4Z2S
| The crystal structure of Sclerotium Rolfsii lectin variant 2 (SSR2) in complex with N-acetyl-glucosamine | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ... | 著者 | Kantsadi, A.L, Peppa, V.I, Leonidas, D.D. | 登録日 | 2015-03-30 | 公開日 | 2015-07-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants. Molecules, 20, 2015
|
|
4Z2F
| Sclerotium Rolfsii lectin variant (SSR2) with fine carbohydrate specificity | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, lectin variant 2 | 著者 | Kantsadi, A.L, Peppa, V.I, Leonidas, D.D. | 登録日 | 2015-03-29 | 公開日 | 2015-07-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants. Molecules, 20, 2015
|
|
4Z2Q
| The crystal structure of Sclerotium Rolfsii lectin variant 1 (SSR1) in complex with N-acetyl-glucosamine | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ... | 著者 | Kantsadi, A.L, Peppa, V.I, Leonidas, D.D. | 登録日 | 2015-03-30 | 公開日 | 2015-07-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants. Molecules, 20, 2015
|
|
5O52
| Glycogen Phosphorylase b in complex with 33b | 分子名称: | (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(4-naphthalen-2-yl-1~{H}-imidazol-2-yl)oxane-3,4-diol, Glycogen phosphorylase, muscle form, ... | 著者 | Kantsadi, A.L, Kyriakis, E, Stravodimos, G.A, Solovou, T.G.A, Chatzileontiadou, D.S, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2017-05-31 | 公開日 | 2017-09-27 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Nanomolar Inhibitors of Glycogen Phosphorylase Based on beta-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study. J. Med. Chem., 60, 2017
|
|
5O50
| Glycogen Phosphorylase b in complex with 33a | 分子名称: | (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(4-phenyl-1~{H}-imidazol-2-yl)oxane-3,4-diol, Glycogen phosphorylase, muscle form, ... | 著者 | Kantsadi, A.L, Kyriakis, E, Stravodimos, G.A, Solovou, T.G.A, Chatzileontiadou, D.S, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2017-05-31 | 公開日 | 2017-09-27 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Nanomolar Inhibitors of Glycogen Phosphorylase Based on beta-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study. J. Med. Chem., 60, 2017
|
|
4YLD
| The crystal structure of Sclerotium Rolfsii lectin variant 1 (SSR1) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Sclerotium Rolfsii lectin variant 1 (SSR1) | 著者 | Kantsadi, A.L, Peppa, V.I, Leonidas, D.D. | 登録日 | 2015-03-05 | 公開日 | 2015-07-01 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants. Molecules, 20, 2015
|
|
5OX3
| Glycogen Phosphorylase in complex with SzB102v | 分子名称: | (1S)-1,5-anhydro-1-[3-(4-hydroxyphenyl)-1H-1,2,4-triazol-5-yl]-D-glucitol, Glycogen phosphorylase, muscle form, ... | 著者 | Kyriakis, E, Stravodimos, G.A, Kantsadi, A.L, Chatzileontiadou, D.S.M, Leonidas, D.D. | 登録日 | 2017-09-05 | 公開日 | 2018-02-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Probing the beta-pocket of the active site of human liver glycogen phosphorylase with 3-(C-beta-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors. Bioorg. Chem., 77, 2018
|
|
5OX4
| Glycogen Phosphorylase in complex with CK900 | 分子名称: | (2~{S},3~{R},4~{R},5~{S},6~{R})-2-[5-(4-aminophenyl)-4~{H}-1,2,4-triazol-3-yl]-6-(hydroxymethyl)oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... | 著者 | Kyriakis, E, Stravodimos, G.A, Kantsadi, A.L, Chatzileontiadou, D.S.M, Leonidas, D.D. | 登録日 | 2017-09-05 | 公開日 | 2018-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Probing the beta-pocket of the active site of human liver glycogen phosphorylase with 3-(C-beta-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors. Bioorg. Chem., 77, 2018
|
|
5OX0
| Glycogen Phosphorylase in complex with CK898 | 分子名称: | (1S)-1,5-anhydro-1-(3-{4-[hydroxy(oxo)azaniumyl]phenyl}-1H-1,2,4-triazol-5-yl)-D-glucitol, Glycogen phosphorylase, muscle form, ... | 著者 | Kyriakis, E, Stravodimos, G.A, Kantsadi, A.L, Chatzileontiadou, D.S.M, Leonidas, D.D. | 登録日 | 2017-09-05 | 公開日 | 2018-02-28 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Probing the beta-pocket of the active site of human liver glycogen phosphorylase with 3-(C-beta-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors. Bioorg. Chem., 77, 2018
|
|
5OWZ
| Glycogen Phosphorylase in complex with KS172 | 分子名称: | (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-[5-[4-(trifluoromethyl)phenyl]-4~{H}-1,2,4-triazol-3-yl]oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... | 著者 | Kyriakis, E, Stravodimos, G.A, Kantsadi, A.L, Chatzileontiadou, D.S.M, Leonidas, D.D. | 登録日 | 2017-09-05 | 公開日 | 2018-02-28 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Probing the beta-pocket of the active site of human liver glycogen phosphorylase with 3-(C-beta-d-glucopyranosyl)-5-(4-substituted-phenyl)-1, 2, 4-triazole inhibitors. Bioorg. Chem., 77, 2018
|
|
7OOE
