9V7G

Phycobilisome Rx rod from Gloeobacter violaceus PCC 7421

9V7G の概要

• エントリーDOI: 10.2210/pdb9v7g/pdb
• EMDBエントリー: 64812
• 分子名称: Glr2806 protein, Phycocyanin alpha chain, Phycocyanin beta chain, ... (4 entities in total)
• 機能のキーワード: phycobilisome, photosynthesis
• 由来する生物種: Gloeobacter violaceus PCC 7421; 詳細
• タンパク質・核酸の鎖数: 13
• 化学式量合計: 309093.63

構造登録者

Burtseva, A.D.,Baymukhametov, T.N.,Slonimskiy, Y.B.,Popov, V.O.,Sluchanko, N.N.,Boyko, K.M. (登録日: 2025-05-28, 公開日: 2025-09-24, 最終更新日: 2025-10-29)

主引用文献

Burtseva, A.D.,Slonimskiy, Y.B.,Baymukhametov, T.N.,Sinetova, M.A.,Gvozdev, D.A.,Tsoraev, G.V.,Cherepanov, D.A.,Maksimov, E.G.,Popov, V.O.,Boyko, K.M.,Sluchanko, N.N.
Structure and quenching of a bundle-shaped phycobilisome.
Sci Adv, 11:eadz6774-eadz6774, 2025

PubMed Abstract: Cyanobacteria use soluble antenna megacomplexes, phycobilisomes (PBSs), to maximize light-harvesting efficiency and small photoswitchable orange carotenoid proteins (OCPs) to down-regulate PBSs in high light. Among known PBS morphologies, the one from the basal cyanobacterial genus still lacks detailed structural characterization. Here, we reconstructed a cryo-electron microscopy structure of the >10-megadalton PBS, with diverging, conformationally mobile bundles of rods composed of stacked phycoerythrin and phycocyanin hexamers, stemming from a pentacylindrical allophycocyanin core belted by auxiliary phycocyanin hexamers. We show how two -specific multidomain linker proteins, Glr1262 and Glr2806, maintain this bundle-shaped architecture and reveal its differential regulation via nonphotochemical quenching by two OCP types of that recognize separate binding sites within the allophycocyanin core, including lateral cylinders absent in tricylindrical cores.

PubMed: 41091862
DOI: 10.1126/sciadv.adz6774

実験手法

ELECTRON MICROSCOPY (2.72 Å)