 | | A1D67 | | Name: | 5-(2-azanylethyl)-4-methyl-1,3-thiazol-2-amine | | Formula: | C6 H11 N3 S | | SMILES: | Cc1nc(N)sc1CCN | | InChi: | InChI=1S/C6H11N3S/c1-4-5(2-3-7)10-6(8)9-4/h2-3,7H2,1H3,(H2,8,9) | | Synonyms: | Amthamine | | Definition date: | 2024-03-29 | | Last modified: | 2024-05-31 | | Release date: | 2024-06-05 | | Identifier: | 5-(2-azanylethyl)-4-methyl-1,3-thiazol-2-amine |
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 | | F9M | | Name: | [6-[[4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]pyridin-3-yl]-[(1~{S},5~{R})-3-[5-(trifluoromethyl)pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone | | Formula: | C25 H23 F3 N8 O S2 | | SMILES: | Cc1sc(c(C)n1)c2csc(Nc3ccc(cn3)C(=O)N4[CH]5CC[CH]4CN(C5)c6ncc(cn6)C(F)(F)F)n2 | | InChi: | InChI=1S/C25H23F3N8OS2/c1-13-21(39-14(2)32-13)19-12-38-24(33-19)34-20-6-3-15(7-29-20)22(37)36-17-4-5-18(36)11-35(10-17)23-30-8-16(9-31-23)25(26,27)28/h3,6-9,12,17-18H,4-5,10-11H2,1-2H3,(H,29,33,34)/t17-,18+ | | Definition date: | 2023-07-04 | | Last modified: | 2024-05-03 | | Release date: | 2024-05-08 | | Identifier: | [6-[[4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-yl]amino]pyridin-3-yl]-[(1~{S},5~{R})-3-[5-(trifluoromethyl)pyrimidin-2-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone |
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 | | A1H6E | | Name: | 7-[(2-chloranyl-1,3-benzothiazol-6-yl)sulfonyl]-~{N}-[(3-chloranyl-4-phenyl-phenyl)methyl]-7-azaspiro[3.5]nonan-2-amine | | Formula: | C28 H27 Cl2 N3 O2 S2 | | SMILES: | Clc1sc2cc(ccc2n1)[S](=O)(=O)N3CCC4(CC3)CC(C4)NCc5ccc(c(Cl)c5)c6ccccc6 | | InChi: | InChI=1S/C28H27Cl2N3O2S2/c29-24-14-19(6-8-23(24)20-4-2-1-3-5-20)18-31-21-16-28(17-21)10-12-33(13-11-28)37(34,35)22-7-9-25-26(15-22)36-27(30)32-25/h1-9,14-15,21,31H,10-13,16-18H2 | | Synonyms: | GW2331 | | Definition date: | 2024-03-20 | | Last modified: | 2024-04-26 | | Release date: | 2024-05-01 | | Identifier: | 7-[(2-chloranyl-1,3-benzothiazol-6-yl)sulfonyl]-~{N}-[(3-chloranyl-4-phenyl-phenyl)methyl]-7-azaspiro[3.5]nonan-2-amine |
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 | | WCK | | Name: | (4P)-4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl]pyrimidin-2-amine | | Formula: | C18 H20 N6 O S | | SMILES: | Cc1nc(N)sc1c1nc(Nc2ccc(cc2)N2CCOCC2)ncc1 | | InChi: | InChI=1S/C18H20N6OS/c1-12-16(26-17(19)21-12)15-6-7-20-18(23-15)22-13-2-4-14(5-3-13)24-8-10-25-11-9-24/h2-7H,8-11H2,1H3,(H2,19,21)(H,20,22,23) | | Definition date: | 2023-09-29 | | Last modified: | 2024-04-12 | | Release date: | 2024-04-17 | | Identifier: | (4P)-4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl]pyrimidin-2-amine |
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 | | Y4E | | Name: | [(1~{R},3~{a}~{R})-1,3,3~{a},4-tetrahydro-[1,3]thiazolo[3,4-a]benzimidazol-1-yl]methanethiol | | Formula: | C10 H12 N2 S2 | | SMILES: | SC[CH]1SC[CH]2Nc3ccccc3N12 | | InChi: | InChI=1S/C10H12N2S2/c13-5-10-12-8-4-2-1-3-7(8)11-9(12)6-14-10/h1-4,9-11,13H,5-6H2/t9-,10-/m1/s1 | | Definition date: | 2023-11-20 | | Last modified: | 2024-04-05 | | Release date: | 2024-04-10 | | Identifier: | [(1~{R},3~{a}~{R})-1,3,3~{a},4-tetrahydro-[1,3]thiazolo[3,4-a]benzimidazol-1-yl]methanethiol |