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z321318226 | 分子名称: | AMP PHOSPHORAMIDATE, CHLORIDE ION, GLYCEROL, ... | 著者 | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | 登録日 | 2021-05-27 | 公開日 | 2021-06-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.369 Å) | 主引用文献 | Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published
|
|
7OOH
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 | 分子名称: | 4-IODOPYRAZOLE, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... | 著者 | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | 登録日 | 2021-05-27 | 公開日 | 2021-06-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 To Be Published
|
|
7OOG
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023823 | 分子名称: | 4-bromanylpyridin-2-amine, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... | 著者 | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | 登録日 | 2021-05-27 | 公開日 | 2021-06-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023823 To Be Published
|
|
7P31
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 | 分子名称: | 4-IODOPYRAZOLE, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... | 著者 | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | 登録日 | 2021-07-06 | 公開日 | 2021-07-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with small molecule ligands To Be Published
|
|
7ZLL
| Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with the 5-[(morpholin-4-yl)methyl]quinolin-8-ol inhibitor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-(morpholin-4-ylmethyl)quinolin-8-ol, UDP-glucose-glycoprotein glucosyltransferase-like protein, ... | 著者 | Roversi, P, Zitzmann, N, Bayo, Y, Kantsadi, A.L, Chandran, A.V. | 登録日 | 2022-04-15 | 公開日 | 2023-04-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.649 Å) | 主引用文献 | A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint. Iscience, 26, 2023
|
|
4G8Y
| Crystal structure of Ribonuclease A in complex with 5b | 分子名称: | 1-{[1-(alpha-L-arabinofuranosyl)-1H-1,2,3-triazol-4-yl]methyl}-5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine, Ribonuclease pancreatic | 著者 | Chatzileontiadou, D.S.M, Kantsadi, A.L, Leonidas, D.D. | 登録日 | 2012-07-23 | 公開日 | 2012-11-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation. Bioorg.Med.Chem., 20, 2012
|
|
4G90
| Crystal structure of Ribonuclease A in complex with 5e | 分子名称: | 1-{[1-(alpha-L-arabinofuranosyl)-1H-1,2,3-triazol-4-yl]methyl}-5-fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidine, Ribonuclease pancreatic | 著者 | Chatzileontiadou, D.S.M, Kantsadi, A.L, Leonidas, D.D. | 登録日 | 2012-07-23 | 公開日 | 2012-11-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation. Bioorg.Med.Chem., 20, 2012
|
|
4G9M
| |
4G8V
| Crystal structure of Ribonuclease A in complex with 5a | 分子名称: | 1-{[1-(alpha-L-arabinofuranosyl)-1H-1,2,3-triazol-4-yl]methyl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidine, Ribonuclease pancreatic | 著者 | Chatzileontiadou, D.S.M, Kantsadi, A.L, Leonidas, D.D. | 登録日 | 2012-07-23 | 公開日 | 2012-11-21 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation. Bioorg.Med.Chem., 20, 2012
|
|
4G9N
| |
7NQZ
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z1827898537 | 分子名称: | (3S)-N-benzylpyrrolidin-3-amine, AMP PHOSPHORAMIDATE, CHLORIDE ION, ... | 著者 | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | 登録日 | 2021-03-02 | 公開日 | 2021-03-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.319 Å) | 主引用文献 | Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published
|
|
7NQR
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z287256168 | 分子名称: | (S)-N-(1-cyclopropylethyl)-6-methylpicolinamide, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, AMP PHOSPHORAMIDATE, ... | 著者 | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | 登録日 | 2021-03-02 | 公開日 | 2021-03-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published
|
|
7NQU
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z396380540 | 分子名称: | AMP PHOSPHORAMIDATE, CHLORIDE ION, GLYCEROL, ... | 著者 | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | 登録日 | 2021-03-02 | 公開日 | 2021-03-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published
|
|
7NQS
| Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z1203107138 | 分子名称: | 1-ethyl-N-[(4-fluorophenyl)methyl]-1H-pyrazole-4-carboxamide, AMP PHOSPHORAMIDATE, GLYCEROL, ... | 著者 | Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I. | 登録日 | 2021-03-02 | 公開日 | 2021-03-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published
|
|
5E13
| Crystal structure of Eosinophil-derived neurotoxin in complex with the triazole double-headed ribonucleoside 11c | 分子名称: | 3'-{4-[(4-amino-2-oxopyrimidin-1(2H)-yl)methyl]-1H-1,2,3-triazol-1-yl}-3'-deoxyadenosine, Non-secretory ribonuclease | 著者 | Chatzileontiadou, D.S.M, Stravodimos, G.A, Kantsadi, A.L, Leonidas, D.D. | 登録日 | 2015-09-29 | 公開日 | 2015-11-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Triazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin. Bioorg.Chem., 63, 2015
|
|