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9H6C
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BU of 9h6c by Molmil
Crystal structure of the E. coli F-plasmid VapBC toxin-antitoxin complex (VapB T3N)
分子名称: Antitoxin, tRNA(fMet)-specific endonuclease VapC
著者Hollingshead, S, McVicker, G, Nielsen, M.R, Zhang, Y, Pilla, G, Jones, R.A, Thomas, J.C, Johansen, S.E.H, Exley, R.M, Brodersen, D.E, Tang, C.M.
登録日2024-10-24
公開日2024-12-18
最終更新日2025-02-12
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Shared mechanisms of enhanced plasmid maintenance and antibiotic tolerance mediated by the VapBC toxin:antitoxin system.
Mbio, 16, 2025
9H6D
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BU of 9h6d by Molmil
Crystal structure of the E. coli F-plasmid VapBC toxin-antitoxin complex (VapB V5E)
分子名称: Antitoxin, tRNA(fMet)-specific endonuclease VapC
著者Hollingshead, S, McVicker, G, Nielsen, M.R, Zhang, Y, Pilla, G, Jones, R.A, Thomas, J.C, Johansen, S.E.H, Exley, R.M, Brodersen, D.E, Tang, C.M.
登録日2024-10-24
公開日2024-12-18
最終更新日2025-02-12
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Shared mechanisms of enhanced plasmid maintenance and antibiotic tolerance mediated by the VapBC toxin:antitoxin system.
Mbio, 16, 2025
9H6B
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BU of 9h6b by Molmil
Crystal structure of the E. coli F-plasmid VapBC toxin-antitoxin complex (VapB T3N, A13P, L16R)
分子名称: Antitoxin, tRNA(fMet)-specific endonuclease VapC
著者Hollingshead, S, McVicker, G, Nielsen, M.R, Zhang, Y, Pilla, G, Jones, R.A, Thomas, J.C, Johansen, S.E.H, Exley, R.M, Brodersen, D.E, Tang, C.M.
登録日2024-10-24
公開日2024-12-18
最終更新日2025-02-12
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Shared mechanisms of enhanced plasmid maintenance and antibiotic tolerance mediated by the VapBC toxin:antitoxin system.
Mbio, 16, 2025
3TND
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BU of 3tnd by Molmil
Crystal structure of Shigella flexneri VapBC toxin-antitoxin complex
分子名称: Antitoxin VapB, SODIUM ION, SULFATE ION, ...
著者Dienemann, C, Boggild, A, Winther, K.S, Gerdes, K, Brodersen, D.E.
登録日2011-09-01
公開日2011-11-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of the VapBC Toxin-Antitoxin Complex from Shigella flexneri Reveals a Hetero-Octameric DNA-Binding Assembly.
J.Mol.Biol., 414, 2011
6THH
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BU of 6thh by Molmil
Crystal structure of type I-D CRISPR-Cas nuclease Cas10d in complex with the SIRV3 AcrID1 (gp02) anti-CRISPR protein
分子名称: CRISPR-associated protein, CscA, PHOSPHATE ION, ...
著者Manav, M.C, Brodersen, D.E.
登録日2019-11-20
公開日2020-10-28
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.48 Å)
主引用文献Structural basis for inhibition of an archaeal CRISPR-Cas type I-D large subunit by an anti-CRISPR protein.
Nat Commun, 11, 2020
7QOC
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BU of 7qoc by Molmil
Se-Met derivative structure of a small alarmone hydrolase (RelH) from Corynebacterium glutamicum
分子名称: Guanosine polyphosphate pyrophosphohydrolases/synthetases, MAGNESIUM ION
著者Bisiak, F, Brodersen, D.E, Chrenkova, A.
登録日2021-12-23
公開日2022-07-13
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural variations between small alarmone hydrolase dimers support different modes of regulation of the stringent response.
J.Biol.Chem., 298, 2022
6EXP
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BU of 6exp by Molmil
Crystal structure of the SIRV3 AcrID1 (gp02) anti-CRISPR protein
分子名称: SIRV3 AcrID1 (gp02) anti-CRISPR protein
著者He, F, Bhoobalan-Chitty, Y, Van, L.B, Kjeldsen, A.L, Dedola, M, Makarova, K.S, Koonin, E.V, Brodersen, D.E, Peng, X.
登録日2017-11-08
公開日2018-01-31
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Anti-CRISPR proteins encoded by archaeal lytic viruses inhibit subtype I-D immunity.
Nat Microbiol, 3, 2018
6GFM
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BU of 6gfm by Molmil
Crystal structure of the Escherichia coli nucleosidase PpnN (pppGpp-form)
分子名称: Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase, guanosine 5'-(tetrahydrogen triphosphate) 3'-(trihydrogen diphosphate)
著者Zhang, Y, Baerentsen, R.L, Gerdes, K, Brodersen, D.E.
登録日2018-05-01
公開日2019-04-24
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch.
Mol.Cell, 74, 2019
6GFL
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BU of 6gfl by Molmil
Crystal structure of the Escherichia coli nucleosidase PpnN (apo form)
分子名称: Pyrimidine/purine nucleotide 5'-monophosphate nucleosidase
著者Zhang, Y, Baerentsen, R.L, Gerdes, K, Brodersen, D.E.
登録日2018-05-01
公開日2019-04-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献(p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch.
