 | | A1BG9 | | Name: | 4-methyl-2-[(3S)-piperidin-3-yl]-N-(pyridin-2-yl)-1H-imidazole-5-carboxamide | | Formula: | C15 H19 N5 O | | SMILES: | Cc1nc([NH]c1C(=O)Nc1ccccn1)C1CCCNC1 | | InChi: | InChI=1S/C15H19N5O/c1-10-13(15(21)19-12-6-2-3-8-17-12)20-14(18-10)11-5-4-7-16-9-11/h2-3,6,8,11,16H,4-5,7,9H2,1H3,(H,18,20)(H,17,19,21)/t11-/m0/s1 | | Definition date: | 2024-11-11 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | 4-methyl-2-[(3S)-piperidin-3-yl]-N-(pyridin-2-yl)-1H-imidazole-5-carboxamide |
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 | | A1BGQ | | Name: | N-[(2S)-3-[4-(aminomethyl)phenyl]-1-oxo-1-(piperidin-1-yl)propan-2-yl]benzamide | | Formula: | C22 H27 N3 O2 | | SMILES: | O=C(C(Cc1ccc(CN)cc1)NC(=O)c1ccccc1)N1CCCCC1 | | InChi: | InChI=1S/C22H27N3O2/c23-16-18-11-9-17(10-12-18)15-20(22(27)25-13-5-2-6-14-25)24-21(26)19-7-3-1-4-8-19/h1,3-4,7-12,20H,2,5-6,13-16,23H2,(H,24,26)/t20-/m0/s1 | | Definition date: | 2024-11-11 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | N-[(2S)-3-[4-(aminomethyl)phenyl]-1-oxo-1-(piperidin-1-yl)propan-2-yl]benzamide |
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 | | A1BGR | | Name: | N-{3-chloro-5-[(1-hydroxy-2-methylpropan-2-yl)carbamoyl]phenyl}-2-methyl-3-oxo-2,3-dihydro-1,2-oxazole-5-carboxamide | | Formula: | C16 H18 Cl N3 O5 | | SMILES: | O=C(Nc1cc(cc(Cl)c1)C(=O)NC(C)(C)CO)C1=CC(=O)N(C)O1 | | InChi: | InChI=1S/C16H18ClN3O5/c1-16(2,8-21)19-14(23)9-4-10(17)6-11(5-9)18-15(24)12-7-13(22)20(3)25-12/h4-7,21H,8H2,1-3H3,(H,18,24)(H,19,23) | | Definition date: | 2024-11-11 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | N-{3-chloro-5-[(1-hydroxy-2-methylpropan-2-yl)carbamoyl]phenyl}-2-methyl-3-oxo-2,3-dihydro-1,2-oxazole-5-carboxamide |
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 | | A1BGU | | Name: | N-(1-methyl-1H-pyrazol-4-yl)-2-[(propan-2-yl)amino]-1H-1,3-benzimidazole-6-carboxamide | | Formula: | C15 H18 N6 O | | SMILES: | O=C(Nc1cn(C)nc1)c1ccc2nc(NC(C)C)[NH]c2c1 | | InChi: | InChI=1S/C15H18N6O/c1-9(2)17-15-19-12-5-4-10(6-13(12)20-15)14(22)18-11-7-16-21(3)8-11/h4-9H,1-3H3,(H,18,22)(H2,17,19,20) | | Definition date: | 2024-11-11 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | N-(1-methyl-1H-pyrazol-4-yl)-2-[(propan-2-yl)amino]-1H-1,3-benzimidazole-6-carboxamide |
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 | | A1BGV | | Name: | N-(5-carbamoyl-1H-pyrrol-3-yl)-2-[(propan-2-yl)amino]-1H-1,3-benzimidazole-6-carboxamide | | Formula: | C16 H18 N6 O2 | | SMILES: | NC(=O)c1cc(c[NH]1)NC(=O)c1ccc2nc(NC(C)C)[NH]c2c1 | | InChi: | InChI=1S/C16H18N6O2/c1-8(2)19-16-21-11-4-3-9(5-12(11)22-16)15(24)20-10-6-13(14(17)23)18-7-10/h3-8,18H,1-2H3,(H2,17,23)(H,20,24)(H2,19,21,22) | | Definition date: | 2024-11-11 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | N-(5-carbamoyl-1H-pyrrol-3-yl)-2-[(propan-2-yl)amino]-1H-1,3-benzimidazole-6-carboxamide |