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 | | YNZ | | Name: | (2S)-N~1~-[(4P)-2-tert-butyl-4'-methyl[4,5'-bi-1,3-thiazol]-2'-yl]pyrrolidine-1,2-dicarboxamide | | Formula: | C17 H23 N5 O2 S2 | | SMILES: | CC(C)(C)c1nc(cs1)c1sc(NC(=O)N2CCCC2C(N)=O)nc1C | | InChi: | InChI=1S/C17H23N5O2S2/c1-9-12(10-8-25-14(20-10)17(2,3)4)26-15(19-9)21-16(24)22-7-5-6-11(22)13(18)23/h8,11H,5-7H2,1-4H3,(H2,18,23)(H,19,21,24)/t11-/m0/s1 | | Definition date: | 2023-12-07 | | Last modified: | 2024-03-15 | | Release date: | 2024-03-20 | | Identifier: | (2S)-N~1~-[(4P)-2-tert-butyl-4'-methyl[4,5'-bi-1,3-thiazol]-2'-yl]pyrrolidine-1,2-dicarboxamide |
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 | | ZLO | | Name: | ~{N}-(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)ethanamide | | Formula: | C5 H7 N3 O S2 | | SMILES: | CSc1nsc(NC(C)=O)n1 | | InChi: | InChI=1S/C5H7N3OS2/c1-3(9)6-4-7-5(10-2)8-11-4/h1-2H3,(H,6,7,8,9) | | Definition date: | 2023-06-28 | | Last modified: | 2024-01-26 | | Release date: | 2024-01-31 | | Identifier: | ~{N}-(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)ethanamide |
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 | | YA6 | | Name: | N-{(4P)-4-[(4P)-5-{3-[(8-fluoro-11-oxo-5,11-dihydro-10H-dibenzo[b,e][1,4]diazepin-10-yl)methyl]phenyl}-2-(methylsulfanyl)-1H-imidazol-4-yl]pyridin-2-yl}acetamide | | Formula: | C31 H25 F N6 O2 S | | SMILES: | CC(=O)Nc1nccc(c1)c1nc(SC)[NH]c1c1cccc(c1)CN1c2cc(F)ccc2Nc2ccccc2C1=O | | InChi: | InChI=1S/C31H25FN6O2S/c1-18(39)34-27-15-21(12-13-33-27)29-28(36-31(37-29)41-2)20-7-5-6-19(14-20)17-38-26-16-22(32)10-11-25(26)35-24-9-4-3-8-23(24)30(38)40/h3-16,35H,17H2,1-2H3,(H,36,37)(H,33,34,39) | | Definition date: | 2023-01-19 | | Last modified: | 2024-01-12 | | Release date: | 2024-01-17 | | Identifier: | N-{(4P)-4-[(4P)-5-{3-[(8-fluoro-11-oxo-5,11-dihydro-10H-dibenzo[b,e][1,4]diazepin-10-yl)methyl]phenyl}-2-(methylsulfanyl)-1H-imidazol-4-yl]pyridin-2-yl}acetamide |
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 | | YAA | | Name: | N-{(3P)-3-[(4P)-4-(2-acetamidopyridin-4-yl)-2-(methylsulfanyl)-1H-imidazol-5-yl]phenyl}-11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepine-9-carboxamide | | Formula: | C31 H25 N7 O3 S | | SMILES: | CC(=O)Nc1nccc(c1)c1nc(SC)[NH]c1c1cc(ccc1)NC(=O)c1cccc2Nc3ccccc3C(=O)Nc12 | | InChi: | InChI=1S/C31H25N7O3S/c1-17(39)33-25-16-19(13-14-32-25)27-26(37-31(38-27)42-2)18-7-5-8-20(15-18)34-30(41)22-10-6-12-24-28(22)36-29(40)21-9-3-4-11-23(21)35-24/h3-16,35H,1-2H3,(H,34,41)(H,36,40)(H,37,38)(H,32,33,39) | | Definition date: | 2023-01-19 | | Last modified: | 2024-01-12 | | Release date: | 2024-01-17 | | Identifier: | N-{(3P)-3-[(4P)-4-(2-acetamidopyridin-4-yl)-2-(methylsulfanyl)-1H-imidazol-5-yl]phenyl}-11-oxo-10,11-dihydro-5H-dibenzo[b,e][1,4]diazepine-9-carboxamide |
