2005-08-17
公開日2005-11-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
Nat.Struct.Mol.Biol., 12, 2005
2AQA
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BU of 2aqa by Molmil
NMR structural analysis of Nop10p from Saccharomyces cerevisiae
分子名称: H/ACA ribonucleoprotein complex subunit 3
著者Hamma, T, Reichow, S.L, Varani, G, Ferre-D'Amare, A.R.
登録日2005-08-17
公開日2005-11-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
Nat.Struct.Mol.Biol., 12, 2005
5J0M
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BU of 5j0m by Molmil
Ground state sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat
分子名称: Apical region (29-mer) of the HIV-1 TAR RNA element, Cyclic peptide mimetic of HIV-1 Tat
著者Borkar, A.N, Bardaro Jr, M.F, Varani, G, Vendruscolo, M.
登録日2016-03-28
公開日2016-06-08
最終更新日2019-10-23
実験手法SOLUTION NMR
主引用文献Structure of a low-population binding intermediate in protein-RNA recognition.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J1O
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BU of 5j1o by Molmil
Excited state (Bound-like) sampled during RDC restrained Replica-averaged Metadynamics (RAM) simulations of the HIV-1 TAR complexed with cyclic peptide mimetic of Tat
分子名称: Apical region (29mer) of the HIV-1 TAR element, Cyclic peptide mimetic of Tat
著者Borkar, A.N, Bardaro, M.F, Varani, G, Vendruscolo, M.
登録日2016-03-29
公開日2016-06-08
最終更新日2019-10-23
実験手法SOLUTION NMR
主引用文献Structure of a low-population binding intermediate in protein-RNA recognition.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J2W
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BU of 5j2w by Molmil
Intermediate state lying on the pathway of release of Tat from HIV-1 TAR.
分子名称: Apical region (29mer) of the HIV-1 TAR RNA element, Cyclic peptide mimetic of HIV-1 Tat
著者Borkar, A.N, Bardaro Jr, M.F, Varani, G, Vendruscolo, M.
登録日2016-03-30
公開日2016-06-08
最終更新日2019-10-23
実験手法SOLUTION NMR
主引用文献Structure of a low-population binding intermediate in protein-RNA recognition.
Proc.Natl.Acad.Sci.USA, 113, 2016
1QYS
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BU of 1qys by Molmil
Crystal structure of Top7: A computationally designed protein with a novel fold
分子名称: TOP7
著者Kuhlman, B, Dantas, G, Ireton, G.C, Varani, G, Stoddard, B.L, Baker, D.
登録日2003-09-11
公開日2003-11-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
Science, 302, 2003
1Z31
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BU of 1z31 by Molmil
The structure of an enzyme-activating fragment of human telomerase RNA
分子名称: human telomerase PJ6 hairpin
著者Leeper, T.C, Varani, G.
登録日2005-03-10
公開日2005-03-22
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of an enzyme-activating fragment of human telomerase RNA.
RNA, 11, 2005
2A9X
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BU of 2a9x by Molmil
TAR RNA recognition by a cyclic peptidomimetic of Tat protein
分子名称: BIV TAR RNA, BIV-2 cyclic peptide
著者Leeper, T.C, Athanassiou, Z, Dias, R.L, Robinson, J.A, Varani, G.
登録日2005-07-12
公開日2005-11-01
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献TAR RNA recognition by a cyclic peptidomimetic of Tat protein.
Biochemistry, 44, 2005
2APO
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BU of 2apo by Molmil
Crystal Structure of the Methanococcus jannaschii Cbf5 Nop10 Complex
分子名称: POTASSIUM ION, Probable tRNA pseudouridine synthase B, Ribosome biogenesis protein Nop10, ...
著者Hamma, T, Reichow, S.L, Varani, G, Ferre-D'Amare, A.R.
登録日2005-08-16
公開日2005-11-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.
Nat.Struct.Mol.Biol., 12, 2005
1DZ5
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BU of 1dz5 by Molmil
The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein
分子名称: PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3'), U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A
著者Varani, L, Gunderson, S.I, Mattaj, I.W, Kay, L.E, Neuhaus, D, Varani, G.
登録日2000-02-16
公開日2000-03-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein
Nat.Struct.Biol., 7, 2000
1EI2
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BU of 1ei2 by Molmil
STRUCTURAL BASIS FOR RECOGNITION OF THE RNA MAJOR GROOVE IN THE TAU EXON 10 SPLICING REGULATORY ELEMENT BY AMINOGLYCOSIDE ANTIBIOTICS
分子名称: NEOMYCIN, TAU EXON 10 SRE RNA
著者Varani, L, Spillantini, M.G, Goedert, M, Varani, G.
登録日2000-02-23
公開日2000-03-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics.
