5YYX
 
 | | Crystal Structure of the MEK1 FHA domain | | 分子名称: | Meiosis-specific serine/threonine-protein kinase MEK1 | | 著者 | Xie, C, Li, F, Jiang, Y, Wu, J, Shi, Y. | | 登録日 | 2017-12-11 | | 公開日 | 2018-10-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.684 Å) | | 主引用文献 | Structural insights into the recognition of phosphorylated Hop1 by Mek1
Acta Crystallogr D Struct Biol, 74, 2018
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5ZNC
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5ZNI
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6ACU
 | | The structure of CVA10 virus mature virion | | 分子名称: | SPHINGOSINE, VP1, VP2, ... | | 著者 | Cui, Y.X, Zheng, Q.B, Zhu, R, Xu, L.F, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | 登録日 | 2018-07-27 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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6ACW
 | | The structure of CVA10 virus procapsid particle | | 分子名称: | VP0, VP1, VP3 | | 著者 | Zhu, R, Xu, L.F, Zheng, Q.B, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | 登録日 | 2018-07-27 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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6AJ2
 | | The structure of ICAM-5 triggered Enterovirus D68 virus A-particle | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 | | 著者 | Zheng, Q.B, Zhu, R, Xu, L.F, He, M.Z, Yan, X.D, Cheng, T, Li, S.W. | | 登録日 | 2018-08-26 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
Nat Microbiol, 4, 2019
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6AJ0
 | | The structure of Enterovirus D68 mature virion | | 分子名称: | Capsid protein VP3, Capsid protein VP4, Viral protein 1, ... | | 著者 | Zheng, Q.B, Zhu, R, Xu, L.F, He, M.Z, Yan, X.D, Cheng, T, Li, S.W. | | 登録日 | 2018-08-25 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Atomic structures of enterovirus D68 in complex with two monoclonal antibodies define distinct mechanisms of viral neutralization
Nat Microbiol, 4, 2019
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6AD1
 | | The structure of CVA10 procapsid from its complex with Fab 2G8 | | 分子名称: | VP0, VP1, VP3 | | 著者 | Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | 登録日 | 2018-07-28 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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7WHZ
 | | SARS-CoV-2 spike protein in complex with three human neutralizing antibodies | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ... | | 著者 | Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S. | | 登録日 | 2022-01-01 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron.
Cell Rep, 39, 2022
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6AD0
 | | The structure of CVA10 mature virion in complex with Fab 2G8 | | 分子名称: | SPHINGOSINE, VH of Fab 2G8, VL of Fab 2G8, ... | | 著者 | Zhu, R, Zheng, Q.B, Xu, L.F, Cui, Y.X, Li, S.W, Yan, X.D, Zhou, Z.H, Cheng, T. | | 登録日 | 2018-07-28 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Discovery and structural characterization of a therapeutic antibody against coxsackievirus A10.
Sci Adv, 4, 2018
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7WI0
 | | SARS-CoV-2 Omicron variant spike in complex with three human neutralizing antibodies | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c1437_light_IGLV1-40_IGLJ1, IG c934_light_IGKV1-5_IGKJ1, ... | | 著者 | Zheng, Q, Li, S, Sun, H, Zheng, Z, Wang, S. | | 登録日 | 2022-01-01 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | | 主引用文献 | Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron.
Cell Rep, 39, 2022
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1PHT
 | | PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT SH3 DOMAIN, RESIDUES 1-85 | | 分子名称: | PHOSPHATIDYLINOSITOL 3-KINASE P85-ALPHA SUBUNIT | | 著者 | Liang, J, Chen, J.K, Schreiber, S.L, Clardy, J. | | 登録日 | 1995-08-17 | | 公開日 | 1995-12-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of P13K SH3 domain at 20 angstroms resolution.
J.Mol.Biol., 257, 1996
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7DNH
 | | 2-fold subparticles refinement of human papillomavirus type 58 pseudovirus in complexed with the Fab fragment of 2H3 | | 分子名称: | Major capsid protein L1, The heavy chain of 2H3 Fab fragment, The light chain of 2H3 Fab fragment | | 著者 | He, M.Z, Chi, X, Zha, Z.H, Zheng, Q.B, Gu, Y, Li, S.W, Xia, N.S. | | 登録日 | 2020-12-09 | | 公開日 | 2020-12-30 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | Structural basis for the shared neutralization mechanism of three classes of human papillomavirus type 58 antibodies with disparate modes of binding.
J.Virol., 95, 2021
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7DNK
 | | 2-fold subparticles refinement of human papillomavirus type 58 pseudovirus in complexed with the Fab fragment of 5G9 | | 分子名称: | Major capsid protein L1, The heavy chain of 5G9 Fab fragment, The light chain of 5G9 Fab fragment | | 著者 | He, M.Z, Chi, X, Zha, Z.H, Zheng, Q.B, Gu, Y, Li, S.W, Xia, N.S. | | 登録日 | 2020-12-09 | | 公開日 | 2020-12-30 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (6.41 Å) | | 主引用文献 | Structural basis for the shared neutralization mechanism of three classes of human papillomavirus type 58 antibodies with disparate modes of binding.
