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4R9L
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BU of 4r9l by Molmil
Structure of a thermostable elevenfold mutant of limonene epoxide hydrolase from Rhodococcus erythropolis, containing two stabilizing disulfide bonds
分子名称: (2R)-2-hydroxyhexanamide, Limonene-1,2-epoxide hydrolase
著者Floor, R.J, Wijma, H.J, Jekel, P.A, Terwisscha van Scheltinga, A.C, Dijkstra, B.W, Janssen, D.B.
登録日2014-09-05
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray crystallographic validation of structure predictions used in computational design for protein stabilization.
Proteins, 83, 2015
3ZN2
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BU of 3zn2 by Molmil
protein engineering of halohydrin dehalogenase
分子名称: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ACETATE ION, HALOHYDRIN DEHALOGENASE, ...
著者Schallmey, M, Jekel, P, Tang, L, Majeric-Elenkov, M, Hoeffken, H.W, Hauer, B, Janssen, D.B.
登録日2013-02-13
公開日2014-03-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Single Point Mutation Enhances Hydroxynitrile Synthesis by Halohydrin Dehalogenase.
Enzyme.Microb.Technol., 70, 2015
3ZVH
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BU of 3zvh by Molmil
Methylaspartate ammonia lyase from Clostridium tetanomorphum mutant Q73A
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Raj, H, Szymanski, W, de Villiers, J, Rozeboom, H.J, Veetil, V.P, Reis, C.R, de Villiers, M, de Wildeman, S, Dekker, F.J, Quax, W.J, Thunnissen, A.M.W.H, Feringa, B.L, Janssen, D.B, Poelarends, G.J.
登録日2011-07-25
公開日2012-05-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Engineering Methylaspartate Ammonia Lyase for the Asymmetric Synthesis of Unnatural Amino Acids.
Nat.Chem., 4, 2012
3ZVI
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BU of 3zvi by Molmil
Methylaspartate ammonia lyase from Clostridium tetanomorphum mutant L384A
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Raj, H, Szymanski, W, de Villiers, J, Rozeboom, H.J, Veetil, V.P, Reis, C.R, de Villiers, M, de Wildeman, S, Dekker, F.J, Quax, W.J, Thunnissen, A.M.W.H, Feringa, B.L, Janssen, D.B, Poelarends, G.J.
登録日2011-07-25
公開日2012-05-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Engineering Methylaspartate Ammonia Lyase for the Asymmetric Synthesis of Unnatural Amino Acids.
Nat.Chem., 4, 2012
4AO4
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BU of 4ao4 by Molmil
Structural Determinants of the beta-Selectivity of a Bacterial Aminotransferase
分子名称: (3R)-3-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]-5-METHYLHEXANOIC ACID, 1,2-ETHANEDIOL, Beta-transaminase
著者Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W.
登録日2012-03-23
公開日2012-06-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural determinants of the beta-selectivity of a bacterial aminotransferase.
J. Biol. Chem., 287, 2012
4AO9
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BU of 4ao9 by Molmil
Biochemical properties and crystal structure of a novel beta- phenylalanine aminotransferase from Variovorax paradoxus
分子名称: BETA-PHENYLALANINE AMINOTRANSFERASE, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE
著者Crismaru, C.G, Wybenga, G.G, Szymanski, W, Wijma, H.J, Wu, B, deWildeman, S, Poelarends, G.J, Dijkstra, B.W, Janssen, D.B.
登録日2012-03-25
公開日2012-10-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Biochemical Properties and Crystal Structure of a Novel Beta-Phenylalanine Aminotransferase from Variovorax Paradoxus
Appl.Environ.Microbiol., 79, 2013
4AOA
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BU of 4aoa by Molmil
Biochemical properties and crystal structure of a novel beta- phenylalanine aminotransferase from Variovorax paradoxus
分子名称: 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, BETA-PHENYLALANINE AMINOTRANSFERASE, GLYCEROL
著者Crismaru, C.G, Wybenga, G.G, Szymanski, W, Wijma, H.J, Wu, B, deWildeman, S, Poelarends, G.J, Dijkstra, B.W, Janssen, D.B.
登録日2012-03-25
公開日2012-10-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Biochemical Properties and Crystal Structure of a Beta-Phenylalanine Aminotransferase from Variovorax Paradoxus.
Appl.Environ.Microbiol., 79, 2013
4BAA
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BU of 4baa by Molmil
Redesign of a Phenylalanine Aminomutase into a beta-Phenylalanine Ammonia Lyase
分子名称: PHENYLALANINE AMMONIA-LYASE
著者Bartsch, S, Wybenga, G.G, Jansen, M, Heberling, M.M, Wu, B, Dijkstra, B.W, Janssen, D.B.
登録日2012-09-12
公開日2013-01-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Redesign of a Phenylalanine Aminomutase Into a Phenylalanine Ammonia Lyase
To be Published
1PX0
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BU of 1px0 by Molmil
Crystal structure of the haloalcohol dehalogenase HheC complexed with the haloalcohol mimic (R)-1-para-nitro-phenyl-2-azido-ethanol
分子名称: (R)-1-PARA-NITRO-PHENYL-2-AZIDO-ETHANOL, halohydrin dehalogenase
著者de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W.
登録日2003-07-02
公開日2003-10-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site
EMBO J., 22, 2003
1NX9
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BU of 1nx9 by Molmil
Acetobacter turbidans alpha-amino acid ester hydrolase S205A mutant complexed with ampicillin
分子名称: (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, GLYCEROL, alpha-amino acid ester hydrolase
著者Barends, T.R.M, Polderman-Tijmes, J.J, Jekel, P.A, Janssen, D.B, Dijkstra, B.W.
登録日2003-02-10
公開日2004-03-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Acetobacter turbidans {alpha}-Amino Acid Ester Hydrolase: HOW A SINGLE MUTATION IMPROVES AN ANTIBIOTIC-PRODUCING ENZYME.
J.Biol.Chem., 281, 2006
1PWZ
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BU of 1pwz by Molmil
Crystal structure of the haloalcohol dehalogenase HheC complexed with (R)-styrene oxide and chloride
分子名称: CHLORIDE ION, R-STYRENE OXIDE, halohydrin dehalogenase
著者de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W.
登録日2003-07-02
公開日2003-10-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site
EMBO J., 22, 2003
1PWX
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BU of 1pwx by Molmil
Crystal structure of the haloalcohol dehalogenase HheC complexed with bromide
分子名称: BROMIDE ION, halohydrin dehalogenase
著者de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W.
登録日2003-07-02
公開日2003-10-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site
EMBO J., 22, 2003
6T8F
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BU of 6t8f by Molmil
Crystal structure of mutant xylose isomerase (V270A/A273G) from Piromyces E2 grown in yeast, in complex with xylose
分子名称: CALCIUM ION, D-xylose, SULFATE ION, ...
著者Rozeboom, H.J, Janssen, D.B.
登録日2019-10-24
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-based directed evolution improves S. cerevisiae growth on xylose by influencing in vivo enzyme performance.
Biotechnol Biofuels, 13, 2020
6TB0
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BU of 6tb0 by Molmil
Crystal structure of thermostable omega transaminase 4-fold mutant from Pseudomonas jessenii
分子名称: Aspartate aminotransferase family protein, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ...
著者Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B.
登録日2019-10-31
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Robust omega-Transaminases by Computational Stabilization of the Subunit Interface.
Acs Catalysis, 10, 2020
6T8E
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BU of 6t8e by Molmil
Crystal structure of native xylose isomerase from Piromyces E2 grown in yeast, in complex with xylose
分子名称: CALCIUM ION, D-xylose, SULFATE ION, ...
著者Rozeboom, H.J, Janssen, D.B.
登録日2019-10-24
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structure-based directed evolution improves S. cerevisiae growth on xylose by influencing in vivo enzyme performance.
Biotechnol Biofuels, 13, 2020
6TB1
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BU of 6tb1 by Molmil
Crystal structure of thermostable omega transaminase 6-fold mutant from Pseudomonas jessenii
分子名称: Aspartate aminotransferase family protein, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ...
著者Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B.
登録日2019-10-31
公開日2020-07-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Robust omega-Transaminases by Computational Stabilization of the Subunit Interface.
Acs Catalysis, 10, 2020
6TP0
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BU of 6tp0 by Molmil
Crystal structure of Bacillus paralicheniformis alpha-amylase in complex with maltose
分子名称: ACETIC ACID, Amylase, CALCIUM ION, ...
著者Rozeboom, H.J, Janssen, D.B.
登録日2019-12-12
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Characterization of the starch surface binding site on Bacillus paralicheniformis alpha-amylase.
Int.J.Biol.Macromol., 165, 2020
6TOY
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BU of 6toy by Molmil
Crystal structure of Bacillus paralicheniformis wild-type alpha-amylase
分子名称: ACETIC ACID, Amylase, CALCIUM ION, ...
著者Rozeboom, H.J, Janssen, D.B.
登録日2019-12-12
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Characterization of the starch surface binding site on Bacillus paralicheniformis alpha-amylase.
Int.J.Biol.Macromol., 165, 2020
6TP1
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BU of 6tp1 by Molmil
Crystal structure of Bacillus paralicheniformis alpha-amylase in complex with maltotetraose
分子名称: ACETIC ACID, Amylase, CALCIUM ION, ...
著者Rozeboom, H.J, Janssen, D.B.
登録日2019-12-12
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Characterization of the starch surface binding site on Bacillus paralicheniformis alpha-amylase.
Int.J.Biol.Macromol., 165, 2020
6TP2
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BU of 6tp2 by Molmil
Crystal structure of Bacillus paralicheniformis alpha-amylase in complex with beta-cyclodextrin
分子名称: Amylase, CALCIUM ION, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), ...
著者Rozeboom, H.J, Janssen, D.B.
登録日2019-12-12
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Characterization of the starch surface binding site on Bacillus paralicheniformis alpha-amylase.
Int.J.Biol.Macromol., 165, 2020
6TOZ
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BU of 6toz by Molmil
Crystal structure of Bacillus paralicheniformis alpha-amylase in complex with acarbose
分子名称: 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ACETIC ACID, Amylase, ...
著者Rozeboom, H.J, Janssen, D.B.
登録日2019-12-12
公開日2020-10-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Characterization of the starch surface binding site on Bacillus paralicheniformis alpha-amylase.
Int.J.Biol.Macromol., 165, 2020
2YKU
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BU of 2yku by Molmil
Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase
分子名称: 1,2-ETHANEDIOL, BETA-TRANSAMINASE, GLYCEROL, ...
著者Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W.
登録日2011-05-30
公開日2012-05-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase.
J.Biol.Chem., 287, 2012
2YKY
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BU of 2yky by Molmil
Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase
分子名称: (3S)-3-amino-3-phenylpropanoic acid, 1,2-ETHANEDIOL, BENZENE, ...
著者Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W.
登録日2011-05-30
公開日2012-05-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase.
J.Biol.Chem., 287, 2012
2YKV
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BU of 2ykv by Molmil
Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase
分子名称: 1,2-ETHANEDIOL, 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, BETA-TRANSAMINASE
著者Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W.
登録日2011-05-30
公開日2012-05-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase.
J.Biol.Chem., 287, 2012
2YKX
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BU of 2ykx by Molmil
Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase
分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, BETA-TRANSAMINASE, ...
著者Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W.
登録日2011-05-30
公開日2012-05-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase.
J.Biol.Chem., 287, 2012

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