9VD2

Crystal Structure of kelch domain of human KEAP1 in complex with CH7286675

This is a non-PDB format compatible entry.

Summary for 9VD2

• Entry DOI: 10.2210/pdb9vd2/pdb
• Descriptor: Kelch-like ECH-associated protein 1, 4-[3-[2,6-dichloro-4-(6-methoxy-2-azaspiro[3.3]heptan-2-yl)benzoyl]-2,4-dihydro-1,3-benzoxazin-8-yl]-5-fluoro-2-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)benzoic acid, ACETATE ION, ... (5 entities in total)
• Functional Keywords: beta-propeller, kelch repeat motif, protein bindin, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 33419.22

Authors

Kawauchi, H.,Fukami, T.A.,Kimbara, A.,Miyagi, T.,Yasui, Y.,Hoshino, M.,Irie, M.,Torizawa, T. (deposition date: 2025-06-07, release date: 2025-10-15)

• Primary citation: Kawauchi, H.; Crystal Structure of kelch domain of human KEAP1 in complex with CH7286675; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.699 Å)