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7GS4
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BU of 7gs4 by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-27
分子名称: 3C-like proteinase nsp5, 7-(hydroxymethyl)-3-methyl-6~{H}-[1,3]thiazolo[3,2-a]pyrimidin-5-one, CHLORIDE ION, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GRO
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BU of 7gro by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-11
分子名称: 3C-like proteinase nsp5, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GRQ
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BU of 7grq by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-13
分子名称: 3C-like proteinase nsp5, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GRM
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BU of 7grm by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-9
分子名称: 3C-like proteinase nsp5, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GRN
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BU of 7grn by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-10
分子名称: 2-[(3S)-pyrrolidin-3-yl]-5-(trifluoromethyl)-1H-benzimidazole, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GRS
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BU of 7grs by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-15
分子名称: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, SODIUM ION, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GRV
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BU of 7grv by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-18
分子名称: (2S)-2-(2-fluorophenyl)-1,3-thiazolidin-4-one, 3C-like proteinase nsp5, CHLORIDE ION, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GS1
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BU of 7gs1 by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-24
分子名称: 2-cyano-~{N}-cyclohexyl-ethanamide, 3C-like proteinase nsp5, CHLORIDE ION, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GS0
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BU of 7gs0 by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-23
分子名称: (pyridin-2-yl)(quinolin-2-yl)methanone, 3C-like proteinase nsp5, CHLORIDE ION, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GRF
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BU of 7grf by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-2
分子名称: 3C-like proteinase nsp5, 5-bromopyridin-3-amine, CHLORIDE ION, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GRJ
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BU of 7grj by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-6
分子名称: (5-chloro-1-benzothiophen-3-yl)methanol, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GRW
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BU of 7grw by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-19
分子名称: (2S)-N-(3,5-dichlorophenyl)-2-hydroxypropanamide, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GRX
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BU of 7grx by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-20
分子名称: 1-(2,4-difluorophenyl)pyrrolidine-2,5-dione, 3C-like proteinase nsp5, CHLORIDE ION, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GRU
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BU of 7gru by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-17
分子名称: 3-(4-chlorophenyl)-1-methyl-1H-pyrazol-5-amine, 3C-like proteinase nsp5, CHLORIDE ION, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.
登録日2023-11-14
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
7GRE
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BU of 7gre by Molmil
Crystal structure of SARS-CoV-2 main protease in complex with cpd-1
分子名称: 3C-like proteinase nsp5, 4-[3-(trifluoromethyl)-1H-pyrazol-5-yl]pyridine, CHLORIDE ION, ...
著者Huang, C.-Y, Metz, A, Sharpe, M, Sweeney, A.M.
登録日2023-11-14
公開日2024-02-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket.
Acta Crystallogr D Struct Biol, 80, 2024
1K4W
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BU of 1k4w by Molmil
X-ray structure of the orphan nuclear receptor ROR beta ligand-binding domain in the active conformation
分子名称: Nuclear receptor ROR-beta, STEARIC ACID, steroid receptor coactivator-1
著者Stehlin, C, Wurtz, J.M, Steinmetz, A, Greiner, E, Schuele, R, Moras, D, Renaud, J.P.
登録日2001-10-09
公開日2002-04-09
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.
EMBO J., 20, 2001
5QZ0
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BU of 5qz0 by Molmil
PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 16
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QZI
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BU of 5qzi by Molmil
PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 33
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QZZ
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BU of 5qzz by Molmil
PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 50
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5R0E
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BU of 5r0e by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry D02, DMSO-free
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, ~{N}-[5-azanyl-2,4-bis(fluoranyl)phenyl]propane-1-sulfonamide
著者Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S.
登録日2020-02-12
公開日2020-06-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QZ7
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BU of 5qz7 by Molmil
PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 22
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QZK
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BU of 5qzk by Molmil
PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 35
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5R00
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BU of 5r00 by Molmil
PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 51
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5R0L
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BU of 5r0l by Molmil
PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment F2X-Entry H11, DMSO-free
分子名称: A1 cistron-splicing factor AAR2, N-cyclopentyl-N'-{[(2R)-oxolan-2-yl]methyl}urea, Pre-mRNA-splicing factor 8
著者Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G, Weiss, M.S.
登録日2020-02-12
公開日2020-06-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020
5QZ6
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BU of 5qz6 by Molmil
PanDDA analysis group deposition -- Auto-refined data of Aar2/RNaseH for ground state model 21
分子名称: A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8
著者Weiss, M.S, Wollenhaupt, J, Metz, A, Barthel, T, Lima, G.M.A, Heine, A, Mueller, U, Klebe, G.
登録日2020-02-12
公開日2020-06-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献F2X-Universal and F2X-Entry: Structurally Diverse Compound Libraries for Crystallographic Fragment Screening.
Structure, 28, 2020

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件を2024-06-26に公開中

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