8H8X
 
 | | Cryo-EM structure of HACE1 monomer | | 分子名称: | E3 ubiquitin-protein ligase HACE1 | | 著者 | Singh, S, Machida, S, Tulsian, N.K, Choong, Y.K, Ng, J, Shanker, S, Yaochen, L.D, Shi, J, Sivaraman, J. | | 登録日 | 2022-10-24 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (3.92 Å) | | 主引用文献 | Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization.
Adv Sci, 10, 2023
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8HAE
 | | Cryo-EM structure of HACE1 dimer | | 分子名称: | E3 ubiquitin-protein ligase HACE1 | | 著者 | Singh, S, Machida, S, Tulsian, N.K, Choong, Y.K, Ng, J, Shanker, S, Yaochen, L.D, Shi, J, Sivaraman, J, Machida, S. | | 登録日 | 2022-10-26 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (4.55 Å) | | 主引用文献 | Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization.
Adv Sci, 10, 2023
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5CB2
 | | the structure of candida albicans Sey1p in complex with GMPPNP | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein SEY1 | | 著者 | Yan, L, Sun, S, Wang, W, Shi, J, Hu, X, Wang, S, Rao, Z, Hu, J, Lou, Z. | | 登録日 | 2015-06-30 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion
J.Cell Biol., 210, 2015
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5K79
 | | Structure and anti-HIV activity of CYT-CVNH, a new cyanovirin-n homolog | | 分子名称: | 1,2-ETHANEDIOL, Cyanovirin-N domain protein, DI(HYDROXYETHYL)ETHER | | 著者 | Matei, E, Basu, R, Furey, W, Shi, J, Calnan, C, Aiken, C, Gronenborn, A.M. | | 登録日 | 2016-05-25 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure and Glycan Binding of a New Cyanovirin-N Homolog.
J.Biol.Chem., 291, 2016
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6IDK
 | | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 5.0 (Class I particle) | | 分子名称: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | | 著者 | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | | 登録日 | 2018-09-10 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (25 Å) | | 主引用文献 | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Structure, 27, 2019
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6IDI
 | | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 8.0. | | 分子名称: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | | 著者 | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | | 登録日 | 2018-09-10 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (12 Å) | | 主引用文献 | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Structure, 27, 2019
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6IDL
 | | Cryo-EM structure of Immature Dengue virus serotype 3 in complex with human antibody 1H10 Fab at pH 5.0 (Class II particle) | | 分子名称: | Envelope protein, Fab 1H10 heavy chain (V-region), Fab 1H10 light chain (V-region), ... | | 著者 | Wirawan, M, Fibriansah, G, Ng, T.S, Zhang, Q, Kostyuchenko, V.A, Shi, J, Lok, S.M. | | 登録日 | 2018-09-10 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (25 Å) | | 主引用文献 | Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody.
Structure, 27, 2019
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1J4E
 | | FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE COVALENTLY BOUND TO THE SUBSTRATE DIHYDROXYACETONE PHOSPHATE | | 分子名称: | 1,3-DIHYDROXYACETONEPHOSPHATE, FRUCTOSE-BISPHOSPHATE ALDOLASE A | | 著者 | Choi, K.H, Shi, J, Hopkins, C.E, Tolan, D.R, Allen, K.N. | | 登録日 | 2001-09-19 | | 公開日 | 2002-02-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Snapshots of catalysis: the structure of fructose-1,6-(bis)phosphate aldolase covalently bound to the substrate dihydroxyacetone phosphate.
Biochemistry, 40, 2001
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1JZW
 | | Arsenate Reductase + Sodium Arsenate From E. coli | | 分子名称: | ARSENATE REDUCTASE, CESIUM ION, SULFATE ION, ... | | 著者 | Martin, P, DeMel, S, Shi, J, Gladysheva, T, Gatti, D.L, Rosen, B.P, Edwards, B.F. | | 登録日 | 2001-09-17 | | 公開日 | 2001-11-28 | | 最終更新日 | 2018-04-04 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Insights into the structure, solvation, and mechanism of ArsC arsenate reductase, a novel arsenic detoxification enzyme.
