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7XOV
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BU of 7xov by Molmil
Structural insights into human brain gut peptide cholecystokinin receptors
分子名称: 2-[2-[[4-(4-chloranyl-2,5-dimethoxy-phenyl)-5-(2-cyclohexylethyl)-1,3-thiazol-2-yl]carbamoyl]-5,7-dimethyl-indol-1-yl]ethanoic acid, Cholecystokinin receptor type A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Ding, Y, Zhang, H, Liao, Y, Chen, L, Ji, S.
登録日2022-05-01
公開日2022-07-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into human brain-gut peptide cholecystokinin receptors.
Cell Discov, 8, 2022
7XYD
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BU of 7xyd by Molmil
Crystal structure of TMPRSS2 in complex with Nafamostat
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ...
著者Wang, H, Liu, X, Duan, Y, Liu, X, Sun, L, Yang, H.
登録日2022-06-01
公開日2023-12-06
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
7Y0F
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BU of 7y0f by Molmil
Crystal structure of TMPRSS2 in complex with UK-371804
分子名称: 2-[(1-carbamimidamido-4-chloranyl-isoquinolin-7-yl)sulfonylamino]-2-methyl-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H.
登録日2022-06-04
公開日2023-12-06
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
7Y0E
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BU of 7y0e by Molmil
Crystal structure of TMPRSS2 in complex with Camostat
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, CALCIUM ION, ...
著者Wang, H, Duan, Y, Liu, X, Sun, L, Yang, H.
登録日2022-06-04
公開日2023-12-06
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structure-based discovery of dual pathway inhibitors for SARS-CoV-2 entry.
Nat Commun, 14, 2023
4KAM
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BU of 4kam by Molmil
X-ray crystal structure of O-acetylhomoserine sulfhydrylase MetC from Mycobacterium marinum ATCC BAA-535 / M
分子名称: O-acetylhomoserine sulfhydrylase MetC, SULFATE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2013-04-22
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4K3E
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BU of 4k3e by Molmil
Crystal structure of bovine antibody BLV5B8 with ultralong CDR H3
分子名称: BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ...
著者Ekiert, D.C, Wang, F, Wilson, I.A.
登録日2013-04-10
公開日2013-06-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Reshaping antibody diversity.
Cell(Cambridge,Mass.), 153, 2013
6A92
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BU of 6a92 by Molmil
Crystal structure of a cyclase Filc1 from Fischerella sp.
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, TETRAETHYLENE GLYCOL, ...
著者Hu, X.Y, Liu, W.D, Chen, C.C, Guo, R.T.
登録日2018-07-11
公開日2018-12-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement
Angew. Chem. Int. Ed. Engl., 57, 2018
4J1U
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BU of 4j1u by Molmil
Crystal structure of antibody 93F3 unstable variant
分子名称: antibody 93F3 Heavy chain, antibody 93F3 Light chain
著者Wang, F.
登録日2013-02-02
公開日2013-03-13
最終更新日2013-05-22
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4I88
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BU of 4i88 by Molmil
R107G HSP16.5
分子名称: Small heat shock protein HSP16.5
著者Pohl, E, Williamson, I.R, Quinlan, R.A.
登録日2012-12-03
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Changes in the quaternary structure and function of MjHSP16.5 attributable to deletion of the IXI motif and introduction of the substitution, R107G, in the alpha-crystallin domain.
PHILOS.TRANS.R.SOC.LOND.B BIOL.SCI., 368, 2013
4KW5
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BU of 4kw5 by Molmil
M. tuberculosis DprE1 in complex with inhibitor TCA1
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, IMIDAZOLE, ...
著者Batt, S.M, Besra, G.S, Futterer, K.
登録日2013-05-23
公開日2013-07-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.612 Å)
主引用文献Identification of a small molecule with activity against drug-resistant and persistent tuberculosis.
Proc.Natl.Acad.Sci.USA, 110, 2013
6IRA
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BU of 6ira by Molmil
Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 7.8
分子名称: Glutamate receptor ionotropic, NMDA 1, NMDA 2A
著者Zhang, J, Chang, S, Zhang, X, Zhu, S.
登録日2018-11-12
公開日2019-01-16
最終更新日2019-06-05
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors
Cell Rep, 25, 2018
6IV3
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BU of 6iv3 by Molmil
Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation W252A
分子名称: Bestrophin homolog, ZINC ION
著者Kittredge, A, Chen, S, Yang, T.