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 | | T8O | | Name: | 4-[(difluoromethyl)sulfanyl]aniline | | Formula: | C7 H7 F2 N S | | SMILES: | FC(F)Sc1ccc(N)cc1 | | InChi: | InChI=1S/C7H7F2NS/c8-7(9)11-6-3-1-5(10)2-4-6/h1-4,7H,10H2 | | Definition date: | 2023-08-28 | | Last modified: | 2023-11-24 | | Release date: | 2023-11-29 | | Identifier: | 4-[(difluoromethyl)sulfanyl]aniline |
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 | | LFL | | Name: | (2S,3R,4R,5S,6R)-2-[4-chloranyl-3-[(4-ethoxyphenyl)methyl]phenyl]-6-methylsulfanyl-oxane-3,4,5-triol | | Formula: | C21 H25 Cl O5 S | | SMILES: | CCOc1ccc(Cc2cc(ccc2Cl)[CH]3O[CH](SC)[CH](O)[CH](O)[CH]3O)cc1 | | InChi: | InChI=1S/C21H25ClO5S/c1-3-26-15-7-4-12(5-8-15)10-14-11-13(6-9-16(14)22)20-18(24)17(23)19(25)21(27-20)28-2/h4-9,11,17-21,23-25H,3,10H2,1-2H3/t17-,18-,19+,20+,21-/m1/s1 | | Synonyms: | Sotagliflozin | | Definition date: | 2022-11-18 | | Last modified: | 2023-11-10 | | Release date: | 2023-11-15 | | Identifier: | (2~{S},3~{R},4~{R},5~{S},6~{R})-2-[4-chloranyl-3-[(4-ethoxyphenyl)methyl]phenyl]-6-methylsulfanyl-oxane-3,4,5-triol |
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 | | MW6 | | Name: | (3S)-3-[(3-aminophenyl)sulfanylmethyl]piperidine-2,6-dione | | Formula: | C12 H14 N2 O2 S | | SMILES: | Nc1cccc(SC[CH]2CCC(=O)NC2=O)c1 | | InChi: | InChI=1S/C12H14N2O2S/c13-9-2-1-3-10(6-9)17-7-8-4-5-11(15)14-12(8)16/h1-3,6,8H,4-5,7,13H2,(H,14,15,16)/t8-/m1/s1 | | Definition date: | 2022-08-04 | | Last modified: | 2023-09-23 | | Release date: | 2023-01-11 | | Identifier: | (3~{S})-3-[(3-aminophenyl)sulfanylmethyl]piperidine-2,6-dione |
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 | | 1ME | | Name: | (2S)-2-AMINO-3-METHYLSULFANYL-BUTANOIC ACID | | Formula: | C5 H11 N O2 S | | SMILES: | CS[CH](C)[CH](N)C(O)=O | | InChi: | InChI=1S/C5H11NO2S/c1-3(9-2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t3-,4+/m0/s1 | | Definition date: | 2011-01-24 | | Last modified: | 2023-09-23 | | Identifier: | (2~{S})-2-azanyl-3-methylsulfanyl-butanoic acid |
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 | | V3O | | Name: | N-[(4P)-2-(4-chloroanilino)-4'-methyl[4,5'-bi-1,3-thiazol]-2'-yl]acetamide | | Formula: | C15 H13 Cl N4 O S2 | | SMILES: | CC(=O)Nc1nc(C)c(s1)c1csc(Nc2ccc(Cl)cc2)n1 | | InChi: | InChI=1S/C15H13ClN4OS2/c1-8-13(23-15(17-8)18-9(2)21)12-7-22-14(20-12)19-11-5-3-10(16)4-6-11/h3-7H,1-2H3,(H,19,20)(H,17,18,21) | | Definition date: | 2023-09-07 | | Last modified: | 2023-09-22 | | Release date: | 2023-09-27 | | Identifier: | N-[(4P)-2-(4-chloroanilino)-4'-methyl[4,5'-bi-1,3-thiazol]-2'-yl]acetamide |
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 | | ZI9 | | Name: | 3-[(6-ethynyl-[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-bis(fluoranyl)benzamide | | Formula: | C16 H9 F2 N3 O2 S | | SMILES: | NC(=O)c1c(F)ccc(OCc2sc3ncc(cc3n2)C#C)c1F | | InChi: | InChI=1S/C16H9F2N3O2S/c1-2-8-5-10-16(20-6-8)24-12(21-10)7-23-11-4-3-9(17)13(14(11)18)15(19)22/h1,3-6H,7H2,(H2,19,22) | | Definition date: | 2023-01-05 | | Last modified: | 2023-09-15 | | Release date: | 2023-09-20 | | Identifier: | 3-[(6-ethynyl-[1,3]thiazolo[5,4-b]pyridin-2-yl)methoxy]-2,6-bis(fluoranyl)benzamide |
