9UPZ

KCMF1 Zn-coordinating domains with RTGG peptide

Summary for 9UPZ

• Entry DOI: 10.2210/pdb9upz/pdb
• Related: 9JNI
• Descriptor: E3 ubiquitin-protein ligase KCMF1, ARG-THR-GLY-GLY, ZINC ION, ... (4 entities in total)
• Functional Keywords: complex, zz-domain, c2h2 zn-finger domain, kcmf1, arg/n-degron pathway, peptide binding protein, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 14164.16

Authors

Lee, J.Y.,Shin, J.S.,Song, H.K. (deposition date: 2025-04-29, release date: 2025-08-27)

• Primary citation: Grabarczyk, D.,Ehrmann, J.,Murphy, P.,Yang, W.,Kurzbauer, R.,Bell, L.,Deszcz, L.,Neuhold, J.,Schleiffer, A.,Shulkina, A.,Lee, J.,Shin, J.,Meinhart, A.,Versteeg, G.,Zavodszky, E.,Song, H.,Hegde, R.,Clausen, T.; Architecture of the UBR4 complex, a giant E4 ligase central to eukaryotic protein quality control; Science, 2025; DOI: 10.1126/science.adv9309

Experimental method

X-RAY DIFFRACTION (1.71 Å)