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4GFC
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BU of 4gfc by Molmil
N-terminal coiled-coil dimer of C.elegans SAS-6, crystal form B
分子名称: 1,2-ETHANEDIOL, IMIDAZOLE, Spindle assembly abnormal protein 6, ...
著者Erat, M.C, Vakonakis, I.
登録日2012-08-03
公開日2013-06-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.
Proc.Natl.Acad.Sci.USA, 110, 2013
6YRL
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BU of 6yrl by Molmil
Structure of the Chlamydomonas reinhardtii SAS-6 coiled-coil domain, C2 crystal form
分子名称: Centriole protein
著者Kantsadi, A.L, Vakonakis, I.
登録日2020-04-20
公開日2021-05-12
最終更新日2022-03-16
実験手法X-RAY DIFFRACTION (2.343 Å)
主引用文献Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Structure, 2022
6YRN
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BU of 6yrn by Molmil
Structure of the Chlamydomonas reinhardtii SAS-6 coiled-coil domain, P2 crystal form
分子名称: Centriole protein, TETRAETHYLENE GLYCOL
著者Kantsadi, A.L, Vakonakis, I.
登録日2020-04-20
公開日2021-05-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Structure, 2022
6YS4
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BU of 6ys4 by Molmil
Structure of the Homo sapiens SAS-6 coiled-coil domain
分子名称: GLYCINE, Spindle assembly abnormal protein 6 homolog, TETRAETHYLENE GLYCOL
著者Kantsadi, A.L, Vakonakis, I.
登録日2020-04-21
公開日2021-05-12
最終更新日2022-03-16
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Structure, 2022
4TTY
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BU of 4tty by Molmil
N-terminal domain of C. Reinhardtii SAS-6 homolog bld12p G94D F145W Q147R (NN25)
分子名称: Centriole protein
著者Hilbert, M, Kraatz, S.H.W.
登録日2014-06-23
公開日2015-07-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
Nat.Cell Biol., 18, 2016
4ZTQ
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BU of 4ztq by Molmil
Human Aurora A catalytic domain bound to FK932
分子名称: (2Z,5Z)-2-[(4-ethylphenyl)imino]-3-(2-methoxyethyl)-5-(pyridin-4-ylmethylidene)-1,3-thiazolidin-4-one, (4S)-2-METHYL-2,4-PENTANEDIOL, Aurora kinase A
著者Marcaida, M.J, Kilchmann, F, Schick, T, Reymond, J.L.
登録日2015-05-14
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening.
J.Med.Chem., 59, 2016
4ZS0
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BU of 4zs0 by Molmil
Human Aurora A catalytic domain bound to SB-6-OH
分子名称: 5-hydroxy-1'H-1,2'-bibenzimidazol-2(3H)-one, Aurora kinase A
著者Marcaida, M.J, Kilchmann, F, Schick, T, Reymond, J.L.
登録日2015-05-12
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening.
J.Med.Chem., 59, 2016
4ZTS
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BU of 4zts by Molmil
Human Aurora A catalytic domain bound to FK1142
分子名称: (2Z,5Z)-2-[(4-ethylphenyl)imino]-3-methyl-5-[(2-{[4-(1H-tetrazol-5-yl)phenyl]amino}pyridin-4-yl)methylidene]-1,3-thiazolidin-4-one, (4S)-2-METHYL-2,4-PENTANEDIOL, Aurora kinase A
著者Marcaida, M.J, Kilchmann, F, Schick, T, Reymond, J.L.
登録日2015-05-15
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening.
J.Med.Chem., 59, 2016
4ZTR
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BU of 4ztr by Molmil
Human Aurora A catalytic domain bound to FK1141
分子名称: 6-({4-[(Z)-{(2Z)-2-[(4-ethylphenyl)imino]-3-methyl-4-oxo-1,3-thiazolidin-5-ylidene}methyl]pyridin-2-yl}amino)pyridine-3-carboxylic acid, Aurora kinase A
著者Marcaida, M.J, Kilchmann, F, Schick, T, Reymond, J.L.
登録日2015-05-15
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening.
J.Med.Chem., 59, 2016
6Z26
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BU of 6z26 by Molmil
Structure of the Danio rerio SAS-6 coiled-coil domain
分子名称: Spindle assembly abnormal protein 6 homolog
著者Kantsadi, A.L, Vakonakis, I.
登録日2020-05-15
公開日2021-05-26
最終更新日2022-05-18
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel.
Structure, 30, 2022
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