J.Virol., 95, 2021
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7DNL
 | | 2-fold subparticles refinement of human papillomavirus type 58 pseudovirus in complexed with the Fab fragment of A4B4 | | 分子名称: | Major capsid protein L1, The heavy chain of 2H3 Fab fragment, The light chain of A4B4 Fab fragment | | 著者 | He, M.Z, Chi, X, Zha, Z.H, Zheng, Q.B, Gu, Y, Li, S.W, Xia, N.S. | | 登録日 | 2020-12-09 | | 公開日 | 2020-12-30 | | 最終更新日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (4.19 Å) | | 主引用文献 | Structural basis for the shared neutralization mechanism of three classes of human papillomavirus type 58 antibodies with disparate modes of binding.
J.Virol., 95, 2021
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7WKX
 | | IL-17A in complex with the humanized antibody HB0017 | | 分子名称: | ACETIC ACID, Heavy chain of HB0017 Fab, Interleukin-17A, ... | | 著者 | Xu, J, Zhu, X, He, Y. | | 登録日 | 2022-01-12 | | 公開日 | 2022-03-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Structural and functional insights into a novel pre-clinical-stage antibody targeting IL-17A for treatment of autoimmune diseases.
Int.J.Biol.Macromol., 202, 2022
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7FJ3
 | | Cryo-EM structure of PRV A-capid | | 分子名称: | Major capsid protein, Small capsomere-interacting protein, Triplex capsid protein 1, ... | | 著者 | Zheng, Q, Li, S, Zha, Z, Sun, H. | | 登録日 | 2021-08-02 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (4.53 Å) | | 主引用文献 | Structures of pseudorabies virus capsids.
Nat Commun, 13, 2022
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7FJ1
 | | Cryo-EM structure of pseudorabies virus C-capsid | | 分子名称: | Capsid vertex component 1, DNA packaging tegument protein UL25, Major capsid protein, ... | | 著者 | Zheng, Q, Li, S, Zha, Z, Sun, H. | | 登録日 | 2021-08-02 | | 公開日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (4.43 Å) | | 主引用文献 | Structures of pseudorabies virus capsids.
Nat Commun, 13, 2022
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7YHK
 | | Cryo-EM structure of the HA trimer of A/Beijing/262/1995(H1N1) in complex with neutralizing antibody 12H5 | | 分子名称: | 12H5 heavy chain, 12H5 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zheng, Q, Li, S, Li, T, Xue, W, Sun, H. | | 登録日 | 2022-07-13 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses.
Nat Commun, 13, 2022
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6ICV
 | | Structure of SETD3 bound to SAH and unmodified actin | | 分子名称: | Actin, cytoplasmic 1, Histone-lysine N-methyltransferase setd3, ... | | 著者 | Guo, Q, Liao, S, Xu, C, Structural Genomics Consortium (SGC) | | 登録日 | 2018-09-07 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural insights into SETD3-mediated histidine methylation on beta-actin.
Elife, 8, 2019
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6ICT
 | | Structure of SETD3 bound to SAH and methylated actin | | 分子名称: | Actin, cytoplasmic 1, Histone-lysine N-methyltransferase setd3, ... | | 著者 | Guo, Q, Liao, S, Xu, C, Structural Genomics Consortium (SGC) | | 登録日 | 2018-09-07 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | | 主引用文献 | Structural insights into SETD3-mediated histidine methylation on beta-actin.
Elife, 8, 2019
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7YEA
 | | Human O-GlcNAc transferase Dimer | | 分子名称: | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | | 著者 | Gao, H, Lu, P, Liu, Y. | | 登録日 | 2022-07-05 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | ELECTRON MICROSCOPY (3.82 Å) | | 主引用文献 | Cryo-EM structure of human O-GlcNAcylation enzyme pair OGT-OGA complex.
Nat Commun, 14, 2023
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7FAH
 | | Immune complex of head region of CA09 HA and neutralizing antibody 12H5 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Li, T.T, Xue, W.H, Gu, Y, Li, S.W. | | 登録日 | 2021-07-06 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.151 Å) | | 主引用文献 | Identification of a cross-neutralizing antibody that targets the receptor binding site of H1N1 and H5N1 influenza viruses.
Nat Commun, 13, 2022
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7XPR
 | | Crystal structrue of SeMet-MtdL:GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Transglycosylse | | 著者 | Li, F.D, He, C. | | 登録日 | 2022-05-05 | | 公開日 | 2023-03-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures of the NDP-pyranose mutase belonging to glycosyltransferase family 75 reveal residues important for Mn 2+ coordination and substrate binding.
J.Biol.Chem., 299, 2023
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7XPT
 | | Crystal structrue of MtdL:GDP:Mn soaked with GDP-Glc | | 分子名称: | GDP-ALPHA-D-GLUCOSE, MANGANESE (II) ION, Transglycosylse | | 著者 | Li, F.D, He, C. | | 登録日 | 2022-05-05 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of the NDP-pyranose mutase belonging to glycosyltransferase family 75 reveal residues important for Mn 2+ coordination and substrate binding.
J.Biol.Chem., 299, 2023
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