Nucleic Acids Res., 28, 2000
6DZE
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BU of 6dze by Molmil
Solution structure of Rbfox2 RRM mimetic peptide CPfox7
分子名称: CPfox7
著者Sun, Y.-T, Varani, G.
登録日2018-07-03
公開日2019-05-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b.
Chembiochem, 20, 2019
6DZA
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BU of 6dza by Molmil
Solution structure of Rbfox2 RRM mimetic peptide CPfox4
分子名称: CPfox4
著者Sun, Y.-T, Shortridge, M.D, Varani, G.
登録日2018-07-03
公開日2019-05-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b.
Chembiochem, 20, 2019
6DZB
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BU of 6dzb by Molmil
Solution structure of Rbfox2 RRM mimetic peptide CPfox5
分子名称: CPfox5
著者Sun, Y.-T, Varani, G.
登録日2018-07-03
公開日2019-05-15
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b.
Chembiochem, 20, 2019
1AUD
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BU of 1aud by Molmil
U1A-UTRRNA, NMR, 31 STRUCTURES
分子名称: RNA 3UTR, U1A 102
著者Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G.
登録日1997-08-22
公開日1998-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural basis of the RNA-binding specificity of human U1A protein.
EMBO J., 16, 1997
1IKD
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BU of 1ikd by Molmil
ACCEPTOR STEM, NMR, 30 STRUCTURES
分子名称: TRNA ALA ACCEPTOR STEM
著者Ramos, A, Varani, G.
登録日1996-11-15
公開日1997-04-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the acceptor stem of Escherichia coli tRNA Ala: role of the G3.U70 base pair in synthetase recognition.
Nucleic Acids Res., 25, 1997
1KP7
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BU of 1kp7 by Molmil
Conserved RNA Structure within the HCV IRES eIF3 Binding Site
分子名称: Hepatitis C Virus Internal Ribosome Entry Site Fragment
著者Gallego, J, Klinck, R, Collier, A.J, Cole, P.T, Harris, S.J, Harrison, G.P, Aboul-ela, F, Walker, S, Varani, G.
登録日2001-12-29
公開日2002-04-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A conserved RNA structure within the HCV IRES eIF3-binding site.
Nat.Struct.Biol., 9, 2002
1M5L
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BU of 1m5l by Molmil
Structure of wild-type and mutant internal loops from the SL-1 domain of the HIV-1 packaging signal
分子名称: modified HIV-1 packaging signal stem-loop 1 RNA
著者Gallego, J, Greatorex, J, Varani, G, Lever, A.
登録日2002-07-09
公開日2002-09-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and stability of wild-type and mutant RNA internal loops from the SL-1 domain of the HIV-1 packaging signal
J.Mol.Biol., 322, 2002
5UZT
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BU of 5uzt by Molmil
Structure of wild type pre-miR21 apical loop
分子名称: pre-miR-21
著者Shortridge, M.D, Varani, G.
登録日2017-02-27
公開日2017-05-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing.
ACS Chem. Biol., 12, 2017
5VO7
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BU of 5vo7 by Molmil
NMR Assignment and Structure of Thioredoxin (Rv1471 ortholog) from Mycobacterium smegmatis ATCC 700084 / mc(2)155
分子名称: Thioredoxin
著者Barnwal, R.P, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2017-05-02
公開日2017-06-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Assignment and Structure of Thioredoxin (Rv1471 ortholog) type protein from Mycobacterium smegmatis ATCC 700084 / mc(2)155
To Be Published
5UZZ
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BU of 5uzz by Molmil
Structure of wild type pre-miR21 apical loop
分子名称: 14-mer Peptide, pre-miR21
著者Shortridge, M.D, Varani, G.
登録日2017-02-27
公開日2017-06-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing.
ACS Chem. Biol., 12, 2017
5T3Y
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BU of 5t3y by Molmil
Solution structure of response regulator protein from Burkholderia multivorans
分子名称: Two-component system response regulator
著者Yang, F, Lim, Y.-B, Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2016-08-26
公開日2016-09-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of response regulator protein from Burkholderia multivorans
To Be Published
1P1T
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BU of 1p1t by Molmil
NMR Structure of the N-terminal RRM domain of Cleavage stimulation factor 64 KDa subunit
分子名称: Cleavage stimulation factor, 64 kDa subunit
著者Perez-Canadillas, J.M, Varani, G.
登録日2003-04-14
公開日2003-08-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein
Embo J., 22, 2003
1OQ0
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BU of 1oq0 by Molmil
P6.1 stem loop from the activation domain of hTR
分子名称: P6.1 RNA hairpin from hTR
著者Leeper, T, Leulliot, N, Varani, G.
登録日2003-03-06
公開日2003-05-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of an essential stem-loop of human telomerase RNA
NUCLEIC ACIDS RES., 31, 2003

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