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4LK4
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BU of 4lk4 by Molmil
Structure of Vibrio cholerae VesB protease
分子名称: VESB protease
著者Korotkov, K.V, Delarosa, J.R, Hol, W.G.J.
登録日2013-07-05
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Functional and Structural Characterization of Vibrio cholerae Extracellular Serine Protease B, VesB.
J.Biol.Chem., 289, 2014
4KG7
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BU of 4kg7 by Molmil
Structure of MycP3 protease from the type VII (ESX-3) secretion system.
分子名称: CHLORIDE ION, Peptidase S8 and S53, subtilisin, ...
著者Korotkov, K.V, Evans, T.J.
登録日2013-04-28
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis.
J.Struct.Biol., 184, 2013
5SXL
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BU of 5sxl by Molmil
Structure of EspG3 chaperone from the type VII (ESX-3) secretion system, space group P3221
分子名称: ESX-3 secretion-associated protein EspG3
著者Korotkov, K.V.
登録日2016-08-09
公開日2016-08-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
5VBA
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BU of 5vba by Molmil
Structure of EspG1 chaperone from the type VII (ESX-1) secretion system determined with the assistance of N-terminal T4 lysozyme fusion
分子名称: CHLORIDE ION, Lysozyme, ESX-1 secretion-associated protein EspG1 chimera
著者Korotkov, K.V.
登録日2017-03-29
公開日2017-07-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems.
J. Mol. Biol., 431, 2019
6PUX
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BU of 6pux by Molmil
Homoserine transacetylase MetX from Mycobacterium tuberculosis
分子名称: CHLORIDE ION, GLYCEROL, Homoserine O-acetyltransferase, ...
著者Chaton, C.T, Korotkov, K.V.
登録日2019-07-18
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of mycobacterial homoserine transacetylases central to methionine biosynthesis reveals druggable active site.
Sci Rep, 9, 2019
6XMV
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BU of 6xmv by Molmil
The crystal structure of Neisseria gonorrhoeae DolP (NGO1985)
分子名称: CHLORIDE ION, Hemolysin,Endolysin
著者Li, J, Peterson Brown, L.E, Reed, R.W, Wierzbicki, I.H, Sikora, A.E, Korotkov, K.V.
登録日2020-06-30
公開日2021-11-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The structure and function of a new component of Bam complex in Neisseria
To Be Published
6BLK
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BU of 6blk by Molmil
Mycobacterial sensor histidine kinase MprB
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Signal transduction histidine-protein kinase/phosphatase mprB
著者Li, J, Korotkova, N, Korotkov, K.V.
登録日2017-11-10
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.552 Å)
主引用文献Mycobacterial sensor histidine kinase MprB
to be published
5DEO
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BU of 5deo by Molmil
Mycobacterium abscessus NadD in complex with nicotinic acid adenine dinucleotide
分子名称: NICOTINIC ACID ADENINE DINUCLEOTIDE, Nicotinate-nucleotide adenylyltransferase
著者Reed, R.W, Korotkov, K.V, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2015-08-25
公開日2016-08-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Mycobacterium abscessus NadD in complex with nicotinic acid adenine dinucleotide
to be published
5DB4
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BU of 5db4 by Molmil
Mycobacterium abscessus NadD in complex with Mg-ATP, space group I41
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nicotinate-nucleotide adenylyltransferase
著者Reed, R.W, Korotkov, K.V, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2015-08-20
公開日2016-08-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Mycobacterium abscessus NadD in complex with Mg-ATP, space group I41
to be published
5I01
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BU of 5i01 by Molmil
Structure of phosphoheptose isomerase GmhA from Neisseria gonorrhoeae
分子名称: Phosphoheptose isomerase, ZINC ION
著者Wierzbicki, I.H, Sikora, A.E, Korotkov, K.V.
登録日2016-02-03
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Functional and structural studies on the Neisseria gonorrhoeae GmhA, the first enzyme in the glycero-manno-heptose biosynthesis pathways, demonstrate a critical role in lipooligosaccharide synthesis and gonococcal viability.
Microbiologyopen, 6, 2017
6O93
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BU of 6o93 by Molmil
D-alanyl transferase DltD from Enterococcus faecalis
分子名称: CHLORIDE ION, D-alanyl transferase DltD, GLYCEROL, ...
著者Shakhashiro, M, Korotkov, K.V.
登録日2019-03-12
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.178 Å)
主引用文献D-alanyl transferase DltD from Enterococcus faecalis
To Be Published
6PFX
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BU of 6pfx by Molmil
D-alanyl transferase DltD from Enterococcus faecium
分子名称: D-alanyl transferase DltD, GLYCEROL
著者Shakhashiro, M, Korotkov, K.V.
登録日2019-06-22
公開日2019-07-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献D-alanyl transferase DltD from Enterococcus faecium
To Be Published
6DGM
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BU of 6dgm by Molmil
Streptococcus pyogenes phosphoglycerol transferase GacH in complex with sn-glycerol-1-phosphate
分子名称: CALCIUM ION, MANGANESE (II) ION, Phosphoglycerol transferase GacH, ...
著者Edgar, R.J, Korotkova, N, Korotkov, K.V.
登録日2018-05-17
公開日2018-06-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides.
Nat.Chem.Biol., 15, 2019
6DQ3
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BU of 6dq3 by Molmil
Streptococcus pyogenes deacetylase PplD in complex with acetate
分子名称: 1,2-ETHANEDIOL, ACETATE ION, IMIDAZOLE, ...
著者Li, J, Korotkova, N, Korotkov, K.V.