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 | | IC2 | | Name: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione | | Formula: | C20 H17 F3 N4 O2 S | | SMILES: | CC1(C)N(Cc2c[nH]c3ncccc23)C(=O)N(C1=O)c4ccc(SC(F)(F)F)cc4 | | InChi: | InChI=1S/C20H17F3N4O2S/c1-19(2)17(28)27(13-5-7-14(8-6-13)30-20(21,22)23)18(29)26(19)11-12-10-25-16-15(12)4-3-9-24-16/h3-10H,11H2,1-2H3,(H,24,25) | | Definition date: | 2023-07-28 | | Last modified: | 2023-09-15 | | Release date: | 2023-09-20 | | Identifier: | 5,5-dimethyl-1-(1~{H}-pyrrolo[2,3-b]pyridin-3-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione |
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 | | IE0 | | Name: | (5S)-5-methyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione | | Formula: | C19 H15 F3 N4 O2 S | | SMILES: | C[CH]1N(Cc2ccnc3[nH]ccc23)C(=O)N(C1=O)c4ccc(SC(F)(F)F)cc4 | | InChi: | InChI=1S/C19H15F3N4O2S/c1-11-17(27)26(13-2-4-14(5-3-13)29-19(20,21)22)18(28)25(11)10-12-6-8-23-16-15(12)7-9-24-16/h2-9,11H,10H2,1H3,(H,23,24)/t11-/m0/s1 | | Definition date: | 2023-07-28 | | Last modified: | 2023-09-15 | | Release date: | 2023-09-20 | | Identifier: | (5~{S})-5-methyl-1-(1~{H}-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione |
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 | | IED | | Name: | 5,5-dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione | | Formula: | C20 H17 F3 N4 O2 S | | SMILES: | CC1(C)N(Cc2ccnc3[nH]ccc23)C(=O)N(C1=O)c4ccc(SC(F)(F)F)cc4 | | InChi: | InChI=1S/C20H17F3N4O2S/c1-19(2)17(28)27(13-3-5-14(6-4-13)30-20(21,22)23)18(29)26(19)11-12-7-9-24-16-15(12)8-10-25-16/h3-10H,11H2,1-2H3,(H,24,25) | | Definition date: | 2023-07-28 | | Last modified: | 2023-09-15 | | Release date: | 2023-09-20 | | Identifier: | 5,5-dimethyl-1-(1~{H}-pyrrolo[2,3-b]pyridin-4-ylmethyl)-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidine-2,4-dione |
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 | | WFI | | Name: | 1-[4-methyl-2-(pyridin-4-yl)-1,3-thiazol-5-yl]methanamine | | Formula: | C10 H11 N3 S | | SMILES: | NCc1sc(nc1C)c1ccncc1 | | InChi: | InChI=1S/C10H11N3S/c1-7-9(6-11)14-10(13-7)8-2-4-12-5-3-8/h2-5H,6,11H2,1H3 | | Definition date: | 2022-09-06 | | Last modified: | 2023-09-08 | | Release date: | 2023-09-13 | | Identifier: | 1-[4-methyl-2-(pyridin-4-yl)-1,3-thiazol-5-yl]methanamine |
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 | | P6I | | Name: | N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-[4-(methylsulfanyl)phenyl]acetamide | | Formula: | C23 H19 Cl N2 O S2 | | SMILES: | Clc1cc(CN(C(=O)Cc2cncc3ccccc32)c2ccc(SC)cc2)sc1 | | InChi: | InChI=1S/C23H19ClN2OS2/c1-28-20-8-6-19(7-9-20)26(14-21-11-18(24)15-29-21)23(27)10-17-13-25-12-16-4-2-3-5-22(16)17/h2-9,11-13,15H,10,14H2,1H3 | | Definition date: | 2022-05-25 | | Last modified: | 2023-08-25 | | Release date: | 2023-08-30 | | Identifier: | N-[(4-chlorothiophen-2-yl)methyl]-2-(isoquinolin-4-yl)-N-[4-(methylsulfanyl)phenyl]acetamide |
