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N-terminal coiled-coil dimer of C.elegans SAS-6, crystal form B
分子名称:	1,2-ETHANEDIOL, IMIDAZOLE, Spindle assembly abnormal protein 6, ...
著者	Erat, M.C, Vakonakis, I.
登録日	2012-08-03
公開日	2013-06-19
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.85 Å)
主引用文献	Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry. Proc.Natl.Acad.Sci.USA, 110, 2013

6Z26

Structure of the Danio rerio SAS-6 coiled-coil domain
分子名称:	Spindle assembly abnormal protein 6 homolog
著者	Kantsadi, A.L, Vakonakis, I.
登録日	2020-05-15
公開日	2021-05-26
最終更新日	2022-05-18
実験手法	X-RAY DIFFRACTION (2.32 Å)
主引用文献	Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel. Structure, 30, 2022

4GFA

N-terminal coiled-coil dimer of C.elegans SAS-6, crystal form A
分子名称:	(4S)-2-METHYL-2,4-PENTANEDIOL, Spindle assembly abnormal protein 6
著者	Erat, M.C, Vakonakis, I.
登録日	2012-08-03
公開日	2013-06-19
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (3.55 Å)
主引用文献	Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry. Proc.Natl.Acad.Sci.USA, 110, 2013

4G79

Structure a C. elegans SAS-6 variant
分子名称:	GLYCEROL, Spindle assembly abnormal protein 6, TETRAETHYLENE GLYCOL
著者	Erat, M.C, Vakonakis, I.
登録日	2012-07-20
公開日	2013-06-19
最終更新日	2017-08-16
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry. Proc.Natl.Acad.Sci.USA, 110, 2013

4GEX

Structure of a stabilised ceSAS-6 dimer, second crystal form
分子名称:	SULFATE ION, Spindle assembly abnormal protein 6
著者	Erat, M.C, Vakonakis, I.
登録日	2012-08-02
公開日	2013-06-19
最終更新日	2013-07-24
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry. Proc.Natl.Acad.Sci.USA, 110, 2013

4GEU

Structure of a stabilised ceSAS-6 dimer
分子名称:	GLYCEROL, Spindle assembly abnormal protein 6, TETRAETHYLENE GLYCOL
著者	Erat, M.C, Vakonakis, I.
登録日	2012-08-02
公開日	2013-06-19
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.65 Å)
主引用文献	Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry. Proc.Natl.Acad.Sci.USA, 110, 2013

7BJI

Crystal structure of the Danio rerio centrosomal protein Cep135 coiled-coil fragment 64-190
分子名称:	1,2-ETHANEDIOL, ACETATE ION, Centrosomal protein of 135 kDa, ...
著者	Li, Q, Hatzopoulos, G, Iller, O, Vakonakis, I.
登録日	2021-01-14
公開日	2021-01-27
最終更新日	2024-05-15
実験手法	X-RAY DIFFRACTION (2.58 Å)
主引用文献	Crystal structure of the Danio rerio centrosomal protein Cep135 coiled-coil fragment 64-190 To Be Published

7OOE

Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z321318226
分子名称:	AMP PHOSPHORAMIDATE, CHLORIDE ION, GLYCEROL, ...
著者	Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I.
登録日	2021-05-27
公開日	2021-06-02
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.369 Å)
主引用文献	Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published

7OOH

Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818
分子名称:	4-IODOPYRAZOLE, AMP PHOSPHORAMIDATE, CHLORIDE ION, ...
著者	Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I.
登録日	2021-05-27
公開日	2021-06-09
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.36 Å)
主引用文献	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 To Be Published

7OOG

Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023823
分子名称:	4-bromanylpyridin-2-amine, AMP PHOSPHORAMIDATE, CHLORIDE ION, ...
著者	Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I.
登録日	2021-05-27
公開日	2021-06-02
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.42 Å)
主引用文献	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023823 To Be Published

7P31

Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818
分子名称:	4-IODOPYRAZOLE, AMP PHOSPHORAMIDATE, CHLORIDE ION, ...
著者	Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I.
登録日	2021-07-06
公開日	2021-07-14
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.36 Å)
主引用文献	Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with small molecule ligands To Be Published

1M2E

Solution structure of the N-terminal domain of Synechococcus elongatus KaiA (KaiA135N); Average minimized structure.
分子名称:	KaiA
著者	Williams, S.B, Vakonakis, I, Golden, S.S, LiWang, A.C.
登録日	2002-06-23
公開日	2002-11-13
最終更新日	2024-05-22
実験手法	SOLUTION NMR
主引用文献	Structure and Function from the Circadian Clock Protein KaiA of Synechococcus elongatus: A potential Clock Input Mechanism Proc.Natl.Acad.Sci.USA, 99, 2002

1M2F

Solution structure of the N-terminal domain of Synechococcus elongatus KaiA (KaiA135N); Family of 25 structures
分子名称:	KaiA
著者	Williams, S.B, Vakonakis, I, Golden, S.S, LiWang, A.C.
登録日	2002-06-23
公開日	2002-11-13
最終更新日	2024-05-22
実験手法	SOLUTION NMR
主引用文献	Structure and Function from the Circadian Clock Protein KaiA of Synechococcus elongatus: A potential Clock Input Mechanism Proc.Natl.Acad.Sci.USA, 99, 2002