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 | | A1BGY | | Name: | 5-cyclopropyl-1,2-dimethyl-N-(3-methylpyridin-4-yl)-1H-pyrrole-3-carboxamide | | Formula: | C16 H19 N3 O | | SMILES: | O=C(Nc1ccncc1C)c1cc(C2CC2)n(C)c1C | | InChi: | InChI=1S/C16H19N3O/c1-10-9-17-7-6-14(10)18-16(20)13-8-15(12-4-5-12)19(3)11(13)2/h6-9,12H,4-5H2,1-3H3,(H,17,18,20) | | Definition date: | 2024-11-11 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | 5-cyclopropyl-1,2-dimethyl-N-(3-methylpyridin-4-yl)-1H-pyrrole-3-carboxamide |
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 | | A1BGZ | | Name: | (2M)-2-[2-(methoxymethyl)pyridin-4-yl]-N-(1-methyl-1H-pyrazol-4-yl)benzamide | | Formula: | C18 H18 N4 O2 | | SMILES: | O=C(Nc1cn(C)nc1)c1ccccc1c1ccnc(COC)c1 | | InChi: | InChI=1S/C18H18N4O2/c1-22-11-15(10-20-22)21-18(23)17-6-4-3-5-16(17)13-7-8-19-14(9-13)12-24-2/h3-11H,12H2,1-2H3,(H,21,23) | | Definition date: | 2024-11-11 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (2M)-2-[2-(methoxymethyl)pyridin-4-yl]-N-(1-methyl-1H-pyrazol-4-yl)benzamide |
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 | | A1BHA | | Name: | 4-methoxy-2-(piperazin-1-yl)-6-{[(pyrimidin-5-yl)oxy]methyl}pyrimidine | | Formula: | C14 H18 N6 O2 | | SMILES: | COc1nc(nc(COc2cncnc2)c1)N1CCNCC1 | | InChi: | InChI=1S/C14H18N6O2/c1-21-13-6-11(9-22-12-7-16-10-17-8-12)18-14(19-13)20-4-2-15-3-5-20/h6-8,10,15H,2-5,9H2,1H3 | | Definition date: | 2024-11-11 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | 4-methoxy-2-(piperazin-1-yl)-6-{[(pyrimidin-5-yl)oxy]methyl}pyrimidine |
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 | | A1BHC | | Name: | 3-chloro-5-[({3-[(dimethylamino)methyl]-4-hydroxyphenyl}methyl)amino]-N-(1-hydroxy-2-methylpropan-2-yl)benzamide | | Formula: | C21 H28 Cl N3 O3 | | SMILES: | Clc1cc(cc(NCc2ccc(O)c(CN(C)C)c2)c1)C(=O)NC(C)(C)CO | | InChi: | InChI=1S/C21H28ClN3O3/c1-21(2,13-26)24-20(28)15-8-17(22)10-18(9-15)23-11-14-5-6-19(27)16(7-14)12-25(3)4/h5-10,23,26-27H,11-13H2,1-4H3,(H,24,28) | | Definition date: | 2024-11-11 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | 3-chloro-5-[({3-[(dimethylamino)methyl]-4-hydroxyphenyl}methyl)amino]-N-(1-hydroxy-2-methylpropan-2-yl)benzamide |
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 | | A1BIV | | Name: | 6-(4-chlorophenyl)-1-methyl-5-[(3S)-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl]-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione | | Formula: | C22 H17 Cl N4 O3 | | SMILES: | Clc1ccc(cc1)c1[NH]c2c(C(=O)NC(=O)N2C)c1C1c2ccccc2N(C)C1=O | | InChi: | InChI=1S/C22H17ClN4O3/c1-26-14-6-4-3-5-13(14)15(21(26)29)16-17-19(27(2)22(30)25-20(17)28)24-18(16)11-7-9-12(23)10-8-11/h3-10,15,24H,1-2H3,(H,25,28,30)/t15-/m0/s1 | | Definition date: | 2024-12-02 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | 6-(4-chlorophenyl)-1-methyl-5-[(3S)-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl]-1H-pyrrolo[2,3-d]pyrimidine-2,4(3H,7H)-dione |