登録日2018-12-02
公開日2019-11-13
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.515 Å)
主引用文献Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019
2YU2
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BU of 2yu2 by Molmil
Crystal structure of hJHDM1A without a-ketoglutarate
分子名称: FE (II) ION, JmjC domain-containing histone demethylation protein 1A
著者Han, Z.
登録日2007-04-05
公開日2007-04-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for histone demethylation by JHDM1
To be Published
3QDR
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BU of 3qdr by Molmil
Structural characterization of the interaction of colicin A, colicin N, and TolB with the TolAIII translocon
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Colicin-A, Protein tolA
著者Li, C.
登録日2011-01-19
公開日2012-01-25
最終更新日2012-06-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural Evidence That Colicin A Protein Binds to a Novel Binding Site of TolA Protein in Escherichia coli Periplasm.
J.Biol.Chem., 287, 2012
2YU1
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BU of 2yu1 by Molmil
Crystal structure of hJHDM1A complexed with a-ketoglutarate
分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, JmjC domain-containing histone demethylation protein 1A
著者Han, Z.
登録日2007-04-05
公開日2007-04-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for histone demethylation by JHDM1
To be Published
3QHA
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BU of 3qha by Molmil
Crystal structure of a Putative oxidoreductase from Mycobacterium avium 104
分子名称: Putative oxidoreductase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-01-25
公開日2011-02-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
5XVW
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BU of 5xvw by Molmil
Crystal structure of AL2 PAL domain in complex with AtRing1a distal site
分子名称: AtRing1a distal binding site, PHD finger protein ALFIN-LIKE 2
著者Peng, L, Wang, L.L, Huang, Y.
登録日2017-06-28
公開日2018-07-04
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Structural Analysis of the Arabidopsis AL2-PAL and PRC1 Complex Provides Mechanistic Insight into Active-to-Repressive Chromatin State Switch
J. Mol. Biol., 430, 2018
3R7K
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BU of 3r7k by Molmil
Crystal structure of a probable acyl CoA dehydrogenase from Mycobacterium abscessus ATCC 19977 / DSM 44196
分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, POTASSIUM ION, Probable acyl CoA dehydrogenase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-03-22
公開日2011-04-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3R1J
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BU of 3r1j by Molmil
Crystal structure of Alpha-ketoglutarate-dependent taurine dioxygenase from Mycobacterium avium, native form
分子名称: 1,2-ETHANEDIOL, Alpha-ketoglutarate-dependent taurine dioxygenase, CHLORIDE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-03-10
公開日2011-04-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
6IV0
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BU of 6iv0 by Molmil
Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation I180A
分子名称: Bestrophin homolog, ZINC ION
著者Kittredge, A, Chen, S, Yang, T.
登録日2018-12-02
公開日2019-11-13
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019
6IVW
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BU of 6ivw by Molmil
Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation D269A
分子名称: Bestrophin homolog, ZINC ION
著者Kittredge, A, Chen, S, Yang, T.
登録日2018-12-04
公開日2019-11-13
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.72 Å)
主引用文献Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations.
Commun Biol, 2, 2019
3R6H
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BU of 3r6h by Molmil
Crystal structure of an enoyl-CoA hydratase (ECHA3) from Mycobacterium marinum
分子名称: CHLORIDE ION, Enoyl-CoA hydratase, EchA3, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-03-21
公開日2011-06-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
7E53
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BU of 7e53 by Molmil
Crystal structure of sfGFP complexed with the nanobody nb2 at 2.2 Angstron resolution
分子名称: Green fluorescent protein, Green fluorescent protein's nanobody nb2
著者Ding, Y, Zhong, P.Y.
登録日2021-02-16
公開日2021-10-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural insights into two distinct nanobodies recognizing the same epitope of green fluorescent protein.
Biochem.Biophys.Res.Commun., 565, 2021
6IRH
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BU of 6irh by Molmil
Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 6.3, Class III
分子名称: Glutamate receptor ionotropic, NMDA 1, NMDA 2A
著者Zhang, J, Chang, S, Zhang, X, Zhu, S.
登録日2018-11-12
公開日2019-01-16
最終更新日2019-06-05
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors
Cell Rep, 25, 2018
3TDE
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BU of 3tde by Molmil
Crystal structure of S-adenosylmethionine synthetase Rv1392 from Mycobacterium tuberculosis
分子名称: S-adenosylmethionine synthase, SODIUM ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-08-10
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015

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