9QB3

Dimer structure of H/ACA RNP lobe of human telomerase

This is a non-PDB format compatible entry.

Summary for 9QB3

• Entry DOI: 10.2210/pdb9qb3/pdb
• EMDB information: 52984
• Descriptor: H/ACA ribonucleoprotein complex subunit DKC1, H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, ... (6 entities in total)
• Functional Keywords: telomerase, h/aca, rna-binding protein, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 20
• Total formula weight: 830122.67

Authors

Balch, S.,Sekne, Z.,Franco-Echevarria, E.,Ludzia, P.,Kretsch, R.C.,Sun, W.,Yu, H.,Ghanim, G.E.,Sigurdur, T.R.,Ding, Y.,Das, R.,Nguyen, T.H.D. (deposition date: 2025-02-28, release date: 2025-07-16)

• Primary citation: Balch, S.,Sekne, Z.,Franco-Echevarria, E.,Ludzia, P.,Kretsch, R.C.,Sun, W.,Yu, H.,Ghanim, G.E.,Sigurdur, T.R.,Ding, Y.,Das, R.,Nguyen, T.H.D.; CryoEM structure of human telomerase dimer reveals H/ACA RNP-mediated dimerization; Science, 2025; DOI: 10.1126/science.adr5817

Experimental method

ELECTRON MICROSCOPY (3.9 Å)