Search by PDB author

Pyrazole Carboxylic Acid Inhibitors of KEAP1:NRF2 interaction
分子名称:	5-[(1~{R},2~{R})-2-(1-methyl-1,2,3-triazol-4-yl)cyclopropyl]-1-[3-[3-[(2~{R})-2-propylpiperidin-1-yl]carbonylphenyl]phenyl]pyrazole-4-carboxylic acid, CHLORIDE ION, Kelch-like ECH-associated protein 1, ...
著者	Davies, T.G.
登録日	2021-07-14
公開日	2021-11-17
最終更新日	2024-06-19
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Fragment-Guided Discovery of Pyrazole Carboxylic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2 Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction. J.Med.Chem., 64, 2021

Pyrazole Carboxylic Acid Inhibitors of KEAP1:NRF2 interaction
分子名称:	5-cyclopropyl-1-[3-[2-fluoranyl-3-[(2~{R})-2-propylpiperidin-1-yl]carbonyl-phenyl]phenyl]pyrazole-4-carboxylic acid, CHLORIDE ION, Kelch-like ECH-associated protein 1
著者	Davies, T.G.
登録日	2021-07-14
公開日	2021-11-17
最終更新日	2024-06-19
実験手法	X-RAY DIFFRACTION (1.79 Å)
主引用文献	Fragment-Guided Discovery of Pyrazole Carboxylic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2 Related Factor 2 (KEAP1:NRF2) Protein-Protein Interaction. J.Med.Chem., 64, 2021