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 | | MUO | | Name: | 2-[2,6-dimethyl-4-[(~{E})-3-(4-methylsulfanylphenyl)-3-oxidanylidene-prop-1-enyl]phenoxy]-2-methyl-propanoic acid | | Formula: | C22 H24 O4 S | | SMILES: | CSc1ccc(cc1)C(=O)C=Cc2cc(C)c(OC(C)(C)C(O)=O)c(C)c2 | | InChi: | InChI=1S/C22H24O4S/c1-14-12-16(13-15(2)20(14)26-22(3,4)21(24)25)6-11-19(23)17-7-9-18(27-5)10-8-17/h6-13H,1-5H3,(H,24,25)/b11-6+ | | Synonyms: | elafibranor | | Definition date: | 2023-01-05 | | Last modified: | 2023-08-04 | | Release date: | 2023-08-09 | | Identifier: | 2-[2,6-dimethyl-4-[(~{E})-3-(4-methylsulfanylphenyl)-3-oxidanylidene-prop-1-enyl]phenoxy]-2-methyl-propanoic acid |
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 | | IYV | | Name: | (2R,3R,4S,5R,6R)-2-[(1R,2R)-1-azanyl-2-oxidanyl-propyl]-6-methylsulfanyl-oxane-3,4,5-triol | | Formula: | C9 H19 N O5 S | | SMILES: | CS[CH]1O[CH]([CH](N)[CH](C)O)[CH](O)[CH](O)[CH]1O | | InChi: | InChI=1S/C9H19NO5S/c1-3(11)4(10)8-6(13)5(12)7(14)9(15-8)16-2/h3-9,11-14H,10H2,1-2H3/t3-,4-,5+,6-,7-,8-,9-/m1/s1 | | Definition date: | 2022-08-04 | | Last modified: | 2023-07-28 | | Release date: | 2023-08-02 | | Identifier: | (2~{R},3~{R},4~{S},5~{R},6~{R})-2-[(1~{R},2~{R})-1-azanyl-2-oxidanyl-propyl]-6-methylsulfanyl-oxane-3,4,5-triol |
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 | | ZV2 | | Name: | 2-(2-azanyl-1,3-thiazol-3-yl)-~{N}-(4-fluorophenyl)ethanamide | | Formula: | C11 H11 F N3 O S | | SMILES: | Nc1scc[n]1CC(=O)Nc2ccc(F)cc2 | | InChi: | InChI=1S/C11H11FN3OS/c12-8-1-3-9(4-2-8)14-10(16)7-15-5-6-17-11(15)13/h1-6H,7,13H2,(H,14,16) | | Definition date: | 2023-07-05 | | Last modified: | 2023-07-21 | | Release date: | 2023-07-26 | | Identifier: | 2-(2-azanyl-1,3-thiazol-3-yl)-~{N}-(4-fluorophenyl)ethanamide |
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 | | WJQ | | Name: | (5s,8s)-8-(3-bromophenyl)-7,9-dioxa-1-thia-3-azaspiro[4.5]decane-2,4-dione | | Formula: | C12 H10 Br N O4 S | | SMILES: | Brc1cccc(c1)C1OCC2(CO1)SC(=O)NC2=O | | InChi: | InChI=1S/C12H10BrNO4S/c13-8-3-1-2-7(4-8)9-17-5-12(6-18-9)10(15)14-11(16)19-12/h1-4,9H,5-6H2,(H,14,15,16)/t9-,12+ | | Definition date: | 2023-05-15 | | Last modified: | 2023-06-09 | | Release date: | 2023-06-14 | | Identifier: | (5s,8s)-8-(3-bromophenyl)-7,9-dioxa-1-thia-3-azaspiro[4.5]decane-2,4-dione |
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 | | WKW | | Name: | 2-{[(3M)-3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-4,5-dimethylthiophen-2-yl]carbamoyl}cyclohex-1-ene-1-carboxylic acid | | Formula: | C19 H21 N3 O4 S | | SMILES: | O=C(Nc1sc(C)c(C)c1c1nc(no1)C1CC1)C=1CCCCC=1C(=O)O | | InChi: | InChI=1S/C19H21N3O4S/c1-9-10(2)27-18(14(9)17-20-15(22-26-17)11-7-8-11)21-16(23)12-5-3-4-6-13(12)19(24)25/h11H,3-8H2,1-2H3,(H,21,23)(H,24,25) | | Definition date: | 2023-05-15 | | Last modified: | 2023-06-09 | | Release date: | 2023-06-14 | | Identifier: | 2-{[(3M)-3-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)-4,5-dimethylthiophen-2-yl]carbamoyl}cyclohex-1-ene-1-carboxylic acid |
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