Structure, 9, 2001
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4GJT
 | | complex structure of nectin-4 bound to MV-H | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin glycoprotein, Poliovirus receptor-related protein 4 | | 著者 | Zhang, X, Lu, G, Qi, J, Li, Y, He, Y, Xu, X, Shi, J, Zhang, C, Yan, J, Gao, G.F. | | 登録日 | 2012-08-10 | | 公開日 | 2012-10-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.1001 Å) | | 主引用文献 | Structure of measles virus hemagglutinin bound to its epithelial receptor nectin-4
Nat.Struct.Mol.Biol., 20, 2013
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1TM9
 | | NMR Structure of gene target number gi3844938 from Mycoplasma genitalium: Berkeley Structural Genomics Center | | 分子名称: | Hypothetical protein MG354 | | 著者 | Pelton, J.G, Shi, J, Yokota, H, Kim, R, Wemmer, D.E, Berkeley Structural Genomics Center (BSGC) | | 登録日 | 2004-06-10 | | 公開日 | 2004-08-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structure of Gene Target gi3844938 from Mycoplasma genitalium
To be Published
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2QDY
 | | Crystal Structure of Fe-type NHase from Rhodococcus erythropolis AJ270 | | 分子名称: | 2-METHYLPROPAN-1-AMINE, CHLORIDE ION, FE (III) ION, ... | | 著者 | Song, L, Shi, J, Xue, Z, Wang, M.-X, Qian, S. | | 登録日 | 2007-06-22 | | 公開日 | 2008-05-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | High resolution X-ray molecular structure of the nitrile hydratase from Rhodococcus erythropolis AJ270 reveals posttranslational oxidation of two cysteines into sulfinic acids and a novel biocatalytic nitrile hydration mechanism
Biochem.Biophys.Res.Commun., 362, 2007
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5HDE
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6MS7
 | | Peroxisome proliferator-activated receptor gamma ligand binding domain in complex with a novel selective PPAR-gamma modulator VSP-77 | | 分子名称: | PGC1 LXXLL motif, Peroxisome proliferator-activated receptor gamma, {[(1S)-1-(4-chlorophenyl)octyl]oxy}acetic acid | | 著者 | Yi, W, Jiang, H, Zhou, X.E, Shi, J, Zhao, G, Zhang, X, Sun, Y, Suino-Powell, K, Li, J, Li, J, Melcher, K, Xu, H.E. | | 登録日 | 2018-10-16 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Identification and structural insight of an effective PPAR gamma modulator with improved therapeutic index for anti-diabetic drug discovery.
Chem Sci, 11, 2020
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5H37
 | | Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C10 IgG heavy chain variable region, C10 IgG light chain variable region, ... | | 著者 | Zhang, S, Kostyuchenko, V, Ng, T.-S, Lim, X.-N, Ooi, J.S.G, Lambert, S, Tan, T.Y, Widman, D, Shi, J, Baric, R.S, Lok, S.-M. | | 登録日 | 2016-10-20 | | 公開日 | 2016-11-30 | | 最終更新日 | 2022-03-23 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Neutralization mechanism of a highly potent antibody against Zika virus
Nat Commun, 7, 2016
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3NMQ
 | | Hsp90b N-terminal domain in complex with EC44, a pyrrolo-pyrimidine methoxypyridine inhibitor | | 分子名称: | 5-{2-amino-4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-methylpent-4-yn-2 -ol, Heat shock protein HSP 90-beta | | 著者 | Arndt, J.W, Yun, T.J, Harning, E.K, Giza, K, Rabah, D, Li, P, Luchetti, D, Shi, J, Manning, A, Kehry, M.R. | | 登録日 | 2010-06-22 | | 公開日 | 2010-12-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | EC144, a Synthetic Inhibitor of Heat Shock Protein 90, Blocks Innate and Adaptive Immune Responses in Models of Inflammation and Autoimmunity.
