 | | PRD_000159 | | Name: | Zervamicin IIB | | Formula: | C90 H139 N19 O22 | | Description: | ZERVAMICIN IS A HEXADECAMERIC HELICAL PEPTIDE.
THE N-TERM IS ACETYLATED (RESIDUE 0) | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000160 | | Name: | TRICHOTOXIN A50E | | Formula: | C78 H136 N20 O21 | | Description: | TRICHOTOXIN_A50E IS AN OCTADECAMERIC HELICAL PEPTIDE.
THE N-TERM IS ACETYLATED (RESIDUE 0) | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000161 | | Name: | Antiamoebin 1 | | Formula: | C82 H127 N17 O20 | | Description: | ANTIAMOEBIN I IS A HEXADECAMERIC HELICAL PEPTIDE.
THE N-TERM IS ACETYLATED (RESIDUE 0) | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000162 | | Name: | Chrysospermin-C | | Formula: | C91 H142 N22 O23 | | Description: | CHRYSOSPERMIN C IS A NONADECAMERIC HELICAL PEPTIDE.
THE N-TERM IS ACETYLATED (RESIDUE 0) | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000163 | | Name: | Alamethicin | | Formula: | C92 H150 N22 O25 | | Description: | ALAMETHICIN F30 IS AN EICOSAMERIC HELICAL PEPTIDE.
THE N-TERM IS ACETYLATED (RESIDUE 0) | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000185 | | Name: | SURFACTIN nC15 | | Formula: | C52 H91 N7 O13 | | Definition date: | 2020-08-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000186 | | Name: | EFRAPEPTIN C | | Formula: | C80 H138 N18 O16 | | Description: | EFRAPEPTIN C IS A LINEAR PEPTIDE, WITH ACETYLATED
(ACE) PIPECOLIC ACID (YCP) AT THE N-TERMINUS AND
A MODIFIED LEUCINE AT THE C-TERM (TLX) | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000187 | | Name: | SCYPTOLIN A | | Formula: | C45 H71 Cl N8 O14 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000193 | | Name: | Capreomycin IA | | Formula: | C25 H44 N14 O8 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000194 | | Name: | ACTAGARDINE | | Formula: | C81 H124 N20 O23 S4 | | Description: | ACTAGARDINE IS A TRICYCLIC PEPTIDE. POST TRANSLATIONAL MATURATION
OF LANTIBIOTICS INVOLVES THE ENZYMIC CONVERSION OF THR AND SER INTO
DEHYDRATED AMINO ACIDS AND THE FORMATION OF THIOETHER BONDS WITH
CYSTEINE. THE THIOETHER BONDS WITH CYSTEINE RESULT IN THREE
RING STRUCTURES. THIS IS FOLLOWED BY MEMBRANE TRANSLOCATION AND
CLEAVAGE OF THE MODIFIED PRECURSOR. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000195 | | Name: | Cinnamycin | | Formula: | C89 H127 N25 O25 S3 | | Description: | CINNAMYCIN IS A TETRACYCLIC PEPTIDE. POST TRANSLATIONAL MATURATION
OF LANTIBIOTICS INVOLVES THE ENZYMIC CONVERSION OF THR AND SER INTO
DEHYDRATED AMINO ACIDS AND THE FORMATION OF THIOETHER BONDS WITH
CYSTEINE. THE 14-19 BETA-METHYLLANTHIONINE THIOETHER BOND IS OXIDIZED
TO A SULFOXIDE. THE THIOETHER BONDS WITH CYSTEINE RESULT IN THREE
RING STRUCTURES, CROSSLINK BETWEEN SER AND LYS RESULT IN THE FOURTH
RING. THIS IS FOLLOWED BY MEMBRANE TRANSLOCATION AND CLEAVAGE OF THE
MODIFIED PRECURSOR. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000196 | | Name: | EPILANCIN 15X | | Formula: | C145 H241 N41 O33 S3 | | Description: | Epilancin 15X is a tricyclic peptide. thioether bonds with cysteine
result in three rings along the peptide chain. Post Translational
maturation of lantibiotics involves the enzymic conversion of Thr and
Ser into dehydrated amino acids and the formation of thioether bonds
with cysteine. This is followed by membrane translocation and
cleavage of the modified precursor. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000199 | | Name: | Mersacidin | | Formula: | C80 H120 N20 O21 S4 | | Description: | MERSACIDIN IS A TETRACYCLIC PEPTIDE. POST TRANSLATIONAL MATURATION
OF LANTIBIOTICS INVOLVES THE ENZYMIC CONVERSION OF THR, AND SER INTO
DEHYDRATED AA AND THE FORMATION OF THIOETHER BONDS WITH CYSTEINE. THE
CARBOXY-TERMINAL BETA-METHYLLANTHIONINE UNDERGOES
DECARBOXYLATION. THIOETHER BONDS WITH CYSTEINE RESULT IN FOUR
RINGS. THIS IS FOLLOWED BY MEMBRANE TRANSLOCATION AND CLEAVAGE OF THE
MODIFIED PRECURSOR. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000200 | | Name: | Nisin A | | Formula: | C141 H233 N41 O38 S7 | | Description: | Nisin Z is a heptacyclic peptide. Post Translational maturation of
lantibiotics involves the enzymic conversion of Thr, and Ser into
dehydrated AA and the formation of thioether bonds with cysteine.