Mol.Cell, 74, 2019
6GW6
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BU of 6gw6 by Molmil
Structure of the Pseudomonas putida RES-Xre toxin-antitoxin complex
分子名称: GLYCEROL, IMIDAZOLE, RES toxin, ...
著者Senissar, M, Brodersen, D.E.
登録日2018-06-22
公開日2018-10-24
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.205 Å)
主引用文献The RES domain toxins of RES-Xre toxin-antitoxin modules induce cell stasis by degrading NAD.
Mol. Microbiol., 111, 2019
6HPC
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BU of 6hpc by Molmil
Crystal structure of the HicB antitoxin from E. coli
分子名称: Antitoxin HicB
著者Manav, M.C, Brodersen, D.E.
登録日2018-09-20
公開日2019-09-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain.
Structure, 27, 2019
6HPB
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BU of 6hpb by Molmil
Crystal structure of the E.coli HicAB toxin-antitoxin complex
分子名称: Antitoxin HicB, SULFATE ION, mRNA interferase toxin HicA
著者Manav, M.C, Brodersen, D.E.
登録日2018-09-20
公開日2019-09-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain.
Structure, 27, 2019
4V4R
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BU of 4v4r by Molmil
Crystal structure of the whole ribosomal complex.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V.
登録日2005-09-30
公開日2014-07-09
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (5.9 Å)
主引用文献Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
4V4S
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BU of 4v4s by Molmil
Crystal structure of the whole ribosomal complex.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Petry, S, Brodersen, D.E, Murphy IV, F.V, Dunham, C.M, Selmer, M, Tarry, M.J, Kelley, A.C, Ramakrishnan, V.
登録日2005-10-12
公開日2014-07-09
最終更新日2024-12-25
実験手法X-RAY DIFFRACTION (6.76 Å)
主引用文献Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon.
Cell(Cambridge,Mass.), 123, 2005
4V7J
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BU of 4v7j by Molmil
Structure of RelE nuclease bound to the 70S ribosome (precleavage state)
分子名称: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
著者Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E.
登録日2009-11-02
公開日2014-07-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell(Cambridge,Mass.), 139, 2009
4V7K
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BU of 4v7k by Molmil
Structure of RelE nuclease bound to the 70S ribosome (postcleavage state)
分子名称: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
著者Neubauer, C, Gao, Y.-G, Andersen, K.R, Dunham, C.M, Kelley, A.C, Hentschel, J, Gerdes, K, Ramakrishnan, V, Brodersen, D.E.
登録日2009-11-02
公開日2014-07-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell(Cambridge,Mass.), 139, 2009
5IQQ
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BU of 5iqq by Molmil
Crystal structure of the human RBM7 RRM domain
分子名称: RNA-binding protein 7
著者Sofos, N, Winkler, M.B.L, Brodersen, D.E.
登録日2016-03-11
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献RRM domain of human RBM7: purification, crystallization and structure determination.
Acta Crystallogr.,Sect.F, 72, 2016
3G10
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BU of 3g10 by Molmil
Structure of S. pombe Pop2p - Mg2+ and Mn2+ bound form
分子名称: CCR4-Not complex subunit Caf1, MAGNESIUM ION, MANGANESE (II) ION
著者Andersen, K.R, Jonstrup, A.T, Van, L.B, Brodersen, D.E.
登録日2009-01-29
公開日2009-03-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.597 Å)
主引用文献The activity and selectivity of fission yeast Pop2p are affected by a high affinity for Zn2+ and Mn2+ in the active site
Rna, 15, 2009
4R71
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BU of 4r71 by Molmil
Structure of the Qbeta holoenzyme complex in the P1211 crystal form
分子名称: 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu, ...
著者Gytz, H, Seweryn, P, Kutlubaeva, Z, Chetverin, A.B, Brodersen, D.E, Knudsen, C.R.
登録日2014-08-26
公開日2015-09-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Structural basis for RNA-genome recognition during bacteriophage Q beta replication.
Nucleic Acids Res., 43, 2015
5K8J
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BU of 5k8j by Molmil
Structure of Caulobacter crescentus VapBC1 (apo form)
分子名称: GLYCEROL, Ribonuclease VapC, VapB family protein
著者Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
登録日2016-05-30
公開日2016-12-28
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
5L6L
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BU of 5l6l by Molmil
Structure of Caulobacter crescentus VapBC1 bound to operator DNA
分子名称: DNA (27-MER), Ribonuclease VapC, VapB family protein
著者Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
登録日2016-05-30
公開日2016-12-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
5L6M
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BU of 5l6m by Molmil
Structure of Caulobacter crescentus VapBC1 (VapB1deltaC:VapC1 form)
分子名称: GLYCEROL, MALONATE ION, Ribonuclease VapC, ...
著者Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E.
登録日2016-05-30
公開日2016-12-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding.
Nucleic Acids Res., 45, 2017
7AB5
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BU of 7ab5 by Molmil
Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT D233Q)
分子名称: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
著者Baerentsen, R.L, Brodersen, D.E.
登録日2020-09-06
公開日2022-01-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
7AB4
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BU of 7ab4 by Molmil
Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT S59A)
分子名称: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
著者Baerentsen, R.L, Brodersen, D.E.
登録日2020-09-06
公開日2022-01-12
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022
7AB3
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BU of 7ab3 by Molmil
Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT S57A)
分子名称: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ...
著者Baerentsen, R.L, Brodersen, D.E.
登録日2020-09-06
公開日2022-01-12
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation
Biorxiv, 2022

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件を2025-07-09に公開中

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