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 | | A1BIW | | Name: | N-[(5R)-1,1-dioxo-2,3,4,5-tetrahydro-1H-1lambda~6~-benzothiepin-5-yl]-2-hydroxyquinoxaline-6-carboxamide | | Formula: | C19 H17 N3 O4 S | | SMILES: | Oc1cnc2cc(ccc2n1)C(=O)NC1CCCS(=O)(=O)c2ccccc21 | | InChi: | InChI=1S/C19H17N3O4S/c23-18-11-20-16-10-12(7-8-15(16)21-18)19(24)22-14-5-3-9-27(25,26)17-6-2-1-4-13(14)17/h1-2,4,6-8,10-11,14H,3,5,9H2,(H,21,23)(H,22,24)/t14-/m1/s1 | | Definition date: | 2024-12-02 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | N-[(5R)-1,1-dioxo-2,3,4,5-tetrahydro-1H-1lambda~6~-benzothiepin-5-yl]-2-hydroxyquinoxaline-6-carboxamide |
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 | | A1BIX | | Name: | (4S)-4-(3-ethoxyphenyl)-3-methyl-1-[(4R)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-b]pyridin-6-one | | Formula: | C20 H19 N7 O2 | | SMILES: | CCOc1cccc(c1)C1CC(=O)Nc2c1c(C)nn2c1ccc2nncn2n1 | | InChi: | InChI=1S/C20H19N7O2/c1-3-29-14-6-4-5-13(9-14)15-10-18(28)22-20-19(15)12(2)24-27(20)17-8-7-16-23-21-11-26(16)25-17/h4-9,11,15H,3,10H2,1-2H3,(H,22,28)/t15-/m0/s1 | | Definition date: | 2024-12-02 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (4S)-4-(3-ethoxyphenyl)-3-methyl-1-[(4R)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-b]pyridin-6-one |
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 | | A1BLQ | | Name: | (2P)-2-(4-{[(3R)-1-methylpiperidin-3-yl]amino}-5,6,7,8-tetrahydrophthalazin-1-yl)-5-(trifluoromethyl)phenol | | Formula: | C21 H25 F3 N4 O | | SMILES: | CN1CCCC(Nc2nnc(c3ccc(cc3O)C(F)(F)F)c3CCCCc23)C1 | | InChi: | InChI=1S/C21H25F3N4O/c1-28-10-4-5-14(12-28)25-20-16-7-3-2-6-15(16)19(26-27-20)17-9-8-13(11-18(17)29)21(22,23)24/h8-9,11,14,29H,2-7,10,12H2,1H3,(H,25,27)/t14-/m1/s1 | | Definition date: | 2024-12-16 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (2P)-2-(4-{[(3R)-1-methylpiperidin-3-yl]amino}-5,6,7,8-tetrahydrophthalazin-1-yl)-5-(trifluoromethyl)phenol |
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 | | A1BLR | | Name: | (2M)-2-(6-{[(3R)-1-methylpiperidin-3-yl]amino}pyridazin-3-yl)-5-(trifluoromethyl)phenol | | Formula: | C17 H19 F3 N4 O | | SMILES: | CN1CCCC(Nc2ccc(nn2)c2ccc(cc2O)C(F)(F)F)C1 | | InChi: | InChI=1S/C17H19F3N4O/c1-24-8-2-3-12(10-24)21-16-7-6-14(22-23-16)13-5-4-11(9-15(13)25)17(18,19)20/h4-7,9,12,25H,2-3,8,10H2,1H3,(H,21,23)/t12-/m1/s1 | | Definition date: | 2024-12-16 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (2M)-2-(6-{[(3R)-1-methylpiperidin-3-yl]amino}pyridazin-3-yl)-5-(trifluoromethyl)phenol |
