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3PG0
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BU of 3pg0 by Molmil
Crystal structure of designed 3-fold symmetric protein, ThreeFoil
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, SODIUM ION, ...
著者Lobsanov, Y.D, Broom, A, Howell, P.L, Rose, D.R, Meiering, E.M.
登録日2010-10-29
公開日2011-12-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Modular evolution and the origins of symmetry: reconstruction of a three-fold symmetric globular protein.
Structure, 20, 2012
4DN0
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PelD 156-455 from Pseudomonas aeruginosa PA14 in complex with c-di-GMP
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Putative uncharacterized protein pelD, SODIUM ION, ...
著者Whitney, J.C, Colvin, K.M, Marmont, L.S, Robinson, H, Parsek, M.R, Howell, P.L.
登録日2012-02-08
公開日2012-05-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the Cytoplasmic Region of PelD, a Degenerate Diguanylate Cyclase Receptor That Regulates Exopolysaccharide Production in Pseudomonas aeruginosa.
J.Biol.Chem., 287, 2012
4DMZ
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PelD 156-455 from Pseudomonas aeruginosa PA14, apo form
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ...
著者Whitney, J.C, Colvin, K.M, Marmont, L.S, Robinson, H, Parsek, M.R, Howell, P.L.
登録日2012-02-08
公開日2012-05-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Structure of the Cytoplasmic Region of PelD, a Degenerate Diguanylate Cyclase Receptor That Regulates Exopolysaccharide Production in Pseudomonas aeruginosa.
J.Biol.Chem., 287, 2012
4F9D
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BU of 4f9d by Molmil
Structure of Escherichia coli PgaB 42-655 in complex with nickel
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETIC ACID, CALCIUM ION, ...
著者Little, D.J, Poloczek, J, Whitney, J.C, Robinson, H, Nitz, M, Howell, P.L.
登録日2012-05-18
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Structure and Metal Dependent Activity of Escherichia coli PgaB Provides Insight into the Partial De-N-acetylation of Poly-b-1,6-N-acetyl-D-glucosamine
J.Biol.Chem., 287, 2012
4F9J
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Structure of Escherichia coli PgaB 42-655 in complex with iron
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETIC ACID, CALCIUM ION, ...
著者Little, D.J, Poloczek, J, Whitney, J.C, Robinson, H, Nitz, M, Howell, P.L.
登録日2012-05-18
公開日2012-07-25
最終更新日2013-06-26
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献The Structure and Metal Dependent Activity of Escherichia coli PgaB Provides Insight into the Partial De-N-acetylation of Poly-b-1,6-N-acetyl-D-glucosamine
J.Biol.Chem., 287, 2012
4WCJ
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BU of 4wcj by Molmil
Structure of IcaB from Ammonifex degensii
分子名称: CHLORIDE ION, Polysaccharide deacetylase, ZINC ION
著者Little, D.J, Bamford, N.C, Pokrovskaya, V, Robinson, H, Nitz, M, Howell, P.L.
登録日2014-09-04
公開日2014-11-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Basis for the De-N-acetylation of Poly-beta-1,6-N-acetyl-d-glucosamine in Gram-positive Bacteria.
J.Biol.Chem., 289, 2014
4ICG
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BU of 4icg by Molmil
N-terminal dimerization domain of H-NS in complex with Hha (Salmonella Typhimurium)
分子名称: DNA-binding protein H-NS, Hemolysin expression modulating protein (Involved in environmental regulation of virulence factors)
著者Ali, S.S, Whitney, J.C, Stevenson, J, Robinson, H, Howell, P.L, Navarre, W.W.
登録日2012-12-10
公開日2013-03-27
最終更新日2016-05-18
実験手法X-RAY DIFFRACTION (2.9217 Å)
主引用文献Structural Insights into the Regulation of Foreign Genes in Salmonella by the Hha/H-NS Complex.
J.Biol.Chem., 288, 2013
4KNC
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BU of 4knc by Molmil
Structural and functional characterization of Pseudomonas aeruginosa AlgX
分子名称: Alginate biosynthesis protein AlgX
著者Riley, L.M, Weadge, J.T, Baker, P, Robinson, H, Codee, J.D.C, Tipton, P.A, Ohman, D.E, Howell, P.L.