登録日2018-06-10
公開日2019-05-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献PplD is a de-N-acetylase of the cell wall linkage unit of streptococcal rhamnopolysaccharides
Nat Commun, 13, 2022
6VHR
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BU of 6vhr by Molmil
Structure of PE5-PPE4-EspG3 complex from the type VII (ESX-3) secretion system, space group I422
分子名称: ESX-3 secretion-associated protein EspG3, PE family immunomodulator PE5, PPE family protein PPE4
著者Williamson, Z.A, Korotkov, K.V.
登録日2020-01-10
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献PE5-PPE4-EspG3heterotrimer structure from mycobacterial ESX-3 secretion system gives insight into cognate substrate recognition by ESX systems.
J.Biol.Chem., 295, 2020
6UUJ
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BU of 6uuj by Molmil
Structure of PE5-PPE4-EspG3 complex from the type VII (ESX-3) secretion system, space group P212121
分子名称: ESX-3 secretion-associated protein EspG3, PE family immunomodulator PE5, PPE family protein PPE4
著者Williamson, Z.A, Korotkov, K.V.
登録日2019-10-30
公開日2020-01-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献PE5-PPE4-EspG3heterotrimer structure from mycobacterial ESX-3 secretion system gives insight into cognate substrate recognition by ESX systems.
J.Biol.Chem., 295, 2020
6BQM
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BU of 6bqm by Molmil
Secreted serine protease VesC from Vibrio cholerae
分子名称: serine protease VesC
著者Park, Y.J, Korotkov, K.V, Delarosa, J.R, Turley, S, DiMaio, F, Hol, W.G.J.
登録日2017-11-28
公開日2018-11-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Suppressor Mutations in Type II Secretion Mutants of Vibrio cholerae: Inactivation of the VesC Protease.
Msphere, 5, 2020
6VJ5
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BU of 6vj5 by Molmil
Structure of PE25-PPE41(A124L) in complex with EspG5 chaperone from the type VII (ESX-5) secretion system
分子名称: CHLORIDE ION, ESX-5 secretion-associated protein EspG5, PE-PGRS family protein PE25, ...
著者Williamson, Z.A, Korotkov, K.V.
登録日2020-01-14
公開日2021-01-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis of diverse substrate recognition by EspG5 chaperone from mycobacterial ESX-5 Type VII Secretion System.
To Be Published
6BUV
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BU of 6buv by Molmil
Structure of Mycobacterium tuberculosis NadD in complex with inhibitor [(1~{R},2~{R},5~{S})-5-methyl-2-propan-2-yl-cyclohexyl] 2-[3-methyl-2-(phenoxymethyl)benzimidazol-1-yl]ethanoate
分子名称: 1-methyl-3-(2-{[(1R,2R,5S)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxoethyl)-2-(phenoxymethyl)-1H-1,3-benzimidazol-3-ium, CHLORIDE ION, SODIUM ION, ...
著者Rodionova, I.A, Reed, R.W, Sorci, L, Osterman, A.L, Korotkov, K.V.
登録日2017-12-11
公開日2018-12-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Novel Antimycobacterial Compounds Suppress NAD Biogenesis by Targeting a Unique Pocket of NaMN Adenylyltransferase.
Acs Chem.Biol., 14, 2019
3CFI
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BU of 3cfi by Molmil
Nanobody-aided structure determination of the EPSI:EPSJ pseudopilin heterdimer from Vibrio Vulnificus
分子名称: CHLORIDE ION, Nanobody NBEPSIJ_11, Type II secretory pathway, ...
著者Lam, A.Y, Pardon, E, Korotkov, K.V, Steyaert, J, Hol, W.G.J.
登録日2008-03-03
公開日2009-01-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Nanobody-aided structure determination of the EpsI:EpsJ pseudopilin heterodimer from Vibrio vulnificus.
J.Struct.Biol., 166, 2009
3C1Q
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BU of 3c1q by Molmil
The three-dimensional structure of the cytoplasmic domains of EpsF from the Type 2 Secretion System of Vibrio cholerae
分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CALCIUM ION, CHLORIDE ION, ...
著者Abendroth, J, Mitchell, D.D, Korotkov, K.V, Kreeger, A, Hol, W.G.J.
登録日2008-01-24
公開日2009-02-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The three-dimensional structure of the cytoplasmic domains of EpsF from the type 2 secretion system of Vibrio cholerae
J.Struct.Biol., 166, 2009
4XY3
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BU of 4xy3 by Molmil
Structure of ESX-1 secreted protein EspB
分子名称: ESX-1 secretion-associated protein EspB
著者Wagner, J.M, Korotkov, K.V.
登録日2015-02-01
公開日2015-02-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
4XXX
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BU of 4xxx by Molmil
Structure of PE-PPE domains of ESX-1 secreted protein EspB, C2221
分子名称: CHLORIDE ION, ESX-1 secretion-associated protein EspB, GLYCEROL
著者Piton, J, Pojer, F, Korotkov, K.V.
登録日2015-01-30
公開日2015-02-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.
J.Struct.Biol., 191, 2015
6CYZ
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BU of 6cyz by Molmil
Mycobacterial homoserine kinase ThrB in complex with AMPPNP
分子名称: CHLORIDE ION, Homoserine kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Li, J, Korotkov, K.V.
登録日2018-04-07
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Mycobacterial homoserine kinase ThrB
To Be Published
6DZS
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BU of 6dzs by Molmil
Mycobacterial homoserine dehydrogenase ThrA in complex with NADP
分子名称: Homoserine dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Chaton, C.T, Rodriguez, E.S, Korotkov, K.V.
登録日2018-07-05
公開日2018-07-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structure of mycobacterial homoserine dehydrogenase ThrA
To be Published

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