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 | | A1BLV | | Name: | (1R)-1-({(6M)-2-(methylamino)-6-[3-(pyrrolidin-1-yl)phenyl]pyrimidin-4-yl}amino)-2,3-dihydro-1H-indene-4-carbonitrile | | Formula: | C25 H26 N6 | | SMILES: | N#Cc1cccc2c1CCC2Nc1cc(nc(NC)n1)c1cccc(c1)N1CCCC1 | | InChi: | InChI=1S/C25H26N6/c1-27-25-29-23(17-6-4-8-19(14-17)31-12-2-3-13-31)15-24(30-25)28-22-11-10-20-18(16-26)7-5-9-21(20)22/h4-9,14-15,22H,2-3,10-13H2,1H3,(H2,27,28,29,30)/t22-/m1/s1 | | Definition date: | 2024-12-17 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (1R)-1-({(6M)-2-(methylamino)-6-[3-(pyrrolidin-1-yl)phenyl]pyrimidin-4-yl}amino)-2,3-dihydro-1H-indene-4-carbonitrile |
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 | | A1BN6 | | Name: | (3S)-1-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)acetyl]piperidine-3-carboxamide | | Formula: | C15 H21 N3 O3 | | SMILES: | O=C(CC1=C(C)C=C(C)NC1=O)N1CCCC(C1)C(N)=O | | InChi: | InChI=1S/C15H21N3O3/c1-9-6-10(2)17-15(21)12(9)7-13(19)18-5-3-4-11(8-18)14(16)20/h6,11H,3-5,7-8H2,1-2H3,(H2,16,20)(H,17,21)/t11-/m0/s1 | | Definition date: | 2025-01-10 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (3S)-1-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)acetyl]piperidine-3-carboxamide |
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 | | A1BN7 | | Name: | (3S)-1-[(5-chloro-1,2-thiazol-4-yl)di(fluoro)acetyl]piperidine-3-carboxamide | | Formula: | C11 H12 Cl F2 N3 O2 S | | SMILES: | FC(F)(c1cnsc1Cl)C(=O)N1CCCC(C1)C(N)=O | | InChi: | InChI=1S/C11H12ClF2N3O2S/c12-8-7(4-16-20-8)11(13,14)10(19)17-3-1-2-6(5-17)9(15)18/h4,6H,1-3,5H2,(H2,15,18)/t6-/m0/s1 | | Definition date: | 2025-01-10 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (3S)-1-[(5-chloro-1,2-thiazol-4-yl)di(fluoro)acetyl]piperidine-3-carboxamide |
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 | | A1BNZ | | Name: | (3S)-1-[(2S)-3-(4-fluorophenyl)-2-phenylpropanoyl]piperidine-3-carboxamide | | Formula: | C21 H23 F N2 O2 | | SMILES: | O=C(C(Cc1ccc(F)cc1)c1ccccc1)N1CCCC(C1)C(N)=O | | InChi: | InChI=1S/C21H23FN2O2/c22-18-10-8-15(9-11-18)13-19(16-5-2-1-3-6-16)21(26)24-12-4-7-17(14-24)20(23)25/h1-3,5-6,8-11,17,19H,4,7,12-14H2,(H2,23,25)/t17-,19-/m0/s1 | | Definition date: | 2025-01-10 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (3S)-1-[(2S)-3-(4-fluorophenyl)-2-phenylpropanoyl]piperidine-3-carboxamide |
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 | | A1BO8 | | Name: | (3S)-1-[(2S)-2-(methoxymethyl)oxane-2-carbonyl]piperidine-3-carboxamide | | Formula: | C14 H24 N2 O4 | | SMILES: | O=C(N1CCCC(C1)C(N)=O)C1(COC)CCCCO1 | | InChi: | InChI=1S/C14H24N2O4/c1-19-10-14(6-2-3-8-20-14)13(18)16-7-4-5-11(9-16)12(15)17/h11H,2-10H2,1H3,(H2,15,17)/t11-,14-/m0/s1 | | Definition date: | 2025-01-10 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (3S)-1-[(2S)-2-(methoxymethyl)oxane-2-carbonyl]piperidine-3-carboxamide |
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 | | A1BOB | | Name: | (3S)-1-[(3-methylpyridin-4-yl)acetyl]piperidine-3-carboxamide | | Formula: | C14 H19 N3 O2 | | SMILES: | O=C(Cc1ccncc1C)N1CCCC(C1)C(N)=O | | InChi: | InChI=1S/C14H19N3O2/c1-10-8-16-5-4-11(10)7-13(18)17-6-2-3-12(9-17)14(15)19/h4-5,8,12H,2-3,6-7,9H2,1H3,(H2,15,19)/t12-/m0/s1 | | Definition date: | 2025-01-10 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (3S)-1-[(3-methylpyridin-4-yl)acetyl]piperidine-3-carboxamide |