Thioether bonds with cysteine result in five cyclic structures along
the peptide chain. This is followed by membrane translocation and
cleavage of the modified precursor. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000201 | | Name: | Alpha-Amanitin | | Formula: | C39 H54 N10 O14 S | | Description: | ALPHA-AMANITIN, IS AN 8 AMINO-ACID PEPTIDE.
THE OUTER LOOP IS FORMED BY A PEPTIDE BOND
BETWEEN THE C- AND THE N-TERMINI. THE SIDE-CHAINS
OF RESIDUES 2 AND 8 ARE LINKED TO FORM THE INNER
LOOP. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000203 | | Name: | Chloroorienticin A | | Formula: | C73 H88 Cl2 N10 O26 | | Description: | CHLOROORIENTICIN A IS A TRICYCLIC GLYCOPEPTIDE, GLYCOSYLATED BY ONE DISACCHARIDE ON RESIDUE 4 AND ONE MONOSACCHARIDE
ON RESIDUE 6. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000205 | | Name: | DESVANCOSAMINYL VANCOMYCIN | | Formula: | C59 H62 Cl2 N8 O22 | | Description: | DESVANCOSAMINYL VANCOMYCIN IS AN INTERMIDIATE IN VANCOMYCIN BIOSYNTHESIS. IT IS TRICYCLIC GLYCOPEPTIDE, GLYCOSYLATED
BY D-GLUCOSE (RESIDUE 8) ON RESIDUE 4. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000206 | | Name: | VANCOMYCIN AGLYCON | | Formula: | C53 H52 Cl2 N8 O17 | | Description: | VANCOMYCIN AGLYCON IS THE NONSUGAR COMPONENT OF VANCOMYCIN, CONSISTING OF THE TRICYCLIC HEPTAPEPTIDE ONLY. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000207 | | Name: | Decaplanin | | Formula: | C72 H86 Cl N9 O28 | | Description: | DECAPLANIN IS A TRICYCLIC GLYCOPEPTIDE. THE SCAFFOLD IS A HEPTAPEPTIDE WITH THE CONFIGURATION D-D-L-D-D-L-L,
GLYCOSYLATED | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000209 | | Name: | Teicoplanin A2-2 beta-D-Glucopyranuronic acid | | Formula: | C88 H97 Cl2 N9 O33 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000210 | | Name: | Teicoplanin Aglycone | | Formula: | C58 H45 Cl2 N7 O18 | | Description: | TEICOPLANIN AGLYCON IS THE NONSUGAR COMPONENT OF
TEICOPLANIN, CONSISTING OF THE TETRACYCLIC
HEPTAPEPTIDE ONLY. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000211 | | Name: | A40926 | | Formula: | C88 H95 Cl2 N9 O34 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000216 | | Name: | LEUPEPTIN | | Formula: | C20 H41 N6 O5 | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000217 | | Name: | Daptomycin | | Formula: | C72 H101 N17 O26 | | Description: |
DAPTOMYCIN IS AN ACIDIC CYCLIC LIPOPEPTIDE.
THE SCAFFOLD IS MADE OF TWO PARTS:
(1) THREE RESIDUES N-TERM EXOCYCLIC PART
(2) A DECAPEPTIDE LACTONE RING DERIVED FROM
CYCLISATION OF THR3 SIDE CHAIN ONTO THE C-TER
CARBOXYL GROUP
THE N-DECANOYL FATTY ACID IS LINKED TO THE
MAIN BODY OF THE MOLECULE VIA N-TERM ACYLATION. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
|
 | | PRD_000219 | | Name: | GRAMICIDIN S | | Formula: | C60 H92 N12 O10 | | Description: | GRAMICIDIN S IS A DECAPEPTIDE,
RESIDUES 1 AND 10 FORM A PEPTIDE BOND
RESULTING IN CYCLIZATION. | | Definition date: | 2012-12-12 | | Last modified: | 2023-09-20 |
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