登録日2013-05-09
公開日2013-06-26
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.141 Å)
主引用文献Structural and Functional Characterization of Pseudomonas aeruginosa AlgX: ROLE OF AlgX IN ALGINATE ACETYLATION.
J.Biol.Chem., 288, 2013
3BL6
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BU of 3bl6 by Molmil
Crystal structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in complex with formycin A
分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteine nucleosidase
著者Siu, K.K.W, Lee, J.E, Smith, G.D, Horvatin, C, Howell, P.L.
登録日2007-12-10
公開日2008-06-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Acta Crystallogr.,Sect.F, 64, 2008
3CQT
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BU of 3cqt by Molmil
N53I V55L MUTANT of FYN SH3 DOMAIN
分子名称: Proto-oncogene tyrosine-protein kinase Fyn
著者Neculai, A.M, Zarrine-Afsar, A, Howell, P.L, Davidson, A, Chan, H.S.
登録日2008-04-03
公開日2008-07-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3DF9
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BU of 3df9 by Molmil
Crystal structure of E. coli MTA/SAH nucleosidase in complex with BnT-DADMeImmA
分子名称: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(benzylsulfanyl)methyl]pyrrolidin-3-ol, MTA/SAH nucleosidase
著者Siu, K.K.W, Howell, P.L.
登録日2008-06-11
公開日2009-03-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Acta Crystallogr.,Sect.F, 64, 2008
3FZ2
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BU of 3fz2 by Molmil
Crystal structure of the tail terminator protein from phage lambda (gpU-D74A)
分子名称: Minor tail protein U, SULFATE ION
著者Pell, L.G, Liu, A, Edmonds, E, Donaldson, L.W, Howell, P.L, Davidson, A.R.
登録日2009-01-23
公開日2009-05-26
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The X-ray crystal structure of the phage lambda tail terminator protein reveals the biologically relevant hexameric ring structure and demonstrates a conserved mechanism of tail termination among diverse long-tailed phages.
J.Mol.Biol., 389, 2009
3FZB
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BU of 3fzb by Molmil
Crystal structure of the tail terminator protein from phage lambda (gpU-WT)
分子名称: Minor tail protein U, SULFATE ION
著者Pell, L.G, Liu, A, Edmonds, E, Donaldson, L.W, Howell, P.L, Davidson, A.R.
登録日2009-01-24
公開日2009-05-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The X-ray crystal structure of the phage lambda tail terminator protein reveals the biologically relevant hexameric ring structure and demonstrates a conserved mechanism of tail termination among diverse long-tailed phages.
J.Mol.Biol., 389, 2009
6VE4
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BU of 6ve4 by Molmil
Pentadecameric PilQ from Pseudomonas aeruginosa
分子名称: Fimbrial assembly protein PilQ
著者McCallum, M, Tammam, S, Rubinstein, J.L, Burrows, L.L, Howell, P.L.
登録日2019-12-28
公開日2020-12-23
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献CryoEM map of Pseudomonas aeruginosa PilQ enables structural characterization of TsaP.
Structure, 29, 2021
1A7A
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BU of 1a7a by Molmil
STRUCTURE OF HUMAN PLACENTAL S-ADENOSYLHOMOCYSTEINE HYDROLASE: DETERMINATION OF A 30 SELENIUM ATOM SUBSTRUCTURE FROM DATA AT A SINGLE WAVELENGTH
分子名称: (1'R,2'S)-9-(2-HYDROXY-3'-KETO-CYCLOPENTEN-1-YL)ADENINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-ADENOSYLHOMOCYSTEINE HYDROLASE
著者Turner, M.A, Yuan, C.-S, Borchardt, R.T, Hershfield, M.S, Smith, G.D, Howell, P.L.
登録日1998-03-10
公開日1999-04-20
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure determination of selenomethionyl S-adenosylhomocysteine hydrolase using data at a single wavelength.
Nat.Struct.Biol., 5, 1998
6AU1
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BU of 6au1 by Molmil
Structure of the PgaB (BpsB) glycoside hydrolase domain from Bordetella bronchiseptica
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Putative hemin storage protein, ...
