9UKP

CryoEM structure of the T.thermophilus transcription initiation complex bound to Ap4A-C, -1 dC in the template DNA strand

Summary for 9UKP

• Entry DOI: 10.2210/pdb9ukp/pdb
• EMDB information: 64252
• Descriptor: RNA polymerase sigma factor SigA, CYTIDINE-5'-MONOPHOSPHATE, BIS(ADENOSINE)-5'-TETRAPHOSPHATE, ... (13 entities in total)
• Functional Keywords: complex, transcription
• Biological source: Thermus thermophilus HB8; More
• Total number of polymer chains: 8
• Total formula weight: 460694.77

Authors

Duan, W.,Kaushik, A.,Serganov, A. (deposition date: 2025-04-18, release date: 2025-10-22)

• Primary citation: Duan, W.,Kaushik, A.,Unarta, I.C.,Wu, Y.,Liu, M.M.J.,Weaver, J.W.,Wang, B.,Rice, W.J.,Luciano, D.J.,Belasco, J.G.,Huang, X.,Nudler, E.,Serganov, A.; Molecular basis for noncanonical transcription initiation from Np4A alarmones; Nat.Chem.Biol., 2025; DOI: 10.1038/s41589-025-02044-6

Experimental method

ELECTRON MICROSCOPY (2.73 Å)