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 | | A1BOE | | Name: | (3S)-1-[(2-methoxyphenyl)methyl]-6-oxopiperidine-3-carboxamide | | Formula: | C14 H18 N2 O3 | | SMILES: | NC(=O)C1CCC(=O)N(Cc2ccccc2OC)C1 | | InChi: | InChI=1S/C14H18N2O3/c1-19-12-5-3-2-4-10(12)8-16-9-11(14(15)18)6-7-13(16)17/h2-5,11H,6-9H2,1H3,(H2,15,18)/t11-/m0/s1 | | Definition date: | 2025-01-10 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (3S)-1-[(2-methoxyphenyl)methyl]-6-oxopiperidine-3-carboxamide |
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 | | A1BOF | | Name: | (3S)-1-[(2S)-2-phenyl-2-(1H-pyrazol-1-yl)acetyl]piperidine-3-carboxamide | | Formula: | C17 H20 N4 O2 | | SMILES: | O=C(C(c1ccccc1)n1cccn1)N1CCCC(C1)C(N)=O | | InChi: | InChI=1S/C17H20N4O2/c18-16(22)14-8-4-10-20(12-14)17(23)15(21-11-5-9-19-21)13-6-2-1-3-7-13/h1-3,5-7,9,11,14-15H,4,8,10,12H2,(H2,18,22)/t14-,15-/m0/s1 | | Definition date: | 2025-01-10 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (3S)-1-[(2S)-2-phenyl-2-(1H-pyrazol-1-yl)acetyl]piperidine-3-carboxamide |
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 | | A1BOQ | | Name: | (3S)-1-[(3-cyano-2-methoxyphenyl)acetyl]piperidine-3-carboxamide | | Formula: | C16 H19 N3 O3 | | SMILES: | O=C(Cc1cccc(C#N)c1OC)N1CCCC(C1)C(N)=O | | InChi: | InChI=1S/C16H19N3O3/c1-22-15-11(4-2-5-12(15)9-17)8-14(20)19-7-3-6-13(10-19)16(18)21/h2,4-5,13H,3,6-8,10H2,1H3,(H2,18,21)/t13-/m0/s1 | | Definition date: | 2025-01-10 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (3S)-1-[(3-cyano-2-methoxyphenyl)acetyl]piperidine-3-carboxamide |
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 | | A1BOR | | Name: | (3S)-1-[(2H-1,3-benzodioxol-4-yl)methyl]-6-oxopiperidine-3-carboxamide | | Formula: | C14 H16 N2 O4 | | SMILES: | NC(=O)C1CCC(=O)N(C1)Cc1cccc2OCOc12 | | InChi: | InChI=1S/C14H16N2O4/c15-14(18)10-4-5-12(17)16(7-10)6-9-2-1-3-11-13(9)20-8-19-11/h1-3,10H,4-8H2,(H2,15,18)/t10-/m0/s1 | | Definition date: | 2025-01-10 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (3S)-1-[(2H-1,3-benzodioxol-4-yl)methyl]-6-oxopiperidine-3-carboxamide |
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 | | A1BOU | | Name: | (3S)-N~1~-(2-chloro-6-methoxyphenyl)piperidine-1,3-dicarboxamide | | Formula: | C14 H18 Cl N3 O3 | | SMILES: | O=C(Nc1c(OC)cccc1Cl)N1CCCC(C1)C(N)=O | | InChi: | InChI=1S/C14H18ClN3O3/c1-21-11-6-2-5-10(15)12(11)17-14(20)18-7-3-4-9(8-18)13(16)19/h2,5-6,9H,3-4,7-8H2,1H3,(H2,16,19)(H,17,20)/t9-/m0/s1 | | Definition date: | 2025-01-10 | | Last modified: | 2025-02-21 | | Release date: | 2025-02-26 | | Identifier: | (3S)-N~1~-(2-chloro-6-methoxyphenyl)piperidine-1,3-dicarboxamide |
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