4TS6

Crystal structure of the RIM C2A domain from Drosophila.
分子名称:	GLYCEROL, Rab3 interacting molecule variant 2
著者	Hatzopoulos, G.N, Shiroma, J, Vakonakis, I.
登録日	2014-06-18
公開日	2015-07-01
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (1.92 Å)
主引用文献	Crystal structure of the RIM C2A domain from Drosophila. To Be Published

6SY0

Structure of the Plasmodium falciparum SIP2 DNA-binding AP2 tandem repeat in complex with two SPE2 half-sites
分子名称:	DNA (5'-D(GPGPTPGPCPAPCPCPTPAPGPGPTPGPCPAPCPC)-3'), Transcription factor with AP2 domain(S)
著者	Reiter, D, Kantsadi, A, Vakonakis, I.
登録日	2019-09-26
公開日	2020-10-07
実験手法	X-RAY DIFFRACTION (3.102 Å)
主引用文献	Structural and functional analysis of the Plasmodium falciparum SIP2 DNA binding domain To Be Published

7NQZ

Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z1827898537
分子名称:	(3S)-N-benzylpyrrolidin-3-amine, AMP PHOSPHORAMIDATE, CHLORIDE ION, ...
著者	Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I.
登録日	2021-03-02
公開日	2021-03-10
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.319 Å)
主引用文献	Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published

7NQR

Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z287256168
分子名称:	(S)-N-(1-cyclopropylethyl)-6-methylpicolinamide, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, AMP PHOSPHORAMIDATE, ...
著者	Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I.
登録日	2021-03-02
公開日	2021-03-10
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.22 Å)
主引用文献	Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published

7NQU

Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z396380540
分子名称:	AMP PHOSPHORAMIDATE, CHLORIDE ION, GLYCEROL, ...
著者	Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I.
登録日	2021-03-02
公開日	2021-03-10
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.13 Å)
主引用文献	Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published

7NQS

Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z1203107138
分子名称:	1-ethyl-N-[(4-fluorophenyl)methyl]-1H-pyrazole-4-carboxamide, AMP PHOSPHORAMIDATE, GLYCEROL, ...
著者	Mohamad, N, O'Donoghue, A, Kantsadi, A.L, Vakonakis, I.
登録日	2021-03-02
公開日	2021-03-17
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (2.56 Å)
主引用文献	Structures of P. falciparum Hsp70-x nucleotide binding domain with small molecule ligands To Be Published

1R8J

Crystal Structure of Circadian Clock Protein KaiA from Synechococcus elongatus
分子名称:	KaiA
著者	Ye, S, Vakonakis, I, Sacchettini, J.C, LiWang, A.C.
登録日	2003-10-26
公開日	2004-06-01
最終更新日	2023-08-23
実験手法	X-RAY DIFFRACTION (2.03 Å)
主引用文献	Crystal structure of circadian clock protein KaiA from Synechococcus elongatus J.Biol.Chem., 279, 2004

4LD1

Structural analysis of the microcephaly protein CPAP G-box domain suggests a role in centriole elongation.
分子名称:	(4S)-2-METHYL-2,4-PENTANEDIOL, NITRATE ION, TETRAETHYLENE GLYCOL, ...
著者	Hatzopoulos, G.N, Vakonakis, I.
登録日	2013-06-24
公開日	2013-09-04
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.44 Å)
主引用文献	Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture. Structure, 21, 2013

4LD3

Structural analysis of the microcephaly protein CPAP G-box domain suggests a role in centriole elongation.
分子名称:	GLYCEROL, ISOPROPYL ALCOHOL, SCL-interrupting locus protein homolog, ...
著者	Hatzopoulos, G.N, Vakonakis, I.
登録日	2013-06-24
公開日	2013-09-04
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.44 Å)
主引用文献	Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture. Structure, 21, 2013

4LZF

A novel domain in the microcephaly protein CPAP suggests a role in centriole architecture
分子名称:	(4S)-2-METHYL-2,4-PENTANEDIOL, Centrosomal P4.1-associated protein, SCL-interrupting locus protein homolog, ...
著者	Hatzopoulos, G.N, Erat, M.C, Cutts, E, Rogala, K, Slatter, L, Stansfeld, P.J, Vakonakis, I.
登録日	2013-07-31
公開日	2013-09-11
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (1.72 Å)
主引用文献	Structural analysis of the G-box domain of the microcephaly protein CPAP suggests a role in centriole architecture. Structure, 21, 2013

4JLE

Structure of the P. falciparum PFI1780w PHIST domain
分子名称:	ACETATE ION, CHLORIDE ION, PHIST
著者	Slater, L, Vakonakis, I.
登録日	2013-03-12
公開日	2014-04-16
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.35 Å)
主引用文献	A Plasmodium falciparum PHIST protein binds the virulence factor PfEMP1 and comigrates to knobs on the host cell surface. Faseb J., 28, 2014

6YRL

Structure of the Chlamydomonas reinhardtii SAS-6 coiled-coil domain, C2 crystal form
分子名称:	Centriole protein
著者	Kantsadi, A.L, Vakonakis, I.
登録日	2020-04-20
公開日	2021-05-12
最終更新日	2022-03-16
実験手法	X-RAY DIFFRACTION (2.343 Å)
主引用文献	Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel. Structure, 2022

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