J.Immunol., 186, 2011
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6LK0
 | | Crystal structure of human wild type TRIP13 | | 分子名称: | Pachytene checkpoint protein 2 homolog | | 著者 | Wang, Y, Huang, J, Li, B, Xue, H, Tricot, G, Hu, L, Xu, Z, Sun, X, Chang, S, Gao, L, Tao, Y, Xu, H, Xie, Y, Xiao, W, Yu, D, Kong, Y, Chen, G, Sun, X, Lian, F, Zhang, N, Wu, X, Mao, Z, Zhan, F, Zhu, W, Shi, J. | | 登録日 | 2019-12-17 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Cancer Res., 80, 2020
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6LNU
 | | Cryo-EM structure of immature Zika virus | | 分子名称: | Genome polyprotein | | 著者 | Tan, T.Y, Fibriansah, G, Kostyuchenko, V.A, Ng, T.S, Lim, X.X, Lim, X.N, Shi, J, Morais, M.C, Corti, D, Lok, S.M. | | 登録日 | 2020-01-02 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Capsid protein structure in Zika virus reveals the flavivirus assembly process.
Nat Commun, 11, 2020
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6LNT
 | | Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab | | 分子名称: | Envelope protein, Fab DV62.5 heavy-chain variable region, Fab DV62.5 light-chain variable region, ... | | 著者 | Tan, T.Y, Fibriansah, G, Kostyuchenko, V.A, Ng, T.S, Lim, X.X, Lim, X.N, Shi, J, Morais, M.C, Corti, D, Lok, S.M. | | 登録日 | 2020-01-02 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | Capsid protein structure in Zika virus reveals the flavivirus assembly process.
Nat Commun, 11, 2020
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5TWO
 | | Peroxisome proliferator-activated receptor gamma ligand binding domain in complex with a novel selectively PPAR gamma-modulating ligand VSP-51 | | 分子名称: | N-benzyl-1-[(4-chloro-3-fluorophenyl)methyl]-1H-indole-5-carboxamide, PRO-SER-LEU-LEU-LYS-LYS-LEU-LEU-LEU-ALA-PRO, Peroxisome proliferator-activated receptor gamma | | 著者 | Yi, W, Shi, J, Zhao, G, Zhou, X.E, Suino-Powell, K, Melcher, K, Xu, H.E. | | 登録日 | 2016-11-14 | | 公開日 | 2017-02-08 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.927 Å) | | 主引用文献 | Identification of a novel selective PPAR gamma ligand with a unique binding mode and improved therapeutic profile in vitro.
Sci Rep, 7, 2017
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5WSO
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5X8R
 | | Structure of the 30S small subunit of chloroplast ribosome from spinach | | 分子名称: | 16S rRNA, 30S ribosomal protein S1, chloroplastic, ... | | 著者 | Ahmed, T, Shi, J, Bhushan, S. | | 登録日 | 2017-03-03 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation
Nucleic Acids Res., 45, 2017
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5X8P
 | | Structure of the 70S chloroplast ribosome from spinach | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | | 著者 | Ahmed, T, Shi, J, Bhushan, S. | | 登録日 | 2017-03-03 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation
Nucleic Acids Res., 45, 2017
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5X8T
 | | Structure of the 50S large subunit of chloroplast ribosome from spinach | | 分子名称: | 23S rRNA, 4.8S rRNA, 50S ribosomal protein L13, ... | | 著者 | Ahmed, T, Shi, J, Bhushan, S. | | 登録日 | 2017-03-03 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation
Nucleic Acids Res., 45, 2017
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5ZEU
 | | M. smegmatis P/P state 30S ribosomal subunit | | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | 著者 | Mishra, S, Ahmed, T, Tyagi, A, Shi, J, Bhushan, S. | | 登録日 | 2018-02-28 | | 公開日 | 2018-09-26 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA.
Sci Rep, 8, 2018
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