著者Little, D.J, Bamford, N.C, Howell, P.L.
登録日2017-08-30
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-beta (1,6)-N-acetylglucosamine and can disrupt bacterial biofilms.
PLoS Pathog., 14, 2018
6BT4
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BU of 6bt4 by Molmil
Crystal structure of the SLH domain of Sap from Bacillus anthracis in complex with a pyruvylated SCWP unit
分子名称: 2-(acetylamino)-4-O-{2-(acetylamino)-4,6-O-[(1S)-1-carboxyethylidene]-2-deoxy-beta-D-mannopyranosyl}-2-deoxy-beta-D-glucopyranose, S-layer protein sap, SULFATE ION
著者Sychantha, D, Chapman, R.N, Bamford, N.C, Boons, G.J, Howell, P.L, Clarke, A.J.
登録日2017-12-05
公開日2018-03-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献Molecular Basis for the Attachment of S-Layer Proteins to the Cell Wall of Bacillus anthracis.
Biochemistry, 57, 2018
1AUW
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H91N DELTA 2 CRYSTALLIN FROM DUCK
分子名称: DELTA 2 CRYSTALLIN
著者Abu-Abed, M, Vallee, F, Howell, P.L.
登録日1997-09-03
公開日1998-03-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural comparison of the enzymatically active and inactive forms of delta crystallin and the role of histidine 91.
Biochemistry, 36, 1997
1AOS
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HUMAN ARGININOSUCCINATE LYASE
分子名称: ARGININOSUCCINATE LYASE
著者Turner, M.A, Simpson, A, Mcinnes, R.R, Howell, P.L.
登録日1997-07-10
公開日1998-01-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Human argininosuccinate lyase: a structural basis for intragenic complementation.
Proc.Natl.Acad.Sci.USA, 94, 1997
6CZT
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BU of 6czt by Molmil
CS-rosetta determined structures of the N-terminal domain of AlgF from P. aeruginosa
分子名称: Alginate biosynthesis protein AlgF
著者Tammam, S, Howell, P.L.
登録日2018-04-09
公開日2019-04-17
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Pseudomonas aeruginosa AlgF is an adaptor protein required for acetylation of the alginate exopolysaccharide
To Be Published
6D10
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CS-rosetta determined structures of the C-terminal domain of AlgF from P. aeruginosa
分子名称: Alginate biosynthesis protein AlgF
著者Tammam, S, Howell, P.L.
登録日2018-04-11
公開日2019-04-17
最終更新日2024-05-01
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Pseudomonas aeruginosa AlgF is an adaptor protein required for acetylation of the alginate exopolysaccharide
To Be Published
5EOY
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Pseudomonas aeruginosa SeMet-PilM bound to ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Type 4 fimbrial biogenesis protein PilM
著者McCallum, M, Tammam, S, Robinson, H, Shah, M, Calmettes, C, Moraes, T, Burrows, L.L, Howell, P.L.
登録日2015-11-10
公開日2016-04-27
最終更新日2016-06-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM.
J.Biol.Chem., 291, 2016
5EQ6
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Pseudomonas aeruginosa PilM bound to AMP-PNP
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Type 4 fimbrial biogenesis protein PilM
著者McCallum, M, Tammam, S, Robinson, H, Shah, M, Calmettes, C, Moraes, T, Burrows, L.L, Howell, P.L.
登録日2015-11-12
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM.
J.Biol.Chem., 291, 2016
5EOX
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Pseudomonas aeruginosa PilM bound to ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Type 4 fimbrial biogenesis protein PilM
著者McCallum, M, Tammam, S, Robinson, H, Shah, M, Calmettes, C, Moraes, T, Burrows, L.L, Howell, P.L.
登録日2015-11-10
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM.
J.Biol.Chem., 291, 2016
6OJ1
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Crystal Structure of Aspergillus fumigatus Ega3
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Bamford, N.C, Subramanian, A.S, Millan, C, Uson, I, Howell, P.L.
登録日2019-04-10
公開日2019-08-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Ega3 from the fungal pathogenAspergillus fumigatusis an endo-alpha-1,4-galactosaminidase that disrupts microbial biofilms.
J.Biol.Chem., 294, 2019

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