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9S71

Crystal structure of RXR alpha LBD bound to a partial agonist 35 and a coactivator fragment SRC1

This is a non-PDB format compatible entry.
Summary for 9S71
Entry DOI10.2210/pdb9s71/pdb
Related9S70
DescriptorRetinoic acid receptor RXR-alpha, Nuclear receptor coactivator 1, 3-[[4-(4,4-dimethyl-2,3-dihydroquinolin-1-yl)-6-(trifluoromethyl)pyrimidin-2-yl]amino]propanoic acid, ... (4 entities in total)
Functional Keywordspartial agonist, nuclear receptor, rxra, drug, transcription factor, ligand binding domain, transcription
Biological sourceHomo sapiens (human)
More
Total number of polymer chains2
Total formula weight29179.70
Authors
Morozov, V.,Merk, D.,Lewandowski, M. (deposition date: 2025-08-01, release date: 2025-10-29)
Primary citationMorozov, V.,Merk, D.,Lewandowski, M.
Crystal structure of RXR alpha LBD bound to a partial agonist 35 and a coactivator fragment SRC1
To Be Published,
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

245011

数据于